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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vsp</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы современной педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Current Pediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-5527</issn><issn pub-type="epub">1682-5535</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/vsp.v12i2.625</article-id><article-id custom-type="elpub" pub-id-type="custom">vsp-351</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБМЕН ОПЫТОМ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXCHANGE OF EXPERIENCE</subject></subj-group></article-categories><title-group><article-title>Эффективность и безопасность антиоксидантов в комплексной терапии инфекционных болезней у часто болеющих детей</article-title><trans-title-group xml:lang="en"><trans-title>Efficacy and Safety of Antioxidants in Complex Therapy of Infectious Diseases in Frequently Ill Children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бабаян</surname><given-names>М. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Babayan</surname><given-names>M. L.</given-names></name></name-alternatives><bio xml:lang="en"><p>Contacts: Babayan Margarita Levonovna, PhD, MD, pediatrician, gastroenterologist, Federal State Budget Institution “Moscow Scientific Research Institute of Pediatrics and Children’s Surgery”, Ministry of Health, Russian Federation Address: 125412, Moscow, Taldomskaya, 2, Tel.: (499) 487-46-81, e-mail: margarita.babayan@gmail.com</p></bio><email xlink:type="simple">margarita.babayan@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский НИИ педиатрии и детской хирургии,</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Scientific Research Institute of Pediatrics and Pediatric Surgery</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>19</day><month>03</month><year>2013</year></pub-date><volume>12</volume><issue>2</issue><issue-title>Вопросы современной педиатрии</issue-title><fpage>85</fpage><lpage>88</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бабаян М.Л., 2013</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Бабаян М.Л.</copyright-holder><copyright-holder xml:lang="en">Babayan M.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vsp.spr-journal.ru/jour/article/view/351">https://vsp.spr-journal.ru/jour/article/view/351</self-uri><abstract><p>Острые респираторные инфекции — наиболее часто встречающиеся заболевания детей дошкольного и школьного возраста. Диспансерная группа часто болеющих детей требует дополнительных реабилитационных мероприятий после перенесенных заболеваний. В статье приведен обзор российских исследований клинической эффективности антиоксидантного поливитаминного препарата среди часто и длительно болеющих детей. В состав препарата входят β-каротин, аскорбиновая кислота и витамин Е. Полученные данные убедительно показывают, что применение данного поливитамина в качестве неспецифического средства в профилактике и комплексной терапии острых респираторных инфекций является безопасным и эффективным.</p></abstract><trans-abstract xml:lang="en"><p>Acute respiratory infections are the most common diseases among pre-school and school children. Special group of frequently ill children demands additional rehabilitation measures after endured diseases. The author provides a review of Russian investigations on clinical efficacy of anti-oxidative polyvitamin drug among frequently and protractedly ill children. β-carotene, ascorbic acid and vitamin E are included into the composition of this drug. The received data strongly suggest that usage of this polyvitamin as a non-specific medicine to prevention and complex therapy of acute respiratory infections is safe and efficient.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>часто болеющие дети</kwd><kwd>β-каротин</kwd><kwd>эффективность</kwd><kwd>безопасность</kwd><kwd>острые респираторные инфекции</kwd></kwd-group><kwd-group xml:lang="en"><kwd>frequently ill children</kwd><kwd>β-carotene</kwd><kwd>efficacy</kwd><kwd>safety</kwd><kwd>acute respiratory infection</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Zaytseva O. V., Zaytseva S. V. Treatment and prophylaxis of acute respiratory infections in frequently ailing children. Doctor in charge. 2008; 8: 53–57.</mixed-citation><mixed-citation xml:lang="en">Zaytseva O. V., Zaytseva S. V. Treatment and prophylaxis of acute respiratory infections in frequently ailing children. Doctor in charge. 2008; 8: 53–57.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Zaplatnikov A. L., Ivanov V. A., Sharapov N. V. Health state of fre qu en tly ailing children and increase of effectiveness of their sanatorium health improvement. Russian medical journal. 2007; 15 (21): 1559–1565.</mixed-citation><mixed-citation xml:lang="en">Zaplatnikov A. L., Ivanov V. A., Sharapov N. V. Health state of fre qu en tly ailing children and increase of effectiveness of their sanatorium health improvement. Russian medical journal. 2007; 15 (21): 1559–1565.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Modern approaches to the treatment and rehabilitation of frequently ailing children: a manual for doctors. Edited by L. S. Baleva, N. A. Korovina, V. K. Tatochenko. Moscow: Agency of Medical Marketing. 2006. 56 pp.</mixed-citation><mixed-citation xml:lang="en">Modern approaches to the treatment and rehabilitation of frequently ailing children: a manual for doctors. Edited by L. S. Baleva, N. A. Korovina, V. K. Tatochenko. Moscow: Agency of Medical Marketing. 2006. 56 pp.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Albitskiy V.Yu., Baranov A. A. Frequently ailing children. Clinicalsocial aspects. The ways of health improvement. Saratov. 1986.</mixed-citation><mixed-citation xml:lang="en">Albitskiy V.Yu., Baranov A. A. Frequently ailing children. Clinicalsocial aspects. The ways of health improvement. Saratov. 1986.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Yartsev M. N., Yakovlev K. P. Primary immunodeficiency states. Quality of life. Moscow: Medicine. 2005; 4: 66–72.</mixed-citation><mixed-citation xml:lang="en">Yartsev M. N., Yakovlev K. P. Primary immunodeficiency states. Quality of life. Moscow: Medicine. 2005; 4: 66–72.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Verkovich N. V. Immunal and Vetoron in complex therapy of children 0–3 years old with atopic dermatitis. Author’s abstract of a doctoral thesis. Moscow. 2000. 22 pp.</mixed-citation><mixed-citation xml:lang="en">Verkovich N. V. Immunal and Vetoron in complex therapy of children 0–3 years old with atopic dermatitis. Author’s abstract of a doctoral thesis. Moscow. 2000. 22 pp.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Martynova G. P., Bogvilene Ya. A., Vaytsel Ye. V., Yevreimova S. V., Saybel I. V. Treatment with в-carotene in complex therapy of chickenpox in children. Consilium mеdicum. 2011; 2; 28–31.</mixed-citation><mixed-citation xml:lang="en">Martynova G. P., Bogvilene Ya. A., Vaytsel Ye. V., Yevreimova S. V., Saybel I. V. Treatment with в-carotene in complex therapy of chickenpox in children. Consilium mеdicum. 2011; 2; 28–31.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Tutelyan A. V., Spirichev V. B., Sukhanov B. P., Kudasheva V. A. Micronutrients in nutrition of healthy and ill human. Moscow: Kolos. 2002.</mixed-citation><mixed-citation xml:lang="en">Tutelyan A. V., Spirichev V. B., Sukhanov B. P., Kudasheva V. A. Micronutrients in nutrition of healthy and ill human. Moscow: Kolos. 2002.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Khabarov A. S., Zyablitskaya N. K. Efficacy of Vetoron for children in complex therapy of chickenpox. Practice of a pediatrician. 2011. Pp. 39–42.</mixed-citation><mixed-citation xml:lang="en">Khabarov A. S., Zyablitskaya N. K. Efficacy of Vetoron for children in complex therapy of chickenpox. Practice of a pediatrician. 2011. Pp. 39–42.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Buring J. Е., Gaziano J. М. Antioxidant vitamins and cardiovas cular disease preventive nutrition. A. Bendich, R. J. Deckelbaum (eds.). N.-Y.: Totowa, Human Press. 1997. P. 171–180.</mixed-citation><mixed-citation xml:lang="en">Buring J. Е., Gaziano J. М. Antioxidant vitamins and cardiovas cular disease preventive nutrition. A. Bendich, R. J. Deckelbaum (eds.). N.-Y.: Totowa, Human Press. 1997. P. 171–180.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Jason J., Archibald L. K., Nwanyanwu O. C., Sowell A. L., Buchanan I., Larned J., Bell M., Kazembe P. N., Dobbie H., Jarvis W. R. Vitamin A levels and immunity in humans. Clin. Diagnost. Lab. Immunol. 2002; 9 (3): 616–621.</mixed-citation><mixed-citation xml:lang="en">Jason J., Archibald L. K., Nwanyanwu O. C., Sowell A. L., Buchanan I., Larned J., Bell M., Kazembe P. N., Dobbie H., Jarvis W. R. Vitamin A levels and immunity in humans. Clin. Diagnost. Lab. Immunol. 2002; 9 (3): 616–621.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Kazyulin A. N. Principles of administration of vitamins and vitamin-mineral complex in prophylactic and clinical medicine. Handbook of polyclinic doctor. 2008; 2: 19–24.</mixed-citation><mixed-citation xml:lang="en">Kazyulin A. N. Principles of administration of vitamins and vitamin-mineral complex in prophylactic and clinical medicine. Handbook of polyclinic doctor. 2008; 2: 19–24.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Prophorovich Ye. A. How should vitamin-mineral complex be chosen? Handbook of polyclinic doctor. 2009; 1: 3–8.</mixed-citation><mixed-citation xml:lang="en">Prophorovich Ye. A. How should vitamin-mineral complex be chosen? Handbook of polyclinic doctor. 2009; 1: 3–8.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Shikh Ye. V. Interaction of components of vitamin-mineral complexes and rational therapy with vitamins. Consilium mеdicum. 2004; 6 (12): 910–912.</mixed-citation><mixed-citation xml:lang="en">Shikh Ye. V. Interaction of components of vitamin-mineral complexes and rational therapy with vitamins. Consilium mеdicum. 2004; 6 (12): 910–912.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Klyuchnikov S. O., Prodeus A. P., Snimshchikova I. A. Clinical and immunological substantiation of reasonability of beta-carotene use in pre-schoolchildren. Voprosi sovremennoi pediatrii — Current Pediatrics. 2010; 9 (1): 22–26.</mixed-citation><mixed-citation xml:lang="en">Klyuchnikov S. O., Prodeus A. P., Snimshchikova I. A. Clinical and immunological substantiation of reasonability of beta-carotene use in pre-schoolchildren. Voprosi sovremennoi pediatrii — Current Pediatrics. 2010; 9 (1): 22–26.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Azova Ye. A., Vorobyova V. A., Mitroshina L. A., Azov N. A., Novopoltseva Ye. G., Belotserkovskaya O.Ye. Experience of treatment with “Vetoron for children” in complex treatment of acute respiratory infections in frequently ailing children in ambulatory. Local pediatrician. 2011; 6: 10–11.</mixed-citation><mixed-citation xml:lang="en">Azova Ye. A., Vorobyova V. A., Mitroshina L. A., Azov N. A., Novopoltseva Ye. G., Belotserkovskaya O.Ye. Experience of treatment with “Vetoron for children” in complex treatment of acute respiratory infections in frequently ailing children in ambulatory. Local pediatrician. 2011; 6: 10–11.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
