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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vsp</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы современной педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Current Pediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-5527</issn><issn pub-type="epub">1682-5535</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/vsp.v17i3.1894</article-id><article-id custom-type="elpub" pub-id-type="custom">vsp-1905</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКОЕ НАБЛЮДЕНИЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL OBSERVATIONS</subject></subj-group></article-categories><title-group><article-title>СЛУЧАЙ РАННЕГО РАЗВИТИЯ АТОПИЧЕСКОГО ДЕРМАТИТА У РЕБЕНКА НА ГРУДНОМ ВСКАРМЛИВАНИИ</article-title><trans-title-group xml:lang="en"><trans-title>A CASE OF THE EARLY DEVELOPMENT OF ATOPIC DERMATITIS IN A NURSING INFANT</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4955-0121</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Турти</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Turti</surname><given-names>Tatiana V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Турти Татьяна Владимировна - доктор медицинских наук, заведующая отделом организации и проведения научно-исследовательских работ и клинических исследований.</p><p>119991, Москва, Ломоносовский пр-т, д. 2, стр. 1,  тел.: +7 (499) 134-07-45</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">turti@nczd.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бокучава</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Bokuchava</surname><given-names>Ekaterinа G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Илларионов</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Illarionov</surname><given-names>Alexey S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Селиванова</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Selivanova</surname><given-names>Anastasiya G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр здоровья детей; Российский национальный исследовательский медицинский университет имени Н.И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center of Children’s Health; Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр здоровья детей</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center of Children’s Health</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет имени Н.И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>17</day><month>07</month><year>2018</year></pub-date><volume>17</volume><issue>3</issue><fpage>244</fpage><lpage>249</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Турти Т.В., Бокучава Е.Г., Илларионов А.С., Селиванова А.Г., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Турти Т.В., Бокучава Е.Г., Илларионов А.С., Селиванова А.Г.</copyright-holder><copyright-holder xml:lang="en">Turti T.V., Bokuchava E.G., Illarionov A.S., Selivanova A.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vsp.spr-journal.ru/jour/article/view/1905">https://vsp.spr-journal.ru/jour/article/view/1905</self-uri><abstract><sec><title>Обоснование</title><p>Обоснование. Раннее (в первые месяцы жизни) формирование атопического статуса и развитие аллергии — не редкие в практике педиатра патологические состояния, требующие достаточно изученных и методически обоснованных мероприятий по организации первичной/вторичной профилактики.</p><p>Описание клинического случая. Родители обратились с жалобами на распространенные высыпания на коже и беспокойный ночной сон у ребенка с двухмесячного возраста. Отягощенный аллергологический анамнез ребенка прослеживался по женской линии (пищевая аллергия у матери, сестры, бабушки по материнской линии). Перинатальный период осложнен острой респираторной инфекцией в III триместре, а также алиментарными предпочтениями матери (потребление козьего и цельного коровьего молока). Позднее (на 5-е сут жизни) прикладывание к груди, вскармливание смесью на основе белка коровьего молока, проживание рядом с промышленным предприятием, предпочтение продуктов с высоким сенсибилизирующим потенциалом матерью не только в период беременности, но и грудного вскармливания, вероятно, стали причиной раннего формирования атопического статуса — сухости кожи, распространенных высыпаний в виде папул, микровезикул на коже щек, бедер, голеней, следов расчесов, серозно-кровянистых корочек, выявленных объективно при поступлении в стационар. Оценка по шкале SCORAD соответствовала тяжелому течению атопического дерматита. Технология ImmunoCAP выявила высокие титры антител к ряду продуктов, в том числе белкам коровьего молока и куриного яйца. На основании результатов исследований ребенку разработан лечебный рацион, нацеленный на вторичную профилактику аллергических болезней, в том числе респираторной аллергии.</p></sec><sec><title>Заключение</title><p>Заключение. Описан случай раннего (с 2 мес) формирования атопического статуса с развитием атопического дерматита, вызванного поливалентной пищевой сенсибилизацией. Ребенку назначен лечебный рацион, содержащий продукты с низким сенсибилизирующим потенциалом. Ожидается, что такой рацион предупредит прогрессирование аллергической болезни.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. The early (in the first months of life) formation of atopic status and the development of allergies are not uncommon pathological conditions in a pediatrician's practice, requiring sufficiently studied and theoretically grounded measures for the organization of primary/secondary prevention.</p></sec><sec><title>Case Report</title><p>Case Report. The parents visited a doctor with complaints of widespread skin rashes and troubled night sleep in a child from the age of two months. A burdened history of allergies of the child was traced through the female lineage (food allergy in the mother, maternal sister and grandmother). The perinatal period is complicated by acute respiratory infection in the third trimester and by maternal nutritional preferences (consumption of goat's and whole cow's milk). The delayed (on the 5th day of life) breastfeeding initiation, feeding with cow's milk-based formula, living next to an industrial enterprise, maternal choices of products with a high sensitizing potential not only during pregnancy but also during breastfeeding probably caused the early formation of atopic status — dry skin, widespread papular rash, microvesicles on the cheeks, hips, shins, scratching traces, serous-bloody crusts objectively defined at admission. The SCORAD scores corresponded to severe atopic dermatitis. The ImmunoCAP technology revealed high antibody titres to a number of products, including cow's milk and chicken egg proteins. Based on the findings, a therapeutic diet aimed at secondary prevention of allergic diseases, including respiratory allergies, was developed for the child.</p></sec><sec><title>Conclusion</title><p>Conclusion. A case of the early (from 2 months) formation of atopic status with the development of atopic dermatitis caused by polyvalent food sensitization is described. A therapeutic diet containing products with a low sensitizing potential was prescribed for the child. The suggested therapy including the diet should prevent the progression of an allergic disease.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>новорожденный</kwd><kwd>младенец</kwd><kwd>пищевая аллергия</kwd><kwd>высокий риск</kwd><kwd>профилактика</kwd><kwd>иммуногенность</kwd><kwd>прикорм</kwd><kwd>клинический случай</kwd></kwd-group><kwd-group xml:lang="en"><kwd>newborn</kwd><kwd>infant</kwd><kwd>food allergy</kwd><kwd>high risk</kwd><kwd>prevention</kwd><kwd>immunogenicity</kwd><kwd>complementary feeding</kwd><kwd>clinical case</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">ПРОГРЕСС, АО</funding-statement><funding-statement xml:lang="en">PROGRESS JSC</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Pawankar R. Allergic diseases and asthma: a global public health concern and a call to action. 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