vspВопросы современной педиатрииCurrent Pediatrics1682-55271682-5535Издательство «ПедиатрЪ»10.15690/vsp.v19i6.2149vsp-2507Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEWКоморбидности псориаза в детском возрастеPsoriasis Comorbidities in Childhoodhttps://orcid.org/0000-0003-2252-8570МурашкинН. Н.MurashkinNikolay N.

Мурашкин Николай Николаевич, доктор медицинских наук, заведующий отделением дерматологии с группой лазерной хирургии, заведующий лабораторией патологии кожи у детей отдела научных исследований в педиатрии НМИЦ здоровья детей, профессор кафедры дерматовенерологии и косметологии ЦГМА, профессор кафедры педиатрии и детской ревматологии Первого МГМУ им. И.М. Сеченова, заведующий отделом детской дерматологии НИИ педиатрии и охраны здоровья детей ЦКБ РАН

119296, Москва, Ломоносовский пр-т, д. 2, стр. 1

m_nn2001@mail.ruКругловаЛ. С.KruglovaLarisa S.КоваленкоЮ. А.KovalenkoIuliia A.https://orcid.org/0000-0002-8232-8936АмбарчянЭ. Т.AmbarchianEduard T.https://orcid.org/0000-0002-4107-4642ЕпишевР. В.EpishevRoman V.https://orcid.org/0000-0002-6034-8231МатерикинА. И.MaterikinAlexander I.https://orcid.org/0000-0002-0858-8780ОпрятинЛ. А.OpryatinLeonid A.https://orcid.org/0000-0002-0081-0981ИвановР. А.IvanovRoman A.https://orcid.org/0000-0002-8268-069XКуколеваД. С.KukolevaDaria S.https://orcid.org/0000-0001-7771-3314КупцоваД. Г.KuptsovaDaria G.https://orcid.org/0000-0003-0122-5319ПомазановаМ. Ю.PomazanovaMarina Yu.https://orcid.org/0000-0001-9880-0417КозырьЯ. В.KozyrYa. V.Национальный медицинский исследовательский центр здоровья детей; Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет); Центральная государственная медицинская академия Управления делами Президента РФ; НИИ педиатрии и охраны здоровья детей ЦКБ РАНРоссияNational Medical Research Center of Children’s Health; Sechenov First Moscow State Medical University (Sechenov University); Central State Medical Academy of Department of Presidential Affairs; Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”Russian FederationЦентральная государственная медицинская академия Управления делами Президента РФРоссияCentral State Medical Academy of Department of Presidential AffairsRussian FederationНациональный медицинский исследовательский центр здоровья детей; НИИ педиатрии и охраны здоровья детей ЦКБ РАНРоссияNational Medical Research Center of Children’s Health; Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”Russian FederationНациональный медицинский исследовательский центр здоровья детейРоссияNational Medical Research Center of Children’s HealthRussian FederationНациональный медицинский исследовательский центр здоровья детей; Клинический кожно-венерологический диспансерРоссияNational Medical Research Center of Children’s Health; Clinical Dermatovenerologic DispensaryRussian FederationКубанский государственный медицинский университетРоссияKuban State Medical UniversityRussian Federation202025122020196460467Copyright © Мурашкин Н.Н., Круглова Л.С., Коваленко Ю.А., Амбарчян Э.Т., Епишев Р.В., Материкин А.И., Опрятин Л.А., Иванов Р.А., Куколева Д.С., Купцова Д.Г., Помазанова М.Ю., Козырь Я.В., 20202020Мурашкин Н.Н., Круглова Л.С., Коваленко Ю.А., Амбарчян Э.Т., Епишев Р.В., Материкин А.И., Опрятин Л.А., Иванов Р.А., Куколева Д.С., Купцова Д.Г., Помазанова М.Ю., Козырь Я.В.Murashkin N.N., Kruglova L.S., Kovalenko I.A., Ambarchian E.T., Epishev R.V., Materikin A.I., Opryatin L.A., Ivanov R.A., Kukoleva D.S., Kuptsova D.G., Pomazanova M.Y., Kozyr Y.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vsp.spr-journal.ru/jour/article/view/2507

Псориаз — мультифакториальное системное заболевание, характеризующееся избыточным ороговением кожи ввиду нарушения процессов пролиферации и дифференцировки кератиноцитов. Заболевание часто манифестирует в детском возрасте и нередко связано с развитием коморбидных состояний, ряд из которых объединен термином «псориатический марш» (ожирение, метаболический синдром и др.). Течение псориаза и связанных с ним коморбидностей у детей имеет ряд специфических особенностей, обусловливающих актуальность изучения вопросов клинической диагностики и профилактики последних в детском возрасте. В статье резюмированы современные представления о распространенности, особенностях патогенеза и ранней диагностике коморбидных заболеваний у детей с псориазом.

Psoriasis is multifactorial systemic disease characterized by excessive hyperkeratosis due to impaired keratinocytes proliferation and differentiation. This disease often manifests in childhood and it is usually associated with the development of comorbid conditions some of which are combined by the term «psoriatic march» (obesity, metabolic syndrome, etc.). The course of psoriasis and related comorbidities in children has several specific features that determine topicality of studying all the aspects of clinical diagnosis and prevention in childhood. The article summarizes recent ideas on the prevalence, pathogenesis features and early diagnosis of comorbid diseases in children with psoriasis.

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The authors declare that there are no conflicts of interest present.