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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vsp</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы современной педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Current Pediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-5527</issn><issn pub-type="epub">1682-5535</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">vsp-1364</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>РИТУКСИМАБ: НОВЫЕ ВОЗМОЖНОСТИ ЛЕЧЕНИЯ ТЯЖЕЛОГО РЕФРАКТЕРНОГО ЮВЕНИЛЬНОГО АРТРИТА</article-title><trans-title-group xml:lang="en"><trans-title>RITUXIMAB: NEW RESOURCES OF MANAGEMENT OF SEVERE REFRACTORY JUVENILE RHEUMATOID ARTHRITIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеева</surname><given-names>Е.И.</given-names></name><name name-style="western" xml:lang="en"><surname>Alexeeva</surname><given-names>E.I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бзарова</surname><given-names>Т.М.</given-names></name><name name-style="western" xml:lang="en"><surname>Bzarova</surname><given-names>T.М.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Валиева</surname><given-names>С.И.</given-names></name><name name-style="western" xml:lang="en"><surname>Valieva</surname><given-names>S.I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Исаева</surname><given-names>К.Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Isaeva</surname><given-names>K.B.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чомахидзе</surname><given-names>А.М.</given-names></name><name name-style="western" xml:lang="en"><surname>Chomakhidze</surname><given-names>A.M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семикина</surname><given-names>Е.Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Semikina</surname><given-names>E.L.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научный центр здоровья детей РАМН, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>22</day><month>10</month><year>2015</year></pub-date><volume>7</volume><issue>2</issue><issue-title>Вопросы современной педиатрии</issue-title><fpage>22</fpage><lpage>29</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Алексеева Е., Бзарова Т., Валиева С., Исаева К., Чомахидзе А., Семикина Е., 2008</copyright-statement><copyright-year>2008</copyright-year><copyright-holder xml:lang="ru">Алексеева Е., Бзарова Т., Валиева С., Исаева К., Чомахидзе А., Семикина Е.</copyright-holder><copyright-holder xml:lang="en">Alexeeva E., Bzarova T., Valieva S., Isaeva K., Chomakhidze A., Semikina E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vsp.spr-journal.ru/jour/article/view/1364">https://vsp.spr-journal.ru/jour/article/view/1364</self-uri><abstract/><trans-abstract xml:lang="en"/></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Firestein G.S. 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