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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vsp</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы современной педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Current Pediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-5527</issn><issn pub-type="epub">1682-5535</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/vsp.v15i3.1571</article-id><article-id custom-type="elpub" pub-id-type="custom">vsp-1646</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МНЕНИЕ ПО ПРОБЛЕМЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXPERT OPINION</subject></subj-group></article-categories><title-group><article-title>Применение блокаторов фактора некроза опухоли  в терапии ревматоидного артрита. Комментарии к результатам метаанализа рандомизированных испытаний N. Graudal и соавт.: окончательные выводы или почва для размышлений?</article-title><trans-title-group xml:lang="en"><trans-title>Administration of TNF- Inhibitors for Rheumatoid Arthritis Therapy. Comments to the Results of a Meta-Analysis of Randomized Trials by N. Graudal et al.: Final or Thought Provoking Conclusions?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1180-8086</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Костик</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kostik</surname><given-names>Mikhail M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, доцент кафедры госпитальной педиатрии Санкт-Петербургского государственного педиатрического медицинского университета Адрес: 194100, Санкт-Петербург, ул. Литовская, д. 2, тел.: +7 (812) 416-52-98</p></bio><email xlink:type="simple">kost-mikhail@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Санкт-Петербургский государственный педиатрический медицинский университет, Санкт-Петербург, Российская Федерация</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint-Petersburg State Pediatric Medical University, Saint-Petersburg, Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>10</day><month>08</month><year>2016</year></pub-date><volume>15</volume><issue>3</issue><fpage>315</fpage><lpage>317</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Костик М.М., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Костик М.М.</copyright-holder><copyright-holder xml:lang="en">Kostik M.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vsp.spr-journal.ru/jour/article/view/1646">https://vsp.spr-journal.ru/jour/article/view/1646</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Dickersin K, Berlin JA. 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