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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vsp</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы современной педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Current Pediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-5527</issn><issn pub-type="epub">1682-5535</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/vsp.v11i4.364</article-id><article-id custom-type="elpub" pub-id-type="custom">vsp-459</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБМЕН ОПЫТОМ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXCHANGE OF EXPERIENCE</subject></subj-group></article-categories><title-group><article-title>ОПРЕДЕЛЕНИЕ ЗНАЧИМОСТИ ФАКТОРОВ РИСКА РАЗВИТИЯ ГНОЙНО-СЕПТИЧЕСКИХ ОСЛОЖНЕНИЙ ПОСЛЕ ХИРУРГИЧЕСКОГО ВМЕШАТЕЛЬСТВА У НОВОРОЖДЕННЫХ МЕТОДАМИ МНОГОФАКТОРНОГО АНАЛИЗА</article-title><trans-title-group xml:lang="en"><trans-title>THE IMPORTANCE OF THE RISK FACTORS OF PURULENT-SEPTIC COMPLICATIONS DEVELOPMENT</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Обедин</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Obedin</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>Aleksandr Obedin, Candidate of Medical Science, associate professor of pediatric surgery with a course of anesthesiology and resuscitation</p></bio><email xlink:type="simple">volander@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Минаев</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Minaev</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">volander@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Киргизов</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kirgizov</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">volander@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Александров</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Aleksandrov</surname><given-names>A. E.</given-names></name></name-alternatives><email xlink:type="simple">volander@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Товкань</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tovkan</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">volander@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Романеева</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Romaneeva</surname><given-names>N. M.</given-names></name></name-alternatives><email xlink:type="simple">volander@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хоранова</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Khoranova</surname><given-names>T. A.</given-names></name></name-alternatives><email xlink:type="simple">volander@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чинтаева</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Сhitaeva</surname><given-names>L. A.</given-names></name></name-alternatives><email xlink:type="simple">volander@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ставропольская государственная медицинская академия</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Stavropol State Medical Academy, Ministry of Healthcare and Social Development of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научный центр здоровья детей РАМН, Москва&#13;
Первый Московский государственный медицинский университет им. И.М. Сеченова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Centre of Children Health, RAMS, Moscow&#13;
I.M. Sechenov First Moscow State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Научный центр здоровья детей РАМН, Москва;&#13;
Первый Московский государственный медицинский университет им. И.М. Сеченова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Centre of Children Health, RAMS, Moscow&#13;
I.M. Sechenov First Moscow State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Краевая детская клиническая больница, Ставрополь</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Territorial Children Clinical Hospital, Stavropol</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>19</day><month>07</month><year>2012</year></pub-date><volume>11</volume><issue>4</issue><issue-title>Вопросы современной педиатрии</issue-title><fpage>90</fpage><lpage>94</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Обедин А.Н., Минаев С.В., Киргизов И.В., Александров А.Е., Товкань Е.А., Романеева Н.М., Хоранова Т.А., Чинтаева Л.А., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Обедин А.Н., Минаев С.В., Киргизов И.В., Александров А.Е., Товкань Е.А., Романеева Н.М., Хоранова Т.А., Чинтаева Л.А.</copyright-holder><copyright-holder xml:lang="en">Obedin A.N., Minaev S.V., Kirgizov I.V., Aleksandrov A.E., Tovkan E.A., Romaneeva N.M., Khoranova T.A., Сhitaeva L.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vsp.spr-journal.ru/jour/article/view/459">https://vsp.spr-journal.ru/jour/article/view/459</self-uri><abstract><p>Изучено влияние некоторых факторов, влияющих на развитие гнойно-септических осложнений у новорожденных с врожденными пороками развития желудочно-кишечного тракта. В качестве независимых переменных были выбраны как бинарные, так и численные переменные. Кроме того, изучалось сочетанное действие различных факторов догоспитального этапа оказания помощи, показавших при предварительном анализе высокую вероятность влияния на развитие осложнений. Общее число различных предикторов развития гнойно-септического осложнения после проведения хирургического вмешательства, подвергнутых анализу, составило 42. Выделено 3 основных группы влияющих факторов, которые связаны с: 1) видом проводимой послеоперационной аналгезии и полом ребенка; 2) нарушением проницаемости кишечной стенки; 3) расстройствами перфузии стенки кишечника. Для создания подходящей модели был применен метод логистической регрессии с нормализацией показателей по методу квази-Ньютона. Данная модель обладает достаточно хорошими возможностями по предсказанию как положительных (наличие риска гнойно-септического осложнения), так и отрицательных (отсутствие такого риска) результатов. Процент правильно предсказанных случаев осложнений составляет 76%, а предсказание отсутствия заболевания достигает вероятности 84%.</p><p>Ключевые слова: новорожденные, врожденные пороки развития желудочно-кишечного тракта, I-FABP.</p></abstract><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>новорожденные</kwd><kwd>врожденные пороки развития желудочно-кишечного тракта</kwd><kwd>I-FABP</kwd></kwd-group><kwd-group xml:lang="en"><kwd>newborns</kwd><kwd>congenital gastro-intestinal tract malmorations</kwd><kwd>I-FABP</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ахмадеева Э. Н., Фатыхова А. И. Инфузионная терапия и парентеральное питание в неонатологии. Пособие для врачей. Уфа: Издательство «VerteX». 2005. С. 1–34.</mixed-citation><mixed-citation xml:lang="en">Ахмадеева Э. Н., Фатыхова А. И. Инфузионная терапия и парентеральное питание в неонатологии. 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