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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vsp</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы современной педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Current Pediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-5527</issn><issn pub-type="epub">1682-5535</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">vsp-1409</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В ПОМОЩЬ  ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>A DOCTOR’S AID</subject></subj-group></article-categories><title-group><article-title>БЕЗОПАСНОСТЬ ПРИМЕНЕНИЯ ИНТЕРФЕРОНА БЕТА-1А ДЛЯ ПОДКОЖНОГО ВВЕДЕНИЯ У ДЕТЕЙ И ПОДРОСТКОВ С РАССЕЯННЫМ СКЛЕРОЗОМ</article-title><trans-title-group xml:lang="en"><trans-title>SAFETY OF INTERFERON BETA 1A FOR A SUBCUTANEOUS ADMINISTRATION IN CHILDREN AND ADOLESCENTS WITH DISSEMINATED SCLEROSIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Быкова</surname><given-names>О.В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bykova</surname><given-names>O.V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Платонова</surname><given-names>А.Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Platonova</surname><given-names>A.N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гольцова</surname><given-names>Н.В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gol'tsova</surname><given-names>N.V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузенкова</surname><given-names>Л.М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuzenkova</surname><given-names>L.M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бойко</surname><given-names>А.Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Boiko</surname><given-names>A.N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научный центр здоровья детей РАМН, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Российский государственный медицинский университет, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Chair of Neurology and Neurosurgery, Russian State Medical University, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>05</day><month>11</month><year>2015</year></pub-date><volume>7</volume><issue>3</issue><issue-title>Вопросы современной педиатрии</issue-title><fpage>108</fpage><lpage>112</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Быкова О., Платонова А., Гольцова Н., Кузенкова Л., Бойко А., 2008</copyright-statement><copyright-year>2008</copyright-year><copyright-holder xml:lang="ru">Быкова О., Платонова А., Гольцова Н., Кузенкова Л., Бойко А.</copyright-holder><copyright-holder xml:lang="en">Bykova O., Platonova A., Gol'tsova N., Kuzenkova L., Boiko A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vsp.spr-journal.ru/jour/article/view/1409">https://vsp.spr-journal.ru/jour/article/view/1409</self-uri><abstract/><trans-abstract xml:lang="en"/></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Rosati G. The prevalence of multiple sclerosis in the world: an update. Neurol. Science. 2001; 22: 117–139.</mixed-citation><mixed-citation xml:lang="en">Rosati G. The prevalence of multiple sclerosis in the world: an update. Neurol. Science. 2001; 22: 117–139.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Sadovnick A.D., Ebers G.C. Epidemiology of multiple sclerosis: a critical overview. Can J. Neurol. Sci. 1993; 20: 17–29.</mixed-citation><mixed-citation xml:lang="en">Sadovnick A.D., Ebers G.C. Epidemiology of multiple sclerosis: a critical overview. Can J. Neurol. Sci. 1993; 20: 17–29.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Boiko F., Vorobeychik G., Paty D. et al. Early onset of multiple sclerosis: a longitudinal study. Neurology. 2002; 59 (7): 1006–1010.</mixed-citation><mixed-citation xml:lang="en">Boiko F., Vorobeychik G., Paty D. et al. Early onset of multiple sclerosis: a longitudinal study. Neurology. 2002; 59 (7): 1006–1010.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Ghezzi A., Pozzilli C., Liguori M. et al. Prospective study of multiple sclerosis with early onset? Multiple sclerosis. 2002; 8 (2): 115–118.</mixed-citation><mixed-citation xml:lang="en">Ghezzi A., Pozzilli C., Liguori M. et al. Prospective study of multiple sclerosis with early onset? Multiple sclerosis. 2002; 8 (2): 115–118.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Pinhas-Hamiel O., Sarova–Pinhas I., Achrion A. Multiple sclerosis in childhood and adolescence: Clinical features and management. Paediatr. Drugs. 2001; 3 (5): 329–336.</mixed-citation><mixed-citation xml:lang="en">Pinhas-Hamiel O., Sarova–Pinhas I., Achrion A. Multiple sclerosis in childhood and adolescence: Clinical features and management. Paediatr. Drugs. 2001; 3 (5): 329–336.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Shaw C.M., Alvord E.C. Multiple sclerosis beginning in infancy. J. Child. Neurology. 1987; 2: 252–256.</mixed-citation><mixed-citation xml:lang="en">Shaw C.M., Alvord E.C. Multiple sclerosis beginning in infancy. J. Child. Neurology. 1987; 2: 252–256.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Waubant E., Hietpas J., Stewart T. et al. Interferon beta–1ᾳ in children with multiple sclerosis is well tolerated. Neuropediatrics. 2001; 32 (4): 211–213.</mixed-citation><mixed-citation xml:lang="en">Waubant E., Hietpas J., Stewart T. et al. Interferon beta–1ᾳ in children with multiple sclerosis is well tolerated. Neuropediatrics. 2001; 32 (4): 211–213.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Быкова О.В., Маслова О.И., Гусева М.Р. и др. Рассеянный склероз у детей и подростков: история изучения проблемы и современный опыт иммуномодулирующего лечения. Журнал неврологии и психиатрии. 2004; 4: 4–10.</mixed-citation><mixed-citation xml:lang="en">Быкова О.В., Маслова О.И., Гусева М.Р. и др. Рассеянный склероз у детей и подростков: история изучения проблемы и современный опыт иммуномодулирующего лечения. Журнал неврологии и психиатрии. 2004; 4: 4–10.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Bosley E.B., Capildeo R. Early use of interferon  in patients with multiple sclerosis. Clinical Practice. 2002; Suppl.131: 17–22.</mixed-citation><mixed-citation xml:lang="en">Bosley E.B., Capildeo R. Early use of interferon  in patients with multiple sclerosis. Clinical Practice. 2002; Suppl.131: 17–22.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Panitch H., Goodin D.S., Francis G. et al. Randomized, comparative study of interferon-b-1a treatment regimens in MS. The Evidence Trial. Neurology. 2002; 59: 1496–1506.</mixed-citation><mixed-citation xml:lang="en">Panitch H., Goodin D.S., Francis G. et al. Randomized, comparative study of interferon-b-1a treatment regimens in MS. The Evidence Trial. Neurology. 2002; 59: 1496–1506.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Durelli L., Ferrero B., Ghezzi A. et al. The Independent Comparison of Interferon (INCOMIN) Trial: a multicenter randomized trial comparing clinical and MRI efficacy of IFN beta-1a and beta-1b in multiple sclerosis (abstract). Neurology. 2001; 56 (Suppl. 3): 148.</mixed-citation><mixed-citation xml:lang="en">Durelli L., Ferrero B., Ghezzi A. et al. The Independent Comparison of Interferon (INCOMIN) Trial: a multicenter randomized trial comparing clinical and MRI efficacy of IFN beta-1a and beta-1b in multiple sclerosis (abstract). Neurology. 2001; 56 (Suppl. 3): 148.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Fischer J.S., Rudick R.A., Cutter G.R. et al. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult. Scler. 1999; 5: 244–250.</mixed-citation><mixed-citation xml:lang="en">Fischer J.S., Rudick R.A., Cutter G.R. et al. The Multiple Sclerosis Functional Composite Measure (MSFC): an integrated approach to MS clinical outcome assessment. National MS Society Clinical Outcomes Assessment Task Force. Mult. Scler. 1999; 5: 244–250.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Cборник стандартов оказания дорогостоящей (высокотехнологической) медицинской помощи Минздравсоцразвития России.</mixed-citation><mixed-citation xml:lang="en">Cборник стандартов оказания дорогостоящей (высокотехнологической) медицинской помощи Минздравсоцразвития России.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
