vspВопросы современной педиатрииCurrent Pediatrics1682-55271682-5535Издательство «ПедиатрЪ»10.15690/vsp.v19i4.2135vsp-2448Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEWРоль и место смесей на основе частично гидролизованных белков в питании доношенных детей: пищеварительный комфорт и предупреждение аллергииThe Role and Place of Partially Hydrolysed Protein Infant Formulas in the Nutrition of Full-term Children: Digestive Comfort and Allergy Preventionhttps://orcid.org/0000-0003-0941-9871МигачёваН. Б.MigachevaNataliia B.

Мигачёва Наталья Бегиевна, кандидат медицинских наук, доцент кафедры педиатрии Института профессионального образования

443099, Самара, ул. Чапаевская, д. 89

nbmigacheva@gmail.comhttps://orcid.org/0000-0002-1711-1693МухаметоваЕ. М.MukhametovaEvgeniia M.https://orcid.org/0000-0002-1082-8632МакароваЕ. Г.MakarovaEvgeniia G.

Санкт-Петербург;

Москва

Saint-Petersburg;

Moscow

https://orcid.org/0000-0001-6540-9630УкраинцевС. Е.UkraintsevSergey E.Самарский государственный медицинский университетРоссияSamara State Medical UniversityRussian FederationПервый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет)РоссияSechenov First Moscow State Medical University (Sechenov University)Russian FederationСеверо-Западный государственный медицинский университет им. И.И. Мечникова; ООО «НЕСТЛЕ РОССИЯ»РоссияMechnikov North-Western State Medical University; Nestle Russia LLCRussian FederationООО «НЕСТЛЕ РОССИЯ»РоссияNestle Russia LLCRussian Federation202009092020194279290Copyright © Мигачёва Н.Б., Мухаметова Е.М., Макарова Е.Г., Украинцев С.Е., 20202020Мигачёва Н.Б., Мухаметова Е.М., Макарова Е.Г., Украинцев С.Е.Migacheva N.B., Mukhametova E.M., Makarova E.G., Ukraintsev S.E.This work is licensed under a Creative Commons Attribution 4.0 License.https://vsp.spr-journal.ru/jour/article/view/2448

Продолжающийся рост числа случаев развития аллергических болезней и высокая распространенность явлений пищеварительного дискомфорта у детей раннего возраста объясняют интерес педиатров, аллергологов и гастроэнтерологов к разработке и оптимизации диетологических методов профилактики и коррекции данной патологии. В статье обсуждаются современные представления о роли смесей на основе частично гидролизованных белков в питании доношенных детей для коррекции наиболее часто встречающихся функциональных расстройств пищеварения, первичной профилактики аллергии, а также их место в ступенчатой диетотерапии пищевой аллергии. Представлено описание молекулярной характеристики белков коровьего молока и свойств его аллергенов, а также описаны особенности создания и производства смесей на основе частично гидролизованных белков.

The continued increase in the number of allergic diseases and the high prevalence of digestive disturbances in infants explain the interest of pediatricians, allergists and gastroenterologists in the development and improvement of nutritional methods for the prevention and correction of these pathologies. This article discusses current ideas on the role of partially hydrolysed protein formulas in infants’ nutrition for recovery of most common functional gastrointestinal disorders, allergy primary prevention. Also, the article discusses formulas place in sequential nutrition therapy of food allergy. Descriptions of cow milk proteins molecular characteristics and its allergens properties are presented. Features of creation and production of partially hydrolysed protein formulas are described as well.

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The authors declare that there are no conflicts of interest present.