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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vsp</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы современной педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Current Pediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-5527</issn><issn pub-type="epub">1682-5535</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/vsp.v12i2.629</article-id><article-id custom-type="elpub" pub-id-type="custom">vsp-355</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В ПОМОЩЬ  ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>A DOCTOR’S AID</subject></subj-group></article-categories><title-group><article-title>Возможности моделирования состава детских молочных смесей за счет введения функциональных нутриентов</article-title><trans-title-group xml:lang="en"><trans-title>Possibilities of modeling of milk formulas composition by adding functional nutrients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лукоянова</surname><given-names>О. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Lukoyanova</surname><given-names>O. L.</given-names></name></name-alternatives><bio xml:lang="en"><p>Contacts: Lukoyanova Olga Leonidovna, PhD, MD, senior scientific worker, Department of Nutrition of Healthy and Sick Child, Scientific Center of Children’s Health, Russian Academy of Medical Sciences Address: 119991, Moscow, Lomonosovskiy Prospect, 2, bldg. 1, Tel.: (499) 132-26-00, e-mail: anlouk@yandex.ru</p></bio><email xlink:type="simple">anlouk@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Боровик</surname><given-names>Т. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Borovik</surname><given-names>T. E.</given-names></name></name-alternatives><email xlink:type="simple">anlouk@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бушуева</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bushueva</surname><given-names>T. V.</given-names></name></name-alternatives><email xlink:type="simple">anlouk@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Звонкова</surname><given-names>Н. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Zvonkova</surname><given-names>N. G.</given-names></name></name-alternatives><email xlink:type="simple">anlouk@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семенова</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Semenova</surname><given-names>N. N.</given-names></name></name-alternatives><email xlink:type="simple">anlouk@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скворцова</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Skvortsova</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">anlouk@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Степанова</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Stepanova</surname><given-names>T. N.</given-names></name></name-alternatives><email xlink:type="simple">anlouk@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Научный центр здоровья детей РАМН, Москва<country>Россия</country></aff><aff xml:lang="en">Scientific Centre of Children Health RAMS, Moscow<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Научный центр здоровья детей РАМН, Москва;&#13;
Первый Московский государственный медицинский университет им. И.М. Сеченова<country>Россия</country></aff><aff xml:lang="en">Scientific Centre of Children Health RAMS, Moscow; &#13;
I.M. Sechenov First Moscow State Medical University, Moscow<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>19</day><month>03</month><year>2013</year></pub-date><volume>12</volume><issue>2</issue><issue-title>Вопросы современной педиатрии</issue-title><fpage>114</fpage><lpage>122</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лукоянова О.Л., Боровик Т.Э., Бушуева Т.В., Звонкова Н.Г., Семенова Н.Н., Скворцова В.А., Степанова Т.Н., 2013</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Лукоянова О.Л., Боровик Т.Э., Бушуева Т.В., Звонкова Н.Г., Семенова Н.Н., Скворцова В.А., Степанова Т.Н.</copyright-holder><copyright-holder xml:lang="en">Lukoyanova O.L., Borovik T.E., Bushueva T.V., Zvonkova N.G., Semenova N.N., Skvortsova V.A., Stepanova T.N.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vsp.spr-journal.ru/jour/article/view/355">https://vsp.spr-journal.ru/jour/article/view/355</self-uri><abstract/><trans-abstract xml:lang="en"><p>The data on necessity of certain functional nutrients adding to the composition of milk formulas, technological difficulties of their isolation and innovative methods used in this field are shown in the article. Aim: to study tolerance to investigated milk formulas and to evaluate their influence on physical development of infants younger than 1 year. Patients and methods: the results of the clinical observation of 60 healthy children (36 girls and 24 boys) at the age younger than 1 year old fed with the studied dry adapted milk formulas are shown. Criteria of feeding efficacy were: evaluation of the tolerance to the formulas, dynamics of height and weight values, results of clinical blood sample, feces microscopy as well as protein efficacy coefficient. Results: the authors established good tolerance to the studied products, appropriate improvement of height and weight values, accordance of the results of clinical blood samples to the mean age norms, absence of pathological changes in coprological tests in all of the observed children during the whole follow-up. Conclusions: the investigated formulas have optimal balanced composition of nutrients, positive influence on physical development and are well-tolerated by children, which make possible their usage in feeding of infants who cannot be breast-fed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>функциональные компоненты пищи</kwd><kwd>грудное молоко</kwd><kwd>детские молочные смеси</kwd><kwd>искусственное вскармливание</kwd></kwd-group><kwd-group xml:lang="en"><kwd>functional nutrients</kwd><kwd>breast milk</kwd><kwd>milk formulas</kwd><kwd>artificial feeding</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lukoyanova O. L., Borovik T. E., Skvortsova V. A., Ladodo K. S. Preconditions for the creation of modern adapted milk formula with symbiotic effects. Questions of children’s dietology. 2010; 8 (4): 49–54.</mixed-citation><mixed-citation xml:lang="en">Lukoyanova O. 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