vspВопросы современной педиатрииCurrent Pediatrics1682-55271682-5535Издательство «ПедиатрЪ»10.15690/vsp.v21i4.2435vsp-3009Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEWРаспространенность недостаточности/дефицита витамина D и их влияние на риск развития и течение атопического дерматита у детейPrevalence of Vitamin D Insufficiency/Deficiency and Their Role in Atopic Dermatitis Development and Course in Childrenhttps://orcid.org/0000-0001-8184-9230КашинскаяТ. С.KashinskayaTatiana S.

Кашинская Татьяна Сергеевна, ассистент кафедры пропедевтики детских болезней

656038, Барнаул, пр. Ленина, д. 40

Barnaul

kashinskaya_agmu@mail.ruhttps://orcid.org/0000-0002-7143-8259ШаховаН. В.ShakhovaNatalia V.

Барнаул

Barnaul

https://orcid.org/0000-0001-7801-0223ЛобановЮ. Ф.LobanovYrij F.

Барнаул

Barnaul

https://orcid.org/0000-0002-2234-5355КамалтыноваЕ. М.KamaltynovaElena M.

Томск

Tomsk

Алтайский государственный медицинский университетРоссияAltai State Medical UniversityRussian FederationСибирский государственный медицинский университетРоссияSiberian State Medical UniversityRussian Federation202204102022214305310Copyright © Кашинская Т.С., Шахова Н.В., Лобанов Ю.Ф., Камалтынова Е.М., 20222022Кашинская Т.С., Шахова Н.В., Лобанов Ю.Ф., Камалтынова Е.М.Kashinskaya T.S., Shakhova N.V., Lobanov Y.F., Kamaltynova E.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vsp.spr-journal.ru/jour/article/view/3009

В последние десятилетия получены убедительные данные об участии витамина D в патогенезе атопического дерматита (АтД). В большом количестве исследований у пациентов с АтД обнаружена низкая концентрация 25(ОН)D в крови, которая, по некоторым данным, ассоциирована с высокой концентрацией аллерген-специфических IgE. Представлен анализ распространенности низкой концентрации 25(ОН)D, ассоциации недостаточности витамина D с тяжестью АтД и сенсибилизацией к аллергенам, а также связи нарушений приема витамина D с риском развития АтД.

Various conclusive evidence on the role of vitamin D in the pathogenesis of atopic dermatitis (AD) has been obtained in recent decades. Many studies have shown that patients with AD have low concentration of 25(OH)D in blood associated with high concentration of allergen specific IgE (according to several reports). The analysis of low 25(OH)D concentration prevalence, association of vitamin D deficiency with AD severity and sensitization to allergens, and association of vitamin D disorders with risk of AD development is presented.

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The authors declare that there are no conflicts of interest present.