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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vsp</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы современной педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Current Pediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-5527</issn><issn pub-type="epub">1682-5535</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/vsp.v17i4.1917</article-id><article-id custom-type="elpub" pub-id-type="custom">vsp-1921</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НЕПРЕРЫВНОЕ ПРОФЕССИОНАЛЬНОЕ ОБРАЗОВАНИЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PROFESSIONAL DEVELOPMENT</subject></subj-group></article-categories><title-group><article-title>Хордома: этиология, патогенез, диагностика, лечение</article-title><trans-title-group xml:lang="en"><trans-title>Chordoma: Etiology, Pathogenesis, Diagnosis, Treatment</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Травкина</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Travkina</surname><given-names>Julia V.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4295-7436</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жевак</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhevak</surname><given-names>Tatiana N.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0151-9114</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Литвицкий</surname><given-names>П. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Litvitsky</surname><given-names>Peter F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Литвицкий Пётр Францевич, доктор медицинских наук, профессор, заведующий кафедрой патофизиологии</p><p>119992, Москва, ул. Трубецкая, д. 8</p></bio><bio xml:lang="en"/><email xlink:type="simple">litvicki@mma.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sechenov First Moscow State Medical University (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>03</day><month>10</month><year>2018</year></pub-date><volume>17</volume><issue>4</issue><fpage>266</fpage><lpage>271</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Травкина Ю.В., Жевак Т.Н., Литвицкий П.Ф., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Травкина Ю.В., Жевак Т.Н., Литвицкий П.Ф.</copyright-holder><copyright-holder xml:lang="en">Travkina J.V., Zhevak T.N., Litvitsky P.F.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vsp.spr-journal.ru/jour/article/view/1921">https://vsp.spr-journal.ru/jour/article/view/1921</self-uri><abstract><p>В лекции анализируются современные сведения об этиологии, ключевых звеньях патогенеза, клинических проявлениях, видах, методах диагностики и лечения опухоли из клеток нотохорды — хордомы. Для оценки уровня усвоения материала лекции приведены ситуационная задача и тестовые вопросы с вариантами правильных ответов.</p></abstract><trans-abstract xml:lang="en"><p>The lecture analyzes modern knowledge about etiology, key mechanisms of pathogenesis, clinical manifestations, types, diagnostic methods and treatment strategy of chordoma (tumor from notochordal cells). To assess the retention of the lecture material, a case problem and multiple-choice test questions are given.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хордома</kwd><kwd>патогенез</kwd><kwd>атипизм клеток</kwd><kwd>белок brachyury</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chordoma</kwd><kwd>pathogenesis</kwd><kwd>atypia of cells</kwd><kwd>protein brachyury</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Не указан</funding-statement><funding-statement xml:lang="en">Not specified</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Genetics home reference [Internet]. Chordoma: National library of medicine’s (US). [cited 2018 Aug 8] Available from: https://ghr. nlm.nih.gov/condition/chordoma#.</mixed-citation><mixed-citation xml:lang="en">Genetics home reference [Internet]. Chordoma: National library of medicine’s (US). 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