vspВопросы современной педиатрииCurrent Pediatrics1682-55271682-5535Издательство «ПедиатрЪ»10.15690/vsp.v18i4.2046vsp-2204Research ArticleОБМЕН ОПЫТОМEXCHANGE OF EXPERIENCEСиндром чувствительной кожи при атопическом дерматите у детей: особенности патогенеза и терапевтической тактикиSensitive Skin Syndrome in Children with Atopic Dermatitis: Pathogenesis and Management Featureshttps://orcid.org/0000-0003-2252-8570МурашкинН. Н.MurashkinNikolay N.

Центральная государственная медицинская академия Управления делами Президента РФ

Мурашкин Николай Николаевич - доктор медицинских наук, профессор, заведующий отделением дерматологии с группой лазерной хирургии НМИЦ здоровья детей.

119991, Москва, Ломоносовский пр-т, д. 2, стр. 1, тел.: +7 (495) 967-14-20

Receiving research grants from pharmaceutical companies Jansen, Eli Lilly, Novartis. Scientific consultant of Galderna, Pierre Fabre, Bayer, Leofarma, Pfizer, AbbVie, Amryt Pharma, Zeldis Pharma LLC companies

m_nn2001@mail.ruhttps://orcid.org/0000-0002-4107-4642ЕпишевР. В.EpishevRoman V.

Москва

Moscow

https://orcid.org/0000-0001-9777-0156ФёдоровД. В.FedorovDmitri V.

Москва

Moscow

https://orcid.org/0000-0002-6034-8231МатерикинА. И.MaterikinAlexander I.

Москва

Moscow

https://orcid.org/0000-0002-8232-8936АмбарчянЭ. Т.AmbarchyanEduard T.

Москва

Moscow

https://orcid.org/0000-0002-0858-8780ОпрятинЛ. А.OpryatinLeonid A.

Москва

Moscow

https://orcid.org/0000-0001-6884-5171СавёловаА. А.SavelovaAlena A.

Москва

Moscow

https://orcid.org/0000-0002-0081-0981ИвановР. А.IvanovRoman A.

Москва

Moscow

https://orcid.org/0000-0002-4022-5592АхмадВ.AhmadWasel

Кабардино-Балкарская Республика

Republic of Kabardino-Balkaria

Национальный медицинский исследовательский центр здоровья детей; Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет); Центральная государственная медицинская академия Управления делами Президента РФРоссияNational Medical Research Center of Children's Health; Sechenov First Moscow State Medical University (Sechenov University); Central State Medical Academy of Department of Presidential AffairsRussian FederationНациональный медицинский исследовательский центр здоровья детейРоссияNational Medical Research Center of Children's HealthRussian FederationКабардино-Балкарский государственный университет им. Х.М. БербековаРоссияBerbekova Kabardino-Balkarian State UniversityRussian Federation201926112019184285293Copyright © Мурашкин Н.Н., Епишев Р.В., Фёдоров Д.В., Материкин А.И., Амбарчян Э.Т., Опрятин Л.А., Савёлова А.А., Иванов Р.А., Ахмад В., 20192019Мурашкин Н.Н., Епишев Р.В., Фёдоров Д.В., Материкин А.И., Амбарчян Э.Т., Опрятин Л.А., Савёлова А.А., Иванов Р.А., Ахмад В.Murashkin N.N., Epishev R.V., Fedorov D.V., Materikin A.I., Ambarchyan E.T., Opryatin L.A., Savelova A.A., Ivanov R.A., Ahmad W.This work is licensed under a Creative Commons Attribution 4.0 License.https://vsp.spr-journal.ru/jour/article/view/2204

Атопический дерматит (АтД) является распространенным кожным заболеванием и оказывает серьезное влияние на качество жизни пациентов и их семей. В последние годы все чаще используется термин «чувствительная кожа», подразумевающий под собой независимый синдром с субъективными ощущениями (жжение, зуд, покалывание и др.), а также утолщением и сухостью кожи в ответ на факторы окружающей среды (биотические, абиотические и антропогенные), которые не вызывают таких симптомов среди здоровых людей. В статье описан патогенез АтД с ассоциированным ему синдромом чувствительной кожи, а также алгоритм их лечения. Проанализированы параметры эффективности и безопасности 1% крема пимекролимус у детей, в том числе при нанесении на участки чувствительной кожи.

The atopic dermatitis (AD) is common skin disease and has significant impact on patients and their families quality of life. In recent years the term “sensitive skin" has been used more frequently. It is separate syndrome with subjective perception (such as burning, itching, tingling, etc.) along with thickening and dryness of the skin in response to environmental factors (biotic, abiotic and anthropogenic) which normally do not cause such symptoms. This syndrome is often associated with AD. The AD and sensitive skin syndrome pathogenesis and their management are presented in the article. Efficiency and safety parameters of pimecrolimus 1% cream in children (including its appliance on sensitive skin areas) are analysed.

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The authors declare that there are no conflicts of interest present.