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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vsp</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы современной педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Current Pediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-5527</issn><issn pub-type="epub">1682-5535</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/vsp.v12i4.746</article-id><article-id custom-type="elpub" pub-id-type="custom">vsp-320</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В ПОМОЩЬ  ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>A DOCTOR’S AID</subject></subj-group></article-categories><title-group><article-title>ПРИМЕНЕНИЕ НОВОЙ ФОРМЫ ИБУПРОФЕНА У ДЕТЕЙ С ЛИХОРАДКОЙ ПРИ ОСТРЫХ РЕСПИРАТОРНЫХ ИНФЕКЦИЯХ</article-title><trans-title-group xml:lang="en"><trans-title>USE OF A NEW FORM OF IBUPROFEN IN CHILDREN WITH FEVER AND ACUTE RESPIRATORY TRACT INFECTIONS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Локшина</surname><given-names>Э. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Lokshina</surname><given-names>E. E.</given-names></name></name-alternatives><email xlink:type="simple">neonatepearl@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайцева</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaitseva</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">neonatepearl@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайцева</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaitseva</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="en"><p>Zaitseva Ol’ga Vital’evna, Phd, professor, Head of the Department of Pediatrics</p></bio><email xlink:type="simple">neonatepearl@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Клендар</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Klendar</surname><given-names>G. A.</given-names></name></name-alternatives><email xlink:type="simple">neonatepearl@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Степанова</surname><given-names>И. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Stepanova</surname><given-names>I. G.</given-names></name></name-alternatives><email xlink:type="simple">neonatepearl@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мисуренко</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Misurenko</surname><given-names>O. N.</given-names></name></name-alternatives><email xlink:type="simple">neonatepearl@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Селиванова</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Selivanova</surname><given-names>I. N.</given-names></name></name-alternatives><email xlink:type="simple">neonatepearl@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шамонина</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shamonina</surname><given-names>N. V.</given-names></name></name-alternatives><email xlink:type="simple">neonatepearl@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Касаткина</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kasatkina</surname><given-names>M. S.</given-names></name></name-alternatives><email xlink:type="simple">neonatepearl@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Равшанова</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Ravshanova</surname><given-names>L. S.</given-names></name></name-alternatives><email xlink:type="simple">neonatepearl@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский государственный медико-стоматологический университет им. А.И. Евдокимова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.I. Evdokimov Moscow State Medico-Stomatological University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Центральная детская клиническая больница ФМБА России, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central Pediatric Clinical Hospital of FMBA of Russia, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Детская городская клиническая больница Святого Владимира, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>St. Vladimir Pediatric Municipal Clinical Hospital, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>12</day><month>07</month><year>2013</year></pub-date><volume>12</volume><issue>4</issue><issue-title>Вопросы современной педиатрии</issue-title><fpage>166</fpage><lpage>171</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Локшина Э.Э., Зайцева С.В., Зайцева О.В., Клендар Г.А., Степанова И.Г., Мисуренко О.Н., Селиванова И.Н., Шамонина Н.В., Касаткина М.С., Равшанова Л.С., 2013</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Локшина Э.Э., Зайцева С.В., Зайцева О.В., Клендар Г.А., Степанова И.Г., Мисуренко О.Н., Селиванова И.Н., Шамонина Н.В., Касаткина М.С., Равшанова Л.С.</copyright-holder><copyright-holder xml:lang="en">Lokshina E.E., Zaitseva S.V., Zaitseva O.V., Klendar G.A., Stepanova I.G., Misurenko O.N., Selivanova I.N., Shamonina N.V., Kasatkina M.S., Ravshanova L.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vsp.spr-journal.ru/jour/article/view/320">https://vsp.spr-journal.ru/jour/article/view/320</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>острые респираторные инфекции</kwd><kwd>лихорадка</kwd><kwd>боль</kwd><kwd>ибупрофен</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>acute respiratory tract infections</kwd><kwd>fever</kwd><kwd>pain</kwd><kwd>ibuprofen</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Korovina N. A., Zaplatnikov A. L., Zakharova I. N. Likhoradka u detei. Ratsional'nyi vybor zharoponizhayushchikh lekarstvennykh sredstv [Fever in Children. Sensible Choice of Antifebrile Medicine]. Moscow, 2000. 67 p.</mixed-citation><mixed-citation xml:lang="en">Korovina N. A., Zaplatnikov A. L., Zakharova I. N. Likhoradka u detei. Ratsional'nyi vybor zharoponizhayushchikh lekarstvennykh sredstv [Fever in Children. Sensible Choice of Antifebrile Medicine]. Moscow, 2000. 67 p.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Zaitseva O. V. Consilium Medicum — Consilium Medicum. 2007; 1: 21–23.</mixed-citation><mixed-citation xml:lang="en">Zaitseva O. V. Consilium Medicum — Consilium Medicum. 2007; 1: 21–23.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Vetrov V. P., Dlin V. V., Osmanov I. M., Makar'yants M. L., Fisenko V. P. Ratsional'noe primenenie antipiretikov u detei. Pos. dlya vrachei [Sensible Application of Antiseptic Medicine for Children]. Moscow, 2002. 23 p.</mixed-citation><mixed-citation xml:lang="en">Vetrov V. P., Dlin V. V., Osmanov I. M., Makar'yants M. L., Fisenko V. P. Ratsional'noe primenenie antipiretikov u detei. Pos. dlya vrachei [Sensible Application of Antiseptic Medicine for Children]. Moscow, 2002. 23 p.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">van den Anker J. N. Optimising the management of fever and pain in children. Int. J. Clin. Pract. Suppl. 2013; 178: 26–32.</mixed-citation><mixed-citation xml:lang="en">van den Anker J. N. Optimising the management of fever and pain in children. Int. J. Clin. Pract. Suppl. 2013; 178: 26–32.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Chiappini E., Venturini E., Principi N., Longhi R., Tovo P. A., Becherucci P., Bonsignori F., Esposito S., Festini F., Galli L., Lucchesi B., Mugelli A., de Martino M. Update of the 2009 Italian Pediatric Society Guidelines about management of fever in children. Clin. Ther. 2012; 34 (7): 1648–1653.</mixed-citation><mixed-citation xml:lang="en">Chiappini E., Venturini E., Principi N., Longhi R., Tovo P. A., Becherucci P., Bonsignori F., Esposito S., Festini F., Galli L., Lucchesi B., Mugelli A., de Martino M. Update of the 2009 Italian Pediatric Society Guidelines about management of fever in children. Clin. Ther. 2012; 34 (7): 1648–1653.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Pereira G. L., Dagostini J. M., Pizzol Tda S. Alternating antipyretics in the treatment of fever in children: a systematic review of randomized clinical trials. J. Pediatr. (Rio J.). 2012; 88 (4): 289–296.</mixed-citation><mixed-citation xml:lang="en">Pereira G. L., Dagostini J. M., Pizzol Tda S. Alternating antipyretics in the treatment of fever in children: a systematic review of randomized clinical trials. J. Pediatr. (Rio J.). 2012; 88 (4): 289–296.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Purssell E. Systematic review of studies comparing combined treatment with paracetamol and ibuprofen, with either drug alone. Arch. Dis. Child. 2011; 96 (12): 1175–1179.</mixed-citation><mixed-citation xml:lang="en">Purssell E. Systematic review of studies comparing combined treatment with paracetamol and ibuprofen, with either drug alone. Arch. Dis. Child. 2011; 96 (12): 1175–1179.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization (WHO). WHO model list of essential medicines for children [updated 2011 Mar]. URL: http://www.who.int/ medicines/publications/essentialmedicines/en</mixed-citation><mixed-citation xml:lang="en">World Health Organization (WHO). WHO model list of essential medicines for children [updated 2011 Mar]. URL: http://www.who.int/ medicines/publications/essentialmedicines/en</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Baranov A. A., Tatochenko V. K., Bakradze M. D. Likhoradochnye sindromy u detei: rekomendatsii po diagnostike i lecheniyu [Feverish Syndromes in Children: Guideline on Diagnosis and treatment]. Moscow, Soyuz pediatrov Rossii, 2011. 228 p.</mixed-citation><mixed-citation xml:lang="en">Baranov A. A., Tatochenko V. K., Bakradze M. D. Likhoradochnye sindromy u detei: rekomendatsii po diagnostike i lecheniyu [Feverish Syndromes in Children: Guideline on Diagnosis and treatment]. Moscow, Soyuz pediatrov Rossii, 2011. 228 p.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Li S. F., Lacher B., Grain E. F. Acetaminophen and ibuprofen dosing by parents. Pediatr. Emerg. Care. 2000; 16: 394–397.</mixed-citation><mixed-citation xml:lang="en">Li S. F., Lacher B., Grain E. F. Acetaminophen and ibuprofen dosing by parents. Pediatr. Emerg. Care. 2000; 16: 394–397.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Goldman R. D., Ko K., Linett L. J., Solknik D. Antipyretic efficacy and safety of ibuprofen and acetaminophen in children. Ann. Pharmacother. 2004; 38: 146–150. 12. Perrott D. A., Piira T., Goodenough B., Champion D. Efficacy and safety of acetaminophen vs. ibuprofen for treating children's pain or fever: a meta-analysis. Arch. Pediatr. Adolesc. Med. 2004; 158: 521–526.</mixed-citation><mixed-citation xml:lang="en">Goldman R. D., Ko K., Linett L. J., Solknik D. Antipyretic efficacy and safety of ibuprofen and acetaminophen in children. Ann. Pharmacother. 2004; 38: 146–150. 12. Perrott D. A., Piira T., Goodenough B., Champion D. Efficacy and safety of acetaminophen vs. ibuprofen for treating children's pain or fever: a meta-analysis. Arch. Pediatr. Adolesc. Med. 2004; 158: 521–526.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Hay A. D., Costelloe C., Redmond N. M., Montgomery A. A., Fletcher M., Hollinghurst S., Peters T. J. Paracetamol plus ibuprofen for the treatment of fever in children (PITCH): randomised controlled trial. BMJ. 2008; 337: 1302.</mixed-citation><mixed-citation xml:lang="en">Hay A. D., Costelloe C., Redmond N. M., Montgomery A. A., Fletcher M., Hollinghurst S., Peters T. J. Paracetamol plus ibuprofen for the treatment of fever in children (PITCH): randomised controlled trial. BMJ. 2008; 337: 1302.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Lesko S. M., Mitchell A. A. The safety of acetaminophen and ibuprofen among children younger than 2 years old. Pediatrics. 1999; 104: 39.</mixed-citation><mixed-citation xml:lang="en">Lesko S. M., Mitchell A. A. The safety of acetaminophen and ibuprofen among children younger than 2 years old. Pediatrics. 1999; 104: 39.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Chandrasekharan N. V., Dai H., Roos K. L., Evanson N. K., Tomsik J., Elton T. S., Simmons D. L. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression. Proc. Natl. Acad. Sci. USA. 2002; 99 (21): 13926–13931.</mixed-citation><mixed-citation xml:lang="en">Chandrasekharan N. V., Dai H., Roos K. L., Evanson N. K., Tomsik J., Elton T. S., Simmons D. L. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression. Proc. Natl. Acad. Sci. USA. 2002; 99 (21): 13926–13931.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Zaitseva O. V. Pediatriya — Pediatrics. 2004; 2: 37–41.</mixed-citation><mixed-citation xml:lang="en">Zaitseva O. V. Pediatriya — Pediatrics. 2004; 2: 37–41.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Porter J. D., Robinson P. H., Glasgow J. F., Banks J. H., Hall S. M. Trends in the incidence of Reye's syndrome and the use of aspirin. Arch. Dis. Child. 1990; 65: 826–829.</mixed-citation><mixed-citation xml:lang="en">Porter J. D., Robinson P. H., Glasgow J. F., Banks J. H., Hall S. M. Trends in the incidence of Reye's syndrome and the use of aspirin. Arch. Dis. Child. 1990; 65: 826–829.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Merlani G., Fox M., Oehen H. P., Cathomas G., Renner E. L., Fattinger K., Schneemann M., Kullak-Ublick G. A. Fatal hepatotoxicity secondary to nimesulide. Eur. J. Clin. Pharmacol. 2001; 57: 321–326.</mixed-citation><mixed-citation xml:lang="en">Merlani G., Fox M., Oehen H. P., Cathomas G., Renner E. L., Fattinger K., Schneemann M., Kullak-Ublick G. A. Fatal hepatotoxicity secondary to nimesulide. Eur. J. Clin. Pharmacol. 2001; 57: 321–326.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
