vspВопросы современной педиатрииCurrent Pediatrics1682-55271682-5535Издательство «ПедиатрЪ»10.15690/vsp.v23i6.2832vsp-3651Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEWУвеиты, ассоциированные с ювенильным идиопатическим артритом. Современное состояние проблемы: вопросы эпидемиологии, патогенеза и клиникиJuvenile Idiopathic Arthritis Associated Uveitis. Current Status: Epidemiology, Pathogenesis, and Clinical Issueshttps://orcid.org/0000-0002-1061-6074ЯковлевА. А.YakovlevAlexandr A.

Санкт-Петербург

Saint-Petersburg

https://orcid.org/0000-0001-6758-6999НикитинаТ. Н.NikitinaTatiana N.

Санкт-Петербург

Saint-Petersburg

https://orcid.org/0000-0002-1180-8086КостикМ. М.KostikMikhail M.

Михаил Михайлович Костик - доктор медицинских наук, профессор кафедры госпитальной педиатрии 

194100, Санкт-Петербург, ул. Литовская, д. 2

 тел.: +7 (812) 416-52-96

Saint-Petersburg

kost-mikhail@yandex.ruФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет» Минздрава РоссииРоссияSaint-Petersburg State Pediatric Medical UniversityRussian Federation202402012025236424437Copyright © Яковлев А.А., Никитина Т.Н., Костик М.М., 20242024Яковлев А.А., Никитина Т.Н., Костик М.М.Yakovlev A.A., Nikitina T.N., Kostik M.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vsp.spr-journal.ru/jour/article/view/3651

Увеит является наиболее частым внесуставным проявлением ювенильного идиопатического артрита (ЮИА) и при отсутствии адекватного лечения приводит к развитию серьезных осложнений со стороны органа зрения, таких как катаракта, вторичная глаукома, отслойка сетчатки, лентовидная дистрофия роговицы. Наличие данной патологии снижает качество жизни пациентов и может приводить к значительными социально-экономическими потерям, как из-за прямых медицинских затрат, так и за счет потери трудоспособности, поскольку способно повлечь за собой полную потерю зрения. Увеиты детского возраста составляют примерно 5–10% от числа всех увеитов в популяции, однако их число увеличивается в последние годы. Этиология и патогенез увеита, ассоциированного с ЮИА, остаются недостаточно изученными, несмотря на довольно известную взаимосвязь увеита с ЮИА. Увеиты у детей сложны в диагностике в рутинной педиатрической практике как из-за особенностей течения (бессимптомное/малосимптомное), так и по причине сложностей в вербальной коммуникации и обследовании (дети раннего возраста), что представляет серьезную клиническую проблему. В статье представлены современные данные, касающиеся эпидемиологии, патогенеза, клинических проявлений, терминологии ЮИА-ассоциированных увеитов.

Uveitis is the most common extraarticular manifestation of juvenile idiopathic arthritis (JIA) and with no adequate management results in serious eye complications such as cataracts, secondary glaucoma, retinal detachment, and linear corneal dystrophy. This pathology reduces patients’ quality of life and can lead to significant social and economic losses, both due to direct health costs and due to disability (total loss of sight). Childhood uveitis accounts for approximately 5–10% of all uveitis in global population, however their prevalence has been increasing in recent years. The etiology and pathogenesis of JIA-associated uveitis remains poorly studied despite the well-known correlation of uveitis with JIA. Uveitis in children is difficult to diagnose in routine pediatric practice, both due to its course (asymptomatic/mild), and due to challenging verbal communication and examination (young children), which poses significant clinical problem. This article presents current data on the epidemiology, pathogenesis, clinical manifestations, and terminology of JIA-associated uveitis.

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The authors declare that there are no conflicts of interest present.