vspВопросы современной педиатрииCurrent Pediatrics1682-55271682-5535Издательство «ПедиатрЪ»10.15690/vsp.v12i1.570vsp-381Research ArticleОБМЕН ОПЫТОМEXCHANGE OF EXPERIENCEОПТИМИЗАЦИЯ ПРОТИВОВИРУСНОЙ ТЕРАПИИ ГРИППА У ДЕТЕЙ И ВЗРОСЛЫХOPTIMIZATION OF ANTI-VIRAL THERAPY OF INFLUENZA IN CHILDREN AND ADULTSИсаковВ. А.IsakovV. A.

Isakov Valeriy Aleksandrovich, PhD, MD, professor, Chair of Infectious Diseases and Epidemiology With Course of HIV-Medicine, Academician I.P. Pavlov St.-Petersburg State Medical University, head of Department of Viral Infections

issakov1945@yandex.ruБеляеваТ. В.BelyaevaT. V.issakov1945@yandex.ruАфанасьеваО. И.Afanas'evaO. I.issakov1945@yandex.ruСанкт-Петербургский государственный медицинский университет им. акад. И.П. ПавловаРоссияSt. Petersburg State Medical University named after I.P. Pavlov,Russian FederationСанкт-Петербургский государственный медицинский университет им. акад. И.П. ПавловаРоссияSt. Petersburg State Medical University named after I.P. PavlovRussian FederationНИИ гриппа, Санкт-ПетербургРоссияResearch Institute of Influenza, St. PetersburgRussian Federation201303022013121Вопросы современной педиатрии136140Copyright © Исаков В.А., Беляева Т.В., Афанасьева О.И., 20132013Исаков В.А., Беляева Т.В., Афанасьева О.И.Isakov V.A., Belyaeva T.V., Afanas'eva O.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vsp.spr-journal.ru/jour/article/view/381

У 48 детей, получавших в составе комплексной терапии смешанных инфекций инозина пранобекс, отмечена достоверно более значимая динамика основных клинических симптомов, чем у 16 детей группы сравнения. Это сопровождалось положительными сдвигами серологических маркеров, в частности, основных герпесвирусных инфекций (вируса Эпштейна–Барр и вируса простого герпеса типов 1, 2), что обусловлено бифункциональной активностью (противовирусной и иммуномодулирующей) инозина пранобекса.

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The authors declare that there are no conflicts of interest present.