vspВопросы современной педиатрииCurrent Pediatrics1682-55271682-5535Издательство «ПедиатрЪ»10.15690/vsp.v20i5.2310vsp-2755Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEWОбоснование применения крема пимекролимус 1% для проактивной терапии атопического дерматита у детейSubstantiation of Using Pimecrolimus 1% Cream in Proactive Therapy of Children with Atopic Dermatitishttps://orcid.org/0000-0003-2252-8570МурашкинН. Н.MurashkinNikolay N.

Мурашкин Николай Николаевич - доктор медицинских наук, заведующий отделением дерматологии с группой лазерной хирургии Центра детской дерматологии; заведующий лабораторией патологии кожи у детей отдела научных исследований в педиатрии НМИЦ здоровья детей; профессор кафедры дерматовенерологии и косметологии ЦГМА; профессор кафедры педиатрии и детской ревматологии Первого МГМУ им. И.М. Сеченова.119296, Москва, Ломоносовский пр-т, д. 2, стр. 1.Тел.: +7 (495) 967-14-20

Moscow.

m_nn2001@mail.ruhttps://orcid.org/0000-0002-0081-0981ИвановР. А.IvanovRoman A.

Москва. 

Moscow.

https://orcid.org/0000-0002-8232-8936АмбарчянЭ. Т.AmbarchianEduard T.

Москва. 

Moscow.

https://orcid.org/0000-0002-4107-4642ЕпишевР. В.EpishevRoman V.

Москва. 

Moscow.

https://orcid.org/0000-0002-6034-8231МатерикинА. И.MaterikinAlexander I.

Москва. 

Moscow.

https://orcid.org/0000-0002-0858-8780ОпрятинЛ. А.OpryatinLeonid A.

Москва. 

Moscow.

https://orcid.org/0000-0001-6884-5171СавеловаА. А.SavelovaAlena A.

Москва. 

Moscow.

Национальный медицинский исследовательский центр здоровья детей; Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет); Центральная государственная медицинская академияРоссияNational Medical Research Center of Children's Health; Sechenov First Moscow State Medical University (Sechenov University); Central State Medical AcademyRussian FederationНациональный медицинский исследовательский центр здоровья детей; Центральная государственная медицинская академияРоссияNational Medical Research Center of Children's Health; Central State Medical AcademyRussian FederationНИИ педиатрии и охраны здоровья детей ЦКБ РАНРоссияResearch Institute of Pediatrics and Children's Health in “Central Clinical Hospital of the Russian Academy of Sciences”Russian FederationНациональный медицинский исследовательский центр здоровья детейРоссияNational Medical Research Center of Children's HealthRussian Federation202107112021205376382Copyright © Мурашкин Н.Н., Иванов Р.А., Амбарчян Э.Т., Епишев Р.В., Материкин А.И., Опрятин Л.А., Савелова А.А., 20212021Мурашкин Н.Н., Иванов Р.А., Амбарчян Э.Т., Епишев Р.В., Материкин А.И., Опрятин Л.А., Савелова А.А.Murashkin N.N., Ivanov R.A., Ambarchian E.T., Epishev R.V., Materikin A.I., Opryatin L.A., Savelova A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vsp.spr-journal.ru/jour/article/view/2755

Атопический дерматит (АтД) является многофакторным воспалительным заболеванием кожи с высокой распространенностью в детской популяции. Согласно актуальным клиническим руководствам и экспертным докладам, для предупреждения обострений АтД необходимо проведение длительного поддерживающего лечения. В статье обобщены результаты основных исследований крема пимекролимус 1%. Показаны его эффективность и благоприятный профиль безопасности при длительной проактивной терапии АтД у детей.

Atopic dermatitis (AtD) is multifactorial inflammatory skin disease with high prevalence in pediatric population. It is crucial to implement long-term maintenance therapy to prevent AtD exacerbations according to current clinical guidelines and expert reports. The article summarizes the results of the major studies on using pimecrolimus 1% cream. Its efficacy and safety in long-term proactive therapy of children with AtD are presented.

атопический дерматитпимекролимуспроактивная терапияподдерживающая терапиялимфомаатрофиятопические ингибиторы кальциневринадетиatopic dermatitispimecrolimusproactive therapymaintenance therapylymphomaatrophytopical calcineurin inhibitorchildrenСтатья подготовлена при финансовой поддержке компании Viatris.The article has been funded by Viatris.ReferencesMaliyar K, Sibbald C, Pope E, et al. Diagnosis and Management of Atopic Dermatitis. Adv Skin Wound Care. 2018;31(12):538-550. doi: 10.1097/01.asw.0000547414.38888.8dMaliyar K, Sibbald C, Pope E, et al. Diagnosis and Management of Atopic Dermatitis. Adv Skin Wound Care. 2018;31(12):538-550. doi: 10.1097/01.asw.0000547414.38888.8dAsher MI, Montefort S, Bjorksten B, et al. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. 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The authors declare that there are no conflicts of interest present.