vspВопросы современной педиатрииCurrent Pediatrics1682-55271682-5535Издательство «ПедиатрЪ»10.15690/vsp.v12i6.889vsp-271Research ArticleКРАТКИЕ СООБЩЕНИЯSHORT REPORTSЛИЗИНОВАЯ СОЛЬ КАРБОЦИСТЕИНА В ТЕРАПИИ ЗАБОЛЕВАНИЙ НИЖНИХ ДЫХАТЕЛЬНЫХ ПУТЕЙ У ДЕТЕЙCARBOCYSTEINE LYSINE SALT MONOHYDRATE IN TREATMENT OF DISEASES OF LOWER RESPIRATORY TRACT IN CHILDRENКрючковаТ. А.KruchkovaT. A.

Kryuchkova Tatyana Alekseevna, Candidate of Medical Science, Assistant Professor of Pediatrics for the course of children’s surgical diseases

haraba.tanya@mail.ruБелгородский государственный национальный исследовательский университетРоссияBelgorod State National Research UniversityRussian Federation201307122013126Вопросы современной педиатрии136139Copyright © Крючкова Т.А., 20132013Крючкова Т.А.Kruchkova T.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vsp.spr-journal.ru/jour/article/view/271

Для воспалительных заболеваний респираторного тракта характерно изменение реологических свойств мокроты и снижение мукоцилиарного клиренса. Подбор мукорегуляторов особенно важен в терапии заболеваний нижних дыхательных путей у детей. Цель исследования: произвести оценку эффективности лизиновой соли карбоцистеина в качестве отхаркивающего средства у детей с заболеваниями органов дыхания. Пациенты и методы: приведены результаты клинического наблюдения за 65 детьми (31 девочка и 34 мальчика) в возрасте от 5 до 16 лет с острыми заболеваниями нижних дыхательных путей, лечившимися в городской детской поликлинике № 4 г. Белгорода. Результаты: показана высокая эффективность и безопасность применения лизиновой соли карбоцистеина в терапии острых и хронических воспалительных заболеваний дыхательных путей у детей — более быстрое выздоровление пациентов, а также возможность сочетания препарата с другими лекарственными средствами, используемыми в педиатрической практике. Выводы: данный препарат при сочетанном применении с антибиотиками усиливает проникновение последних в бронхиальный секрет и слизистую оболочку бронхов, повышая их эффективность. Средство не токсично, хорошо переносится при длительном применении, что позволяет рекомендовать его при лечении кашля у детей как в условиях поликлиники, так и стационара.

Inflammatory diseases of the respiratory tract are characterized by changes in rheological properties of the phlegm and lower of the mucociliary clearance. Adjustment of mucoregulatory agents is of a special significance in treatment of diseases of the lower respiratory tract in children. Aim: to assess efficacy of carbocysteine lysine salt monohydrate as a mucokinetic agent in children with respiratory tract diseases. Patients and methods: 65 children (31 girls and 34 boys) aged from 5 to 16 years old with acute respiratory tract diseases received treatment in Belgorod pediatric out-patient clinic № 4 were included into the study. The results of the clinical follow-up of these children are shown in the article. Results: carbocysteine lysine salt monohydrate was found to be effective and safe in treatment of acute and chronic inflammatory diseases of the respiratory tract in children. The authors observed quicker convalescence of the patients and possibility of combination of this drug with other medicines used in pediatric practice. Conclusions: the above-mentioned drug when used in combination with antibacterial agents intensifies penetration of the latter into the bronchial secretion and bronchial mucous membrane thereby increasing their efficacy. The drug does not have toxicity, is well-tolerated even when prolonged using and can be recommended for treatment of cough in children both under out- and in-patients conditions.

Keywords: children, respiratory tract diseases, carbocysteine.

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The authors declare that there are no conflicts of interest present.