<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vsp</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы современной педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Current Pediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-5527</issn><issn pub-type="epub">1682-5535</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/vsp.v11i2.233</article-id><article-id custom-type="elpub" pub-id-type="custom">vsp-140</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL OBSERVATIONS</subject></subj-group></article-categories><title-group><article-title>ОПЫТ ПРИМЕНЕНИЯ ЭТАНЕРЦЕПТА ПРИ РАННЕМ ЮВЕНИЛЬНОМ АНКИЛОЗИРУЮЩЕМ СПОНДИЛОАРТРИТЕ</article-title><trans-title-group xml:lang="en"><trans-title>USE OF ETANERCEPT IN JUVENILLE ANKYLOSING SPONDILLO-ARTHRITIS WITH EARLY ONSET</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фетисова</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Fetisova</surname><given-names>A. N.</given-names></name></name-alternatives><email xlink:type="simple">alekatya@ya.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеева</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Alexeeva</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор, заведующая ревматологическим отделением Научного центра здоровья детей РАМН, декан педиатрического факультета Первого МГМУ им. И.М. Сеченова</p></bio><bio xml:lang="en"><p>Ekaterina Iosifovna Alexeeva, PhD, professor, Head of the Pediatric Department of I.M. Sechenov First MSMU, Head of the Rheumatologic Department of SCCH of RAMS</p></bio><email xlink:type="simple">alekatya@ya.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бзарова</surname><given-names>Т. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Bzarova</surname><given-names>T. M.</given-names></name></name-alternatives><email xlink:type="simple">alekatya@ya.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тайбулатов</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Taybulatov</surname><given-names>N. I.</given-names></name></name-alternatives><email xlink:type="simple">alekatya@ya.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Старикова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Starikova</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">alekatya@ya.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аникин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Anikin</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">alekatya@ya.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бекджанян</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bekdzhanyan</surname><given-names>G. A.</given-names></name></name-alternatives><email xlink:type="simple">alekatya@ya.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научный центр здоровья детей РАМН, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Centre of Children Health RAMS, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научный центр здоровья детей РАМН, Москва&#13;
Первый Московский государственный медицинский университет им. И.М. Сеченова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Centre of Children Health RAMS, Moscow&#13;
I.M. Sechenov First Moscow State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Московский научно-исследовательский институт глазных болезней им. Гельмгольца</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The Helmholtz Moscow Research Institute of Eye Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>15</day><month>03</month><year>2012</year></pub-date><volume>11</volume><issue>2</issue><issue-title>Вопросы современной педиатрии</issue-title><fpage>169</fpage><lpage>175</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Фетисова А.Н., Алексеева Е.И., Бзарова Т.М., Тайбулатов Н.И., Старикова А.В., Аникин А.В., Бекджанян Г.А., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Фетисова А.Н., Алексеева Е.И., Бзарова Т.М., Тайбулатов Н.И., Старикова А.В., Аникин А.В., Бекджанян Г.А.</copyright-holder><copyright-holder xml:lang="en">Fetisova A.N., Alexeeva E.I., Bzarova T.M., Taybulatov N.I., Starikova A.V., Anikin A.V., Bekdzhanyan G.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vsp.spr-journal.ru/jour/article/view/140">https://vsp.spr-journal.ru/jour/article/view/140</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>ювенильный анкилозирующий спондилоартрит</kwd><kwd>этанерцепт</kwd><kwd>лечение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>juvenile ankylosing spondillo-arthritis</kwd><kwd>etanercept</kwd><kwd>treatment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Cassidy J. T., Petty R. E., Laxer R. M. et al. Textbook of pediatric rheumatology. 6th ed. Philadelphia: Saunders Elsevier. 2010. 794 p.</mixed-citation><mixed-citation xml:lang="en">Cassidy J. T., Petty R. E., Laxer R. M. et al. Textbook of pediatric rheumatology. 6th ed. Philadelphia: Saunders Elsevier. 2010. 794 p.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Nikishina I. P. Consilium medicum — Consilium medicum. 2006; 8 (2): 20–23.</mixed-citation><mixed-citation xml:lang="en">Nikishina I. P. Consilium medicum — Consilium medicum. 2006; 8 (2): 20–23.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Pepmueller P. H., Moore T. L. Juvenile onset spondylo arthropathies. Curr. Opin. Rheumatol. 2000; 12: 269–273.</mixed-citation><mixed-citation xml:lang="en">Pepmueller P. H., Moore T. L. Juvenile onset spondylo arthropathies. Curr. Opin. Rheumatol. 2000; 12: 269–273.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Prier A. M. Spondyloarthropathies in childhood. Bailiere`s Clin. Rheumatol. 1998; 12: 287–307.</mixed-citation><mixed-citation xml:lang="en">Prier A. M. Spondyloarthropathies in childhood. Bailiere`s Clin. Rheumatol. 1998; 12: 287–307.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Burgos-Vargas R., Pacheco-Tena C., Vazquez-Mellado J. Juvenileonset spondyloarthropathies. Rheum. Dis. Clin. North. Am. 1997; 23: 569–598.</mixed-citation><mixed-citation xml:lang="en">Burgos-Vargas R., Pacheco-Tena C., Vazquez-Mellado J. Juvenileonset spondyloarthropathies. Rheum. Dis. Clin. North. Am. 1997; 23: 569–598.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Nikishina I. P. Yuvenil'nyi ankiloziruyushchii spondiloartrit. Prakticheskoe rukovodstvo po detskim boleznyam. Tom III. Pod obshchei red. V. F. Kokolinoi, A. G. Rumyantseva [Juvenile Ankylosing Spondylitis. Manual on Child Diseases. Volume 3. Edited by V. F. Kokolina, A. G. Rumyantsev]. Moscow, Medpraktika, 2004. pp. 620–649.</mixed-citation><mixed-citation xml:lang="en">Nikishina I. P. Yuvenil'nyi ankiloziruyushchii spondiloartrit. Prakticheskoe rukovodstvo po detskim boleznyam. Tom III. Pod obshchei red. V. F. Kokolinoi, A. G. Rumyantseva [Juvenile Ankylosing Spondylitis. Manual on Child Diseases. Volume 3. Edited by V. F. Kokolina, A. G. Rumyantsev]. Moscow, Medpraktika, 2004. pp. 620–649.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Kuz'mina N. N. Yuvenil'nyi ankiloziruyushchii spondiloartrit. Detskaya revmatologiya. Rukovodstvo dlya vrachei. Pod red. A. A. Baranova, L. K. Bazhenovoi [Juvenile Ankylosing Spondylitis. Pediatric Rheumatology. Guideline. Edited by A. A. Baranov, L. K. Bazhenova]. Moscow, Meditsina, 2002. pp. 141–182.</mixed-citation><mixed-citation xml:lang="en">Kuz'mina N. N. Yuvenil'nyi ankiloziruyushchii spondiloartrit. Detskaya revmatologiya. Rukovodstvo dlya vrachei. Pod red. A. A. Baranova, L. K. Bazhenovoi [Juvenile Ankylosing Spondylitis. Pediatric Rheumatology. Guideline. Edited by A. A. Baranov, L. K. Bazhenova]. Moscow, Meditsina, 2002. pp. 141–182.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Loginova E.Yu. Yuvenil'nyi artrit vo vzrosloi revmatologicheskoi klinike: kliniko-funktsional'naya kharakteristika i iskhody. Avtoref. dis. … kand. med. nauk [Juvenile Arthritis in Adult Rheumatologic Clinical Picture: Clinical and Functional Characteristics, Fate. Author’s abstract]. Moscow, 2001.</mixed-citation><mixed-citation xml:lang="en">Loginova E.Yu. Yuvenil'nyi artrit vo vzrosloi revmatologicheskoi klinike: kliniko-funktsional'naya kharakteristika i iskhody. Avtoref. dis. … kand. med. nauk [Juvenile Arthritis in Adult Rheumatologic Clinical Picture: Clinical and Functional Characteristics, Fate. Author’s abstract]. Moscow, 2001.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Bowyer S., Roettcher P. and the members of the Pediatric Rheumatology Database Research Group. Pediatric rheumatology clinic populations in the United States: results of a 3 year survey. J. Rheumatol. 1996; 23: 1968–1974.</mixed-citation><mixed-citation xml:lang="en">Bowyer S., Roettcher P. and the members of the Pediatric Rheumatology Database Research Group. Pediatric rheumatology clinic populations in the United States: results of a 3 year survey. J. Rheumatol. 1996; 23: 1968–1974.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Towner S. R., Michet C. J. Jr, O’Fallon W. M., Nelson A. M. The epidemiology of juvenile arthritis in Rochester, Minnesota 1960– 1979. Arthritis Rheum. 1983; 26: 1208–1213.</mixed-citation><mixed-citation xml:lang="en">Towner S. R., Michet C. J. Jr, O’Fallon W. M., Nelson A. M. The epidemiology of juvenile arthritis in Rochester, Minnesota 1960– 1979. Arthritis Rheum. 1983; 26: 1208–1213.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Andersson Gare B. Juvenile arthritis: who gets it, where and when? A review of current data on incidence and prevalence. Clin. Exp. Rheumatol. 1999; 17: 367–374.</mixed-citation><mixed-citation xml:lang="en">Andersson Gare B. Juvenile arthritis: who gets it, where and when? A review of current data on incidence and prevalence. Clin. Exp. Rheumatol. 1999; 17: 367–374.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Manners P. J., Bower C. Worldwide prevalence of juvenile arthritis: why does it vary so much? J. Rheumatol. 2002; 29: 1520–1530.</mixed-citation><mixed-citation xml:lang="en">Manners P. J., Bower C. Worldwide prevalence of juvenile arthritis: why does it vary so much? J. Rheumatol. 2002; 29: 1520–1530.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Bochkova A. G. Consilium medicum — Consilium medicum. 2006; 8 (2).</mixed-citation><mixed-citation xml:lang="en">Bochkova A. G. Consilium medicum — Consilium medicum. 2006; 8 (2).</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Fearon U., Veale D. J. Pathogenesis of psoriatic arthritis. Clin. Exp. Dermatol. 2001; 26: 333–337.</mixed-citation><mixed-citation xml:lang="en">Fearon U., Veale D. J. Pathogenesis of psoriatic arthritis. Clin. Exp. Dermatol. 2001; 26: 333–337.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Kalden J. R. Emerging role of anti-tumor necrosis factor therapy in rheumatic diseases. Arthritis Res. 2002; 4 (Suppl. 2): 534–540.</mixed-citation><mixed-citation xml:lang="en">Kalden J. R. Emerging role of anti-tumor necrosis factor therapy in rheumatic diseases. Arthritis Res. 2002; 4 (Suppl. 2): 534–540.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Mease P., Kivitz A. J., Burch F. X. et al. Etanercept treatment of psoriatic arthritis: sarety, efficacy, and effect on disease progression. Arthritis Rheum. 2004; 50: 2264–2272.</mixed-citation><mixed-citation xml:lang="en">Mease P., Kivitz A. J., Burch F. X. et al. Etanercept treatment of psoriatic arthritis: sarety, efficacy, and effect on disease progression. Arthritis Rheum. 2004; 50: 2264–2272.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Beutler B. A. The role of tumor necrosis factor in health and disease. J. Rheumatol. 1999; 26 (Suppl. 57): 16–21.</mixed-citation><mixed-citation xml:lang="en">Beutler B. A. The role of tumor necrosis factor in health and disease. J. Rheumatol. 1999; 26 (Suppl. 57): 16–21.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Granfors K., Marker-Hermann E., De Kayser F. The cutting edge of spondiloarthropathy research in the millennium. Arthritis Rheum. 2002; 46 (3): 606–613.</mixed-citation><mixed-citation xml:lang="en">Granfors K., Marker-Hermann E., De Kayser F. The cutting edge of spondiloarthropathy research in the millennium. Arthritis Rheum. 2002; 46 (3): 606–613.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Mease P., Antoni C. E. Psoriatic arthritis treatment: biological response modifiers. Ann. Rheum. Dis. 2005; 64 (Suppl. 2): 78–82.</mixed-citation><mixed-citation xml:lang="en">Mease P., Antoni C. E. Psoriatic arthritis treatment: biological response modifiers. Ann. Rheum. Dis. 2005; 64 (Suppl. 2): 78–82.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Badokin V. C. Vrach — Physician. 2005; 5: 48–52.</mixed-citation><mixed-citation xml:lang="en">Badokin V. C. Vrach — Physician. 2005; 5: 48–52.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Reed M. R., Taylor A. L. Tumor necrosis factor inhibitors in ankylosing spondylitis. Intern. Med. J. 2008; 38 (10): 781–789.</mixed-citation><mixed-citation xml:lang="en">Reed M. R., Taylor A. L. Tumor necrosis factor inhibitors in ankylosing spondylitis. Intern. Med. J. 2008; 38 (10): 781–789.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Haibel H., Song I. H., Rudwaleit M. et al. Multicenter open-label study with infliximab in active ankylosing spondylitis over 28 week in daily practice. Clin. Exp. Rheumatol. 2008; 26 (2): 247–252.</mixed-citation><mixed-citation xml:lang="en">Haibel H., Song I. H., Rudwaleit M. et al. Multicenter open-label study with infliximab in active ankylosing spondylitis over 28 week in daily practice. Clin. Exp. Rheumatol. 2008; 26 (2): 247–252.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Braun J., Deodhar A., Dijkmans B. et al. Efficacy and safety of infliximab in patients with ankylosing spondylitis over a two-year period. Arthritis Rheum. 2008; 59 (9): 1270–1278.</mixed-citation><mixed-citation xml:lang="en">Braun J., Deodhar A., Dijkmans B. et al. Efficacy and safety of infliximab in patients with ankylosing spondylitis over a two-year period. Arthritis Rheum. 2008; 59 (9): 1270–1278.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Griffoul I., Giraudeau B., Mulleman D. et al. Infliximab for treating axial spondylarthropathy in everyday practice. Joint Bone Spine. 2009; 76 (1): 39–43.</mixed-citation><mixed-citation xml:lang="en">Griffoul I., Giraudeau B., Mulleman D. et al. Infliximab for treating axial spondylarthropathy in everyday practice. Joint Bone Spine. 2009; 76 (1): 39–43.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Rumyantseva O. A. Nauchno-prakticheskaya revmatologiya — Reseach and practical rheumatology. 2006; 4: 11–19.</mixed-citation><mixed-citation xml:lang="en">Rumyantseva O. A. Nauchno-prakticheskaya revmatologiya — Reseach and practical rheumatology. 2006; 4: 11–19.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Kozlova A. L., Alekseeva E. I., Valieva S.I. Voprosi sovremennoi pediatrii — Current Pediatrics. 2009; 8 (2): 20–26.</mixed-citation><mixed-citation xml:lang="en">Kozlova A. L., Alekseeva E. I., Valieva S.I. Voprosi sovremennoi pediatrii — Current Pediatrics. 2009; 8 (2): 20–26.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Alekseeva E. I., Kozlova A. L., Valieva S. I. Voprosi sovremennoi pediatrii — Current Pediatrics. 2010; 9 (2): 23–31.</mixed-citation><mixed-citation xml:lang="en">Alekseeva E. I., Kozlova A. L., Valieva S. I. Voprosi sovremennoi pediatrii — Current Pediatrics. 2010; 9 (2): 23–31.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Alekseeva E. I., Alekseeva A. M., Valieva S. I. etc. Voprosi sovremennoi pediatrii — Current Pediatrics. 2008; 7 (2): 42–54.</mixed-citation><mixed-citation xml:lang="en">Alekseeva E. I., Alekseeva A. M., Valieva S. I. etc. Voprosi sovremennoi pediatrii — Current Pediatrics. 2008; 7 (2): 42–54.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Alekseeva E. I., Valieva S. I., Denisova R. V. Voprosi sovremennoi pediatrii — Current Pediatrics. 2008; 7 (5): 51–57.</mixed-citation><mixed-citation xml:lang="en">Alekseeva E. I., Valieva S. I., Denisova R. V. Voprosi sovremennoi pediatrii — Current Pediatrics. 2008; 7 (5): 51–57.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Moreland L. W., Schiff M. H., Baumgarthner S. W. et al. Etanercept therapy in rheumatoid arthritis. Ann. Int. Med. 1999; 130: 478–486.</mixed-citation><mixed-citation xml:lang="en">Moreland L. W., Schiff M. H., Baumgarthner S. W. et al. Etanercept therapy in rheumatoid arthritis. Ann. Int. Med. 1999; 130: 478–486.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Moreland L. W., Scott M. D., Baumgarther W. et al. Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. N. Engl. J. Med. 1997; 337: 141–147.</mixed-citation><mixed-citation xml:lang="en">Moreland L. W., Scott M. D., Baumgarther W. et al. Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. N. Engl. J. Med. 1997; 337: 141–147.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Prince F. H., Twilt M., Ten Cate R. et al. Long-term follow-up on effectiveness and safety of etanercept in JIA: the Dutch national register. Ann. Rheum. Dis. 2008; 68 (5): 635–641.</mixed-citation><mixed-citation xml:lang="en">Prince F. H., Twilt M., Ten Cate R. et al. Long-term follow-up on effectiveness and safety of etanercept in JIA: the Dutch national register. Ann. Rheum. Dis. 2008; 68 (5): 635–641.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Horneff G., De Bock F., Foeldvari I. et al. Safety and efficacy of combination of Etanercept and Methotrexate compared to treatment with Etanercept only in patients with juvenile idiopathic arthritis (JIA). Preliminary data from the German JIA Registry. Ann. Rheum. Dis. 2008; 68 (4): 519–525.</mixed-citation><mixed-citation xml:lang="en">Horneff G., De Bock F., Foeldvari I. et al. Safety and efficacy of combination of Etanercept and Methotrexate compared to treatment with Etanercept only in patients with juvenile idiopathic arthritis (JIA). Preliminary data from the German JIA Registry. Ann. Rheum. Dis. 2008; 68 (4): 519–525.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Nielsen S., Ruperto N., Gerloni V. et al. Preliminary evidence that etanercept may reduce radiographic progression in juvenile idiopathic arthritis. Clin. Exp. Rheumatol. 2008; 26 (4): 688–692.</mixed-citation><mixed-citation xml:lang="en">Nielsen S., Ruperto N., Gerloni V. et al. Preliminary evidence that etanercept may reduce radiographic progression in juvenile idiopathic arthritis. Clin. Exp. Rheumatol. 2008; 26 (4): 688–692.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Lovell D. J., Reiff A., Ilowite N. T. et al. Safety and efficacy of up to eight years of continuous etanercept therapy in patients with juvenile rheumatoid arthritis. Arthritis Rheum. 2008; 58 (5): 1496–1504.</mixed-citation><mixed-citation xml:lang="en">Lovell D. J., Reiff A., Ilowite N. T. et al. Safety and efficacy of up to eight years of continuous etanercept therapy in patients with juvenile rheumatoid arthritis. Arthritis Rheum. 2008; 58 (5): 1496–1504.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Robinson R. F., Nahata M. C., Hayes J. R. et al. Quality-of-Life Measurements in Juvenile Rheumatoid Arthritis Patients Treated with Etanercept. Clin. Drug. Investig. 2003; 23 (8): 511–518.</mixed-citation><mixed-citation xml:lang="en">Robinson R. F., Nahata M. C., Hayes J. R. et al. Quality-of-Life Measurements in Juvenile Rheumatoid Arthritis Patients Treated with Etanercept. Clin. Drug. Investig. 2003; 23 (8): 511–518.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Palazzi C., D’Angelo S., Cantini F. et al. Etanercept in spondylo arthropathies. Part I: current evidence of efficacy. Clin. Exp. Rheumatol. 2011; 29 (5): 858–64.</mixed-citation><mixed-citation xml:lang="en">Palazzi C., D’Angelo S., Cantini F. et al. Etanercept in spondylo arthropathies. Part I: current evidence of efficacy. Clin. Exp. Rheumatol. 2011; 29 (5): 858–64.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Navarro-Sarabia F., Fernandez-Sueiro J. L., Torre-Alonso J. C., Grata cos J. et al. High-dose etanercept in ankylosing spondylitis: results of a 12-week randomized, double blind, controlled multicentre study (LOADET study). Rheumatology (Oxford). 2011; 50 (10): 1828–37.</mixed-citation><mixed-citation xml:lang="en">Navarro-Sarabia F., Fernandez-Sueiro J. L., Torre-Alonso J. C., Grata cos J. et al. High-dose etanercept in ankylosing spondylitis: results of a 12-week randomized, double blind, controlled multicentre study (LOADET study). Rheumatology (Oxford). 2011; 50 (10): 1828–37.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Braun J., van der Horst-Bruinsma I. E., Huang F., BurgosVargas R. et al. Clinical efficacy and safety of etanercept versus sulfasalazine in patients with ankylosing spondylitis: a randomized, double-blind trial. Arthritis Rheum. 2011; 63 (6): 1543–51.</mixed-citation><mixed-citation xml:lang="en">Braun J., van der Horst-Bruinsma I. E., Huang F., BurgosVargas R. et al. Clinical efficacy and safety of etanercept versus sulfasalazine in patients with ankylosing spondylitis: a randomized, double-blind trial. Arthritis Rheum. 2011; 63 (6): 1543–51.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
