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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vsp</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы современной педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Current Pediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-5527</issn><issn pub-type="epub">1682-5535</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/vsp.v12i1.568</article-id><article-id custom-type="elpub" pub-id-type="custom">vsp-379</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБМЕН ОПЫТОМ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXCHANGE OF EXPERIENCE</subject></subj-group></article-categories><title-group><article-title>НОВЫЕ ВОЗМОЖНОСТИ АНТИБИОТИКОТЕРАПИИ ПРИ ОСТРОЙ И ХРОНИЧЕСКОЙ РЕСПИРАТОРНОЙ ПАТОЛОГИИ У ДЕТЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>NEW POSSIBILITIES OF ANTIBACTERIAL TREATMENT IN ACUTE AND CHRONIC RESPIRATORY DISORDERS IN CHILDREN</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Симонова</surname><given-names>О. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Simonova</surname><given-names>O. I.</given-names></name></name-alternatives><bio xml:lang="ru"/><email xlink:type="simple">oisimonova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лазарева</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lazareva</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">oisimonova@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мотузова</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Motuzova</surname><given-names>O. V.</given-names></name></name-alternatives><email xlink:type="simple">oisimonova@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пономаренко</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ponamorenko</surname><given-names>O. A.</given-names></name></name-alternatives><email xlink:type="simple">oisimonova@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Катосова</surname><given-names>Л. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Katosova</surname><given-names>L. K.</given-names></name></name-alternatives><email xlink:type="simple">oisimonova@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чистякова</surname><given-names>В. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Chistyakova</surname><given-names>V. P.</given-names></name></name-alternatives><email xlink:type="simple">oisimonova@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Буркина</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Burkina</surname><given-names>N. I.</given-names></name></name-alternatives><email xlink:type="simple">oisimonova@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научный центр здоровья детей РАМН, Москва;&#13;
Первый Московский государственный медицинский университет им. И.М. Сеченова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Centre of Children Health, RAMS, Moscow;&#13;
I.M. Sechenov First State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научный центр здоровья детей РАМН, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Centre of Children Health, RAMS, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Научный центр здоровья детей РАМН, Москва,</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Centre of Children Health, RAMS, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>03</day><month>02</month><year>2013</year></pub-date><volume>12</volume><issue>1</issue><issue-title>Вопросы современной педиатрии</issue-title><fpage>123</fpage><lpage>130</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Симонова О.И., Лазарева А.В., Мотузова О.В., Пономаренко О.А., Катосова Л.К., Чистякова В.П., Буркина Н.И., 2013</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Симонова О.И., Лазарева А.В., Мотузова О.В., Пономаренко О.А., Катосова Л.К., Чистякова В.П., Буркина Н.И.</copyright-holder><copyright-holder xml:lang="en">Simonova O.I., Lazareva A.V., Motuzova O.V., Ponamorenko O.A., Katosova L.K., Chistyakova V.P., Burkina N.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vsp.spr-journal.ru/jour/article/view/379">https://vsp.spr-journal.ru/jour/article/view/379</self-uri><abstract><p>Представлены данные о современном микробном пейзаже детей с острой и хронической респираторной патологией, динамика чувствительности микрофлоры за последние годы к часто применяемым антибиотикам. Приводятся принципы выбора антибиотика и контроля его эффективности, особенности применения у детей, частые побочные эффекты. Рассмотрены новые аспекты применения комбинированных антибактериальных препаратов ― экоантибиотиков. Включение в их состав лактулозы ангидро позволяет достичь высокой микробиологической эффективности и не вызывает антибиотик-ассоциированной диареи, что очень существенно в педиатрической практике.</p><p> </p></abstract><trans-abstract xml:lang="en"><p>The authors show the data on current microbiological pattern in children with acute and chronic respiratory disorders and dynamics of microflora susceptibility to the most frequently used antibiotics over recent years. The principles of antibiotic choice and control for their efficiency, peculiarities of their usage in children and the most common side effects are given. New aspects of the usage of combined antibacterial agents - ecoantibiotics – are discussed. Including of the Lactulose Anhydro into their composition allows to achieve high microbiological efficacy and does not cause antibiotic-induced diarrhea, which has a great importance in pediatric practice.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>антибактериальная терапия</kwd><kwd>экоантибиотики</kwd><kwd>лечение острых</kwd><kwd>рецидивирующих и хронических респираторных заболеваний</kwd><kwd>хронический бронхит</kwd><kwd>обострение хронического бронхолегочного процесса</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>antibacterial treatment</kwd><kwd>ecoantibiotics</kwd><kwd>treatment of acute</kwd><kwd>recurrent and chronic respiratory disorders</kwd><kwd>chronic bronchitis</kwd><kwd>relapse of chronic bronchopulmonary disorder</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Tatochenko V. K. Bronchites in children. 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