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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vsp</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы современной педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Current Pediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-5527</issn><issn pub-type="epub">1682-5535</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/vsp.v18i6.2069</article-id><article-id custom-type="elpub" pub-id-type="custom">vsp-2263</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБМЕН ОПЫТОМ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXCHANGE OF EXPERIENCE</subject></subj-group></article-categories><title-group><article-title>Особенности течения и основные подходы к топической терапии пиодермий в детском возрасте</article-title><trans-title-group xml:lang="en"><trans-title>Features and Basic Approaches to Pyoderma Topical Treatment in Children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2252-8570</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мурашкин</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Murashkin</surname><given-names>Nikolay N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мурашкин Николай Николаевич - доктор медицинских наук, профессор, заведующий отделением дерматологии с группой лазерной хирургии НМИЦ здоровья детей; заведующий лабораторией патологии кожи у детей отдела научных исследований в педиатрии НМИЦ здоровья детей; профессор кафедры дерматовенерологии и косметологии ЦГМА; профессор кафедры педиатрии и детской ревматологии Первого МГМУ им.И.М. Сеченова</p><p>119991, Москва, Ломоносовский пр-т, д. 2, стр. 1, тел.: +7 (495) 967-14-20</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">m_nn2001@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0858-8780</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Опрятин</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Opryatin</surname><given-names>Leonid A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4107-4642</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Епишев</surname><given-names>Р. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Epishev</surname><given-names>Roman V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6034-8231</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Материкин</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Materikin</surname><given-names>Alexander I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8232-8936</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Амбарчян</surname><given-names>Э. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Ambarchyan</surname><given-names>Eduard T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0081-0981</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванов</surname><given-names>Р. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanov</surname><given-names>Roman A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный научно-практический центр здоровья детей; Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет); Центральная государственная медицинская академия Управления делами Президента Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center of Children's Health; Sechenov First Moscow State Medical University (Sechenov University); Central State Medical Academy of Department of Presidential Affairs</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Национальный научно-практический центр здоровья детей</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center of Children's Health</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>18</day><month>02</month><year>2020</year></pub-date><volume>18</volume><issue>6</issue><fpage>478</fpage><lpage>484</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мурашкин Н.Н., Опрятин Л.А., Епишев Р.В., Материкин А.И., Амбарчян Э.Т., Иванов Р.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Мурашкин Н.Н., Опрятин Л.А., Епишев Р.В., Материкин А.И., Амбарчян Э.Т., Иванов Р.А.</copyright-holder><copyright-holder xml:lang="en">Murashkin N.N., Opryatin L.A., Epishev R.V., Materikin A.I., Ambarchyan E.T., Ivanov R.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vsp.spr-journal.ru/jour/article/view/2263">https://vsp.spr-journal.ru/jour/article/view/2263</self-uri><abstract><p>Пиодермии — наиболее частая причина обращения детского населения к дерматологам. Устойчивость к развитию пиодермий обусловлена кожным барьером, компонентом которого является кожная микрофлора. Состав микрофлоры кожи человека уникален и зависит от возраста, локализации на различных участках тела, условий окружающей среды. Изменение его качественного и количественного состава предрасполагает к развитию гнойничковых заболеваний кожи, отличающихся клиническим разнообразием, а при неадекватном лечении или его отсутствии — тяжелым течением и развитием осложнений. В этой связи актуальным остается выбор правильной терапии заболевания. В статье проанализированы результаты исследований, в которых изучалась эффективность различных топических антибактериальных средств. Освещены практические аспекты терапии пиодермий у детей с использованием средств для местной терапии.</p></abstract><trans-abstract xml:lang="en"><p>Pyodermas are the most frequent reason for visiting dermatologists among children. The immunity to development of pyodermas is based on skin barrier the part of which is cutaneous microbiome. The microbiome composition is unique and depends on age, localization on various body regions, environment. The change of its qualitative and quantitative composition leads to the development of purulent dermal diseases characterized by clinical diversity and severe course and development of complications (without adequate treatment). In this regard the choice of the correct therapy remains relevant. The results of studies covering the effectiveness of various topic antibacterial agents are analysed. Practical aspects of pyodermia therapy in children using local therapy are illustrated.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>пиодермии</kwd><kwd>кожный барьер</kwd><kwd>микробиом кожи</kwd><kwd>фузидовая кислота</kwd><kwd>фуцидин</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>pyodermas</kwd><kwd>skin barrier</kwd><kwd>cutaneous microbiome</kwd><kwd>fusidic acid</kwd><kwd>fucidin</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Статья опубликована при поддержке компании «Лео Фарма»</funding-statement><funding-statement xml:lang="en">The article has been funded by «LEO Pharma»</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bosko CA. Skin barrier insights: from bricks and mortar to molecules and microbes. 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