References

vsp

Вопросы современной педиатрии

Current Pediatrics

1682-55271682-5535

Издательство «ПедиатрЪ»

10.15690/vsp.v15i2.1531

vsp-1604

Research Article

ОБЗОРЫ ЛИТЕРАТУРЫ

LITERATURE REVIEW

Роль диффузионной тензорной магнитно-резонансной томографии и трактографии в диагностике структурных повреждений головного мозга у детей с церебральными параличами

The Role of Diffusion-Tensor Magnetic Resonance Imaging and Tractography in the Diagnosis of Structural Brain Disorders in Children with Cerebral Palsy

Ермолина

Ю. В.

Ermolina

Yu. V.

аспирант отделения восстановительного лечения детей с болезнями нервной системы НИИ педиатрии Научного центра здоровья детей, Адрес: 119991, Москва, Ломоносовский пр-т, д. 2, стр. 3, тел.: +7 (499) 134-02-76

ermolina_jv@mail.ru

Намазова-Баранова

Л. С.

Namazova-Baranova

L. S.

Мамедьяров

А. М.

Mamedyarov

A. M.

Аникин

А. В.

Anikin

A. V.

Маслова

О. И.

Maslova

O. I.

Научный центр здоровья детей, Москва, Российская ФедерацияРоссияScientific Centre of Children’s Health, Moscow, Russian FederationRussian Federation

Научный центр здоровья детей, Москва, Российская Федерация Первый Московский государственный медицинский университет им. И.М. Сеченова, Москва, Российская Федерация Российский национальный исследовательский медицинский университет им. Н.И. Пирогова, Москва, Российская ФедерацияРоссияScientific Centre of Children’s Health, Moscow, Russian Federation Pirogov Russian National Research Medical University, Moscow, Russian Federation I.M. Sechenov First Moscow State Medical University, Moscow, Russian FederationRussian Federation

2016

01062016

152141147

2016

Ермолина Ю.В., Намазова-Баранова Л.С., Мамедьяров А.М., Аникин А.В., Маслова О.И.

Ermolina Y.V., Namazova-Baranova L.S., Mamedyarov A.M., Anikin A.V., Maslova O.I.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://vsp.spr-journal.ru/jour/article/view/1604

В течение последних десятилетий благодаря активному внедрению в клиническую практику и научные исследования методов нейровизуализации стала возможной прижизненная оценка структурно-функционального состояния нервной системы у детей всех возрастов, начиная с внутриутробного периода развития. Данные, полученные при нейровизуализационных исследованиях, существенно дополнили традиционные представления, основанные на применении классических морфологических методов. С помощью диффузионной тензорной магнитно-резонансной томографии и трактографии стали возможными проведение комплексных структурно-функциональных исследований, изучение основных этапов созревания головного мозга в динамике, а также сопоставление морфологических данных с особенностями психоречевого и двигательного развития ребенка и клинико-нейровизуализационные сравнения. В статье описаны современные возможности диагностики микроструктурных повреждений головного мозга с помощью диффузионной тензорной трактографии у детей с постгипоксическими состояниями и церебральными параличами. Показано, что выявленные изменения коррелируют с клинической картиной заболевания.

In the past few decades, the active introduction of neuroimaging methods into clinical practice and research allowed us to assess the in vivo structural and functional state of the nervous system in children of all ages, from prenatal period of the development. The data obtained during neuroimaging studies significantly complemented the traditional view, based on the application of classical morphological methods. Using diffusion-tensor magnetic resonance imaging and tractography, it became possible to conduct comprehensive structural and functional studies, to study the main stages of the brain maturation in dynamics, and to compare the morphological data with peculiarities of psycho-verbal and motor development of a child, as well as to conduct clinical and neuroimaging comparison. The article describes modern possibilities of diagnostics of microstructural damages of the brain using diffusion-tensor tractography in children with post-hypoxic conditions and cerebral palsy. It is shown that the revealed changes correlate with aspect of the disease.

детимагнитно-резонансная томографиядиффузионно-тензорная трактографиядетский церебральный параличмиелинизацияперивентрикулярные поврежденияфракционная анизотропияструктурные нарушения головного мозга

childrenmagnetic resonance imagingdiffusion-tensor tractographyinfantile cerebral palsymyelinationperiventricular lesionsfractional anisotropystructural brain disorders

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The authors declare that there are no conflicts of interest present.