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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vsp</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы современной педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Current Pediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-5527</issn><issn pub-type="epub">1682-5535</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/vsp.v12i3.682</article-id><article-id custom-type="elpub" pub-id-type="custom">vsp-331</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В ПОМОЩЬ  ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>A DOCTOR’S AID</subject></subj-group></article-categories><title-group><article-title>ПРИМЕНЕНИЕ ПРИРОДНОЙ МИНЕРАЛЬНОЙ ВОДЫ, ОБОГАЩЕННОЙ МАГНИЕМ, ПРИ ЛЕЧЕНИИ ЗАПОРОВ У ДЕТЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>NATURAL MINERAL WATER ENRICHED WITH MAGNESIUM IN CHILDREN WITH CONSTIPATIONS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захарова</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharova</surname><given-names>I. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Zaharova Irina Nikolaevna, PhD, professor, Head of the Pediatrics Department of theFaculty of Pediatrics of Russian Medical Academy of Post-Graduate Education, Chief Pediatrician of the Central Federal Region of Russian Federation, Honoured Doctor of Russian Federation</p><p>Address: Barrikadnaja Street, 2/1, Moscow, Russian Federation, 123480, Tel.: (495) 495-52-38, e-mail: zakharova-rmapo@yandex.ru</p></bio><email xlink:type="simple">zakharova-rmapo@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Елезова</surname><given-names>Л. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Elezova</surname><given-names>L. I.</given-names></name></name-alternatives><email xlink:type="simple">zakharova-rmapo@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Степурина</surname><given-names>Л. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Stepunina</surname><given-names>L. L.</given-names></name></name-alternatives><email xlink:type="simple">zakharova-rmapo@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Катаева</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kataeva</surname><given-names>L. A.</given-names></name></name-alternatives><email xlink:type="simple">zakharova-rmapo@yandex.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шмаков</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shmakov</surname><given-names>N. A.</given-names></name></name-alternatives><email xlink:type="simple">zakharova-rmapo@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лагадзе</surname><given-names>И. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Lagadze</surname><given-names>I. B.</given-names></name></name-alternatives><email xlink:type="simple">zakharova-rmapo@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российская медицинская академия последипломного образования, Москва,</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Post-graduate Education, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Центральный клинический санаторий «Малаховка» ФМБА России, Московская область</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central Clinical Sanatorium «Malakhovka» of the Federal Medical and Biological Agency of Russian, Moscow region</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Российская медицинская академия последипломного образования, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Post-graduate Education, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Тушинская детская городская больница, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tushino Children Municipal Hospital, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>14</day><month>05</month><year>2013</year></pub-date><volume>12</volume><issue>3</issue><issue-title>Вопросы современной педиатрии</issue-title><fpage>56</fpage><lpage>63</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Захарова И.Н., Елезова Л.И., Степурина Л.Л., Катаева Л.А., Шмаков Н.А., Лагадзе И.Б., 2013</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Захарова И.Н., Елезова Л.И., Степурина Л.Л., Катаева Л.А., Шмаков Н.А., Лагадзе И.Б.</copyright-holder><copyright-holder xml:lang="en">Zakharova I.N., Elezova L.I., Stepunina L.L., Kataeva L.A., Shmakov N.A., Lagadze I.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vsp.spr-journal.ru/jour/article/view/331">https://vsp.spr-journal.ru/jour/article/view/331</self-uri><abstract><p>В статье приведена характеристика лечебных минеральных вод, обсуждается роль магния для функционирования организма человека, нормальной работы пищеварительного тракта. Цель исследования: изучить влияние минеральной воды, обогащенной магнием, на характер стула у детей, страдающих запорами, установить необходимую дозу, переносимость, а также исследовать влияние комбинации минеральной и артезианской питьевой воды на функциональное состояние кишечника у детей с хроническими запорами. Пациенты и методы исследования: в первом исследовании приняли участие 60 детей с хроническими запорами (30 человек в исследуемой группе и 30 — в контрольной). Минеральную воду детям исследуемой группы назначали в разовой дозе 3–5 мл на 1 кг массы на прием, 3 раза/сут, курс лечения продолжался в течение 10 сут в условиях стационара, затем — амбулаторно, еще в течение 3 нед. Во втором исследовании под наблюдением находились 45 детей в возрасте 3–15 лет, страдающих хроническими запорами, находившихся на санаторно-курортном лечении. Пациенты были распределены на 2 группы: в основную вошли 25 детей, которые на фоне проводимой терапии получали одновременно лечебную минеральную и артезианскую питьевую воду. Минеральная вода назначалась в разовой дозе 3–5 мл на 1 кг массы на прием 3 раза/сут до еды. Артезианскую питьевую воду давали из расчета 6 мл на 1 кг массы после еды. Продолжительность курса сочетанного лечения минеральными водами составила 21 сут. В группу сравнения были включены 20 детей, получавших минеральную воду средней минерализации. Во время первого исследования проводили клинический осмотр детей, оценивали кратность стула, изучали клинический анализ крови. Во время обоих исследований оценивали клинический эффект минеральной воды в виде получения регулярного оформленного стула. Результаты: данные, полученные в первом исследовании, позволяют рекомендовать минеральную воду детям, страдающим хроническими запорами в качестве слабительного средства в дозе 3–5 мл на 1 кг массы тела на прием. Ее следует принимать за 15–20 мин до еды в полной разовой дозе 3 раза/сут. Курс лечения хронических запоров функционального генеза у детей должен составлять не менее 4 нед. По результатам второго исследования, сочетанный прием минеральной и артезианской воды приводил к нормализации не только частоты и консистенции стула, но и к купированию диспепсических явлений и абдоминального синдрома, которые часто сопровождают функциональные запоры у детей, а также к восстановлению аппетита. Выводы: включение в схему лечения хронических запоров минеральной воды, а также ее комбинации с артезианской водой существенно повышает эффективность терапии.</p></abstract><trans-abstract xml:lang="en"><p>Characteristics of medicinal mineral waters as well as the role of magnesium in human organism activity and normal functioning of the gastrointestinal tract are discussed in this article. Aim: to study the influence of mineral water enriched with magnesium on stool of children suffering from constipations, to determine the appropriate dosage and tolerance to such water and to research the effect of the combination of mineral and artesian drinking water on the functioning of the intestines of children with constipations. Patients and methods: 60 patients with chronic constipations (30 — in the study group and 30 — in control group) were included into the first study. Children from the study group were administered mineral water at the dosage of 3–5 ml/kg of the body weight 3 times per day, the treatment course was 10 days at hospital and after that — for 3 weeks in outpatient conditions. The second study included 45 children at the age of 3–15 years old, suffered from chronic constipations, who received sanatorium-and-spa treatment. Patients were divided into 2 groups: 25 were included into the main group, they were administered simultaneously medicinal mineral and artesian water. Mineral water was given at the dosage of 3–5 ml/kg of the body weight 3 times per day before eating. Artesian drinking water was given at the dosage of 6 ml/kg of body weight after eating. The duration of combination treatment was 21 days. Comparison group consisted of 20 children, receiving moderate mineral water. During the first study clinical examination of children was performed, the number of defecation was assessed and the blood samples were performed. During the second study clinical effect of mineral water in the form of regular formed stool was assessed. Results: data from the first study allow to recommend mineral water in treatment of children with chronic constipations as laxative agent at the dosage of 3–5 ml/kg of the body weight.  It should be received 15–20 minutes before eating at the full dosage 3 times per day. The course of treatment of chronic functional constipations in children must be at least 4 weeks. According to the results of the second study, combination administration of mineral and artesian water led both to normalization of the stool frequency and consistence and arresting of dyspeptic symptoms and abdominal syndrome, which often accompanied functional chronic constipations, as well as appetite improvement. Conclusions: including of mineral water into the scheme of treatment of chronic constipations and its combination with artesian water significantly increase the efficacy of therapy.</p><p>Key words: children, mineral water, artesian water, gastrointestinal tract, chronic constipation, magnesium, mineralization, spa Rogashka Slatina, efficacy of treatment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>минеральная вода</kwd><kwd>артезианская вода</kwd><kwd>желудочно-кишечный тракт</kwd><kwd>хронический запор</kwd><kwd>магний</kwd><kwd>минерализация</kwd><kwd>курорт Рогашка Слатина</kwd><kwd>эффективность лечения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>mineral water</kwd><kwd>artesian water</kwd><kwd>gastrointestinal tract</kwd><kwd>chronic constipation</kwd><kwd>magnesium</kwd><kwd>mineralization</kwd><kwd>spa Rogashka Slatina</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Korovina N. 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