vspВопросы современной педиатрииCurrent Pediatrics1682-55271682-5535Издательство «ПедиатрЪ»10.15690/vsp.v16i3.1730vsp-1756Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEWГАСТРОИНТЕСТИНАЛЬНАЯ ПИЩЕВАЯ АЛЛЕРГИЯ У ДЕТЕЙGASTROINTESTINAL FOOD ALLERGY IN CHILDRENhttps://orcid.org/0000-0002-3056-403XМакароваС. Г.MakarovaSvetlana G.

Макарова Светлана Геннадиевна - доктор медицинских наук, профессор, заведующая отделом профилактической педиатрии ННПЦЗД.

119991, Москва, Ломоносовский пр-т, д. 2, стр. 1, тел.: +7 (495) 967-14-20 (доб. 16-03)

Moscow

sm27@yandex.ruhttps://orcid.org/0000-0002-2209-7531Намазова-БарановаЛ. С.Namazova-BaranovaLeyla S.

Москва

Moscow

https://orcid.org/0000-0001-7398-0562ВишнёваЕ. А.VishnevaElena A.

Москва

https://orcid.org/0000-0002-3056-403XЕрешкоО. А.EreshkoOksana A.

Москва

Moscow

https://orcid.org/0000-0001-6658-0624ГордееваИ. Г.GordeevaIrina G.

Москва

Moscow

Национальный научно-практический центр здоровья детейРоссияNational Scientific and Practical Center of Children’s HealthRussian FederationНациональный научно-практический центр здоровья детей; Российский национальный исследовательский медицинский университет им. Н.И. ПироговаРоссияNational Scientific and Practical Center of Children’s Health; Pirogov Russian National Research Medical UniversityRussian FederationНациональный научно-практический центр здоровья детей; Первый Московский государственный медицинский университет им. И.М. СеченоваРоссияNational Scientific and Practical Center of Children’s Health; Sechenov First Moscow State Medical UniversityRussian Federation201715072017163202212Copyright © Макарова С.Г., Намазова-Баранова Л.С., Вишнёва Е.А., Ерешко О.А., Гордеева И.Г., 20172017Макарова С.Г., Намазова-Баранова Л.С., Вишнёва Е.А., Ерешко О.А., Гордеева И.Г.Makarova S.G., Namazova-Baranova L.S., Vishneva E.A., Ereshko O.A., Gordeeva I.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vsp.spr-journal.ru/jour/article/view/1756

В последние  годы наблюдается  значительный  рост распространенности  пищевой аллергии.  Патологические  состояния, связанные  с нарушением толерантности к пище, становятся  все  более  актуальной  проблемой  педиатрии. По данным разных исследователей, аллергическое поражение желудочно-кишечного тракта встречается у 25–50% больных с такой распространенной патологией, как аллергия  на белки коровьего молока. Тяжесть заболеваний, связанных с пищевой аллергией,  а также их прогноз во многом зависят от ранней диагностики и адекватной лечебной тактики. Трудности и ошибки диагностики гастроинтестинальной  пищевой аллергии  связаны как с субъективными, так и с объективными причинами, в первую очередь с тем, что гастроинтестинальные  реакции на пищу часто носят отсроченный характер и протекают по не-IgE-опосредованному типу. В статье описаны клинические формы гастроинтестинальной пищевой аллергии  согласно существующей классификации,  даны диагностические алгоритмы и современные, основанные на доказательной медицине и соответствующие международным  согласительным  документам подходы к дифференциальной диагностике заболевания.

In recent years, there has been a significant increase in the prevalence  of food allergies. Pathological conditions associated  with a food intolerance are becoming an increasingly urgent problem of pediatrics. According to different researchers, allergic lesions of the gastrointestinal tract occurs in 25–50% of patients with such common pathology as an allergy to cow's milk proteins. The severity of diseases  associated  with food allergies and their prognosis  depend largely on early diagnosis and adequate treatment. Difficulties and errors  in the diagnosis  of gastrointestinal  food allergies  are associated  with both subjective  and objective  reasons,  primarily due to the fact that gastrointestinal  reactions to food are often delayed and non-IgE-mediated. The article describes clinical forms of gastrointestinal food allergy according to the existing classification. Diagnostic algorithms and modern approaches  to differential diagnosis of disease based on evidence-based  medicine and corresponding to international consensus papers are given.

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The authors declare that there are no conflicts of interest present.