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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vsp</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы современной педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Current Pediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-5527</issn><issn pub-type="epub">1682-5535</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/vsp.v13i1.918</article-id><article-id custom-type="elpub" pub-id-type="custom">vsp-233</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБМЕН ОПЫТОМ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXCHANGE OF EXPERIENCE</subject></subj-group></article-categories><title-group><article-title>АНТИБИОТИКОАССОЦИИРОВАННАЯ ДИАРЕЯ В КЛИНИЧЕСКОЙ ПРАКТИКЕ</article-title><trans-title-group xml:lang="en"><trans-title>ANTIBIOTIC-ASSOCIATED DIARRHEA IN CLINICAL PRACTICE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Осадчук</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Osadchuk</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="en"><p>PhD, professor, Head of Polyclinic Department of I.M. Sechenov First Moscow State Medical University</p></bio><email xlink:type="simple">osadchuk.mikhail@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Свистунов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Svistunov</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">osadchuk.mikhail@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет им. И.М. Сеченова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>11</day><month>01</month><year>2014</year></pub-date><volume>13</volume><issue>1</issue><issue-title>Вопросы современной педиатрии</issue-title><fpage>102</fpage><lpage>108</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Осадчук М.А., Свистунов А.А., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Осадчук М.А., Свистунов А.А.</copyright-holder><copyright-holder xml:lang="en">Osadchuk M.A., Svistunov A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vsp.spr-journal.ru/jour/article/view/233">https://vsp.spr-journal.ru/jour/article/view/233</self-uri><abstract><p>В статье систематизированы современные данные по актуальной клинической проблеме — антибиотик-ассоциированной диарее. В возникновении антибиотик-ассоциированной диареи основная роль принадлежит нарушению микробиоценоза и иммунному ответу организма. В терапии этой патологии, наряду с использованием метронидазола и ванкомицина, большое значение придают пробиотикам. Пробиотики играют определенную роль также и в предупреждении рецидива и при профилактике антибиотик-ассоциированной диареи. Комплексный подход к верификации антибиотик-ассоциированной диареи и тактике ведения больных дает возможность значительно уменьшить число и степень тяжести возможных осложнений.</p><p> </p></abstract><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>антибиотик-ассоциированная диарея</kwd><kwd>антибактериальная терапия</kwd><kwd>пробиотики</kwd></kwd-group><kwd-group xml:lang="en"><kwd>antibiotic-associated diarrhea</kwd><kwd>antibiotic treatment</kwd><kwd>probiotics</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bauer M., Kuijper E., van Dissel J. European Society of Clinical Microbiology and Infectious Diseases (ESCMID): treatment guidance document for Clostridium difficile infection (CDI). Clin. Microbiol. Infect. 2009; 15: 1067–1079.</mixed-citation><mixed-citation xml:lang="en">Bauer M., Kuijper E., van Dissel J. 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