vspВопросы современной педиатрииCurrent Pediatrics1682-55271682-5535Издательство «ПедиатрЪ»10.15690/vsp.v13i1.930vsp-245Research ArticleКРАТКИЕ СООБЩЕНИЯSHORT REPORTSО РОЛИ БАКТЕРИАЛЬНОЙ МИКРОФЛОРЫ В ЭТИОЛОГИИ ХРОНИЧЕСКОГО АДЕНОИДИТА У ДЕТЕЙON THE ROLE OF BACTERIAL MICROFLORA IN ETIOLOGY OF CHRONIC ADENOIDITIS IN CHILDRENТулуповД. А.TulupovD. A.

Tulupov Denis Andreevich, MD, teaching assistant of Department of Pediatric Otolaryngology of of Russian Medical Academy of Post-Graduate Education Address: Barrikadnaja Street, 2/1, Moscow, Russian Federation, 123242, Tel.: (495) 490-89-79, e-mail: tulupovdenis@yandex.ru

tulupovdenis@yandex.ruКарповаЕ. П.KarpovaE. P.tulupovdenis@yandex.ruРоссийская медицинская академия последипломного образования, МоскваРоссияRussian Medical Academy of Post-Graduation Education, MoscowRussian Federation201411012014131Вопросы современной педиатрии172175Copyright © Тулупов Д.А., Карпова Е.П., 20142014Тулупов Д.А., Карпова Е.П.Tulupov D.A., Karpova E.P.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vsp.spr-journal.ru/jour/article/view/245

Представлен обзор результатов клинических исследований по изучению роли патогенной бактериальной флоры в этиологии хронического аденоидита у детей. Согласно литературным данным, основной причиной развития хронической патологии носоглотки у детей является вирусная инфекция. При этом роль бактериальной микрофлоры в развитии хронического аденоидита вторична, но весьма существенна. Основными бактериальными патогенами, выделяемыми из носоглотки детей с хроническим аденоидитом, являются Staphylococcus aureus, Haemophilus influenzae и Streptococcus pneumoniae, однако существует выраженная диссоциация в частоте выделения данных бактериальных патогенов по данным разных исследователей. Значительную роль в формировании персистенции данных патогенов в носоглотке при хроническом аденоидите играет способность бактерий к образованию биопленок. Бактериальные биопленки, а также факт обнаружения большого количества бактерий внутри ткани глоточной миндалины, обусловливают возникновение дискуссии о возможностях системной и топической антибактериальной терапии.

A review of the results of clinical studies on the role of pathogenic bacterial microflora in etiology of chronic adenoiditis in children is shown in this article. According to the literature data the main cause of the development of chronic diseases of the nasopharynx in children is viral infection. The role of the bacterial microflora is secondary, but nevertheless significant. The main bacterial pathogens isolated from the nasopharynx of children with chronic adenoiditis are Staphylococcus aureus, Haemophilus influenzae and Streptococcus pneumonia. However there is significant dissociation in the prevalence of these bacterial agents according to the data of different scientists. Ability of the bacteria to produce biomembranes plays significant role in formation of persistence of the above-mentioned pathogens in the nasopharynx in chronic adenoiditis. Bacterial biomembranes as well as the revealing of the large amounts of bacteria within the tissues of adenoids determines discussions on possibilities of systemic and topical antibacterial treatment.

 

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The authors declare that there are no conflicts of interest present.