<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vsp</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы современной педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Current Pediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-5527</issn><issn pub-type="epub">1682-5535</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/vsp.v11i4.368</article-id><article-id custom-type="elpub" pub-id-type="custom">vsp-463</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБМЕН ОПЫТОМ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXCHANGE OF EXPERIENCE</subject></subj-group></article-categories><title-group><article-title>ГРУДНОЕ МОЛОКО КАК ЭТАЛОННАЯ МОДЕЛЬ ДЛЯ СОЗДАНИЯ ДЕТСКИХ МОЛОЧНЫХ СМЕСЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>BREAST MILK AS A GOLD STANDARD FOR DEVELOPMENT OF ARTIFICIAL MILK FORMULAS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лукоянова</surname><given-names>О. л</given-names></name><name name-style="western" xml:lang="en"><surname>Lukoyanova</surname><given-names>O. L.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>Ol’ga Lukoyanova, Candidate of Medical Science, chief research scientist of the department of nutrition of healthy and sick child of Scientific Center of Children’s Health</p></bio><email xlink:type="simple">anlouk@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научный центр здоровья детей РАМН, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Centre of Children Health RAMS, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>19</day><month>07</month><year>2012</year></pub-date><volume>11</volume><issue>4</issue><issue-title>Вопросы современной педиатрии</issue-title><fpage>111</fpage><lpage>115</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лукоянова О.л., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Лукоянова О.л.</copyright-holder><copyright-holder xml:lang="en">Lukoyanova O.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vsp.spr-journal.ru/jour/article/view/463">https://vsp.spr-journal.ru/jour/article/view/463</self-uri><abstract><p>В статье представлены современные данные научных исследований о составе грудного молока, дано обоснование необходимости введения в детские молочные смеси тех или иных функциональных компонентов, обнаруженных в нем. Также приведены основные принципы адаптации детских молочных смесей.</p></abstract><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>грудное молоко</kwd><kwd>грудное вскармливание</kwd><kwd>детские молочные смеси</kwd><kwd>нуклеотиды</kwd><kwd>длинноцепочечные полиненасыщенные жирные кислоты</kwd><kwd>олигосахариды</kwd></kwd-group><kwd-group xml:lang="en"><kwd>breast milk</kwd><kwd>breast feeding</kwd><kwd>artificial milk formulas</kwd><kwd>nucleotides</kwd><kwd>long chain polyunsaturated fatty acids</kwd><kwd>oligosaccharides</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Koyashiki G., Paoliello M., Paul B. Lead levels in human milk and children’s health risk: A systematic review. Tchounwou. Rev. Environ. Health. 2010; 25 (3): 243–253.</mixed-citation><mixed-citation xml:lang="en">Koyashiki G., Paoliello M., Paul B. Lead levels in human milk and children’s health risk: A systematic review. Tchounwou. Rev. Environ. Health. 2010; 25 (3): 243–253.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Руководство по детскому питанию / под ред. акад. РАМН В. А. Тутельяна и проф. И. Я. Коня. М.: МИА. 2004. 662 с.</mixed-citation><mixed-citation xml:lang="en">Руководство по детскому питанию / под ред. акад. РАМН В. А. Тутельяна и проф. И. Я. Коня. М.: МИА. 2004. 662 с.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Pirila S., Taskinen M., Viljakainen H. et al. Infant milk feeding influences adult bone health: A prospective study from birth to 32 years. PLoS One. 2011; 6 (4): 19068.</mixed-citation><mixed-citation xml:lang="en">Pirila S., Taskinen M., Viljakainen H. et al. Infant milk feeding influences adult bone health: A prospective study from birth to 32 years. PLoS One. 2011; 6 (4): 19068.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Trabulsi J., Capeding R., Lebumfacil J. et al. Effect of an -lactalbumin-enriched infant formula with lower protein on growth. Eur. J. Clin. Nutr. 2011; 65 (2): 167–174.</mixed-citation><mixed-citation xml:lang="en">Trabulsi J., Capeding R., Lebumfacil J. et al. Effect of an -lactalbumin-enriched infant formula with lower protein on growth. Eur. J. Clin. Nutr. 2011; 65 (2): 167–174.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Froehlich J. W., Dodds E. D., Barboza M. et al. Glycoprotein expression in human milk during lactation. J. Agric. Food Chem. 2010; 58 (10): 6440–6448. Doi: 10.1021/jf100112x.</mixed-citation><mixed-citation xml:lang="en">Froehlich J. W., Dodds E. D., Barboza M. et al. Glycoprotein expression in human milk during lactation. J. Agric. Food Chem. 2010; 58 (10): 6440–6448. Doi: 10.1021/jf100112x.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Hettinga K., van Valenberg H., de Vries S. et al. The host defense proteome of human and bovine milk. PLoS One. 2011; 6 (4): 19433.</mixed-citation><mixed-citation xml:lang="en">Hettinga K., van Valenberg H., de Vries S. et al. The host defense proteome of human and bovine milk. PLoS One. 2011; 6 (4): 19433.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Liao Y., Alvarado R., Phinney B., Lonnerdal B. Proteomic characterization of human milk whey proteins during a twelve-month lactation period. J. Proteome Res. 2011; 10 (4): 1746–1754.</mixed-citation><mixed-citation xml:lang="en">Liao Y., Alvarado R., Phinney B., Lonnerdal B. Proteomic characterization of human milk whey proteins during a twelve-month lactation period. J. Proteome Res. 2011; 10 (4): 1746–1754.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Carver J. D., Walker W. A. The role of nucleotides in human nutrition. Nutr. Biochem. 1995; 6: 58–72.</mixed-citation><mixed-citation xml:lang="en">Carver J. D., Walker W. A. The role of nucleotides in human nutrition. Nutr. Biochem. 1995; 6: 58–72.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Singhal A., Macfarlane G., Macfarlane S. et al. Dietary nucleotides and fecal microbiota in formula-fed infant: a randomized controlled trial. Am. J. Clin. Nutr. 2008; 87 (6): 785–792.</mixed-citation><mixed-citation xml:lang="en">Singhal A., Macfarlane G., Macfarlane S. et al. Dietary nucleotides and fecal microbiota in formula-fed infant: a randomized controlled trial. Am. J. Clin. Nutr. 2008; 87 (6): 785–792.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Захарова И. Н., Лыкина Е. В., Коровина Н. А. Значение нуклеотидов в питании детей раннего возраста. Consilium medicum. 2004; 6 (2): 15–18.</mixed-citation><mixed-citation xml:lang="en">Захарова И. Н., Лыкина Е. В., Коровина Н. А. Значение нуклеотидов в питании детей раннего возраста. Consilium medicum. 2004; 6 (2): 15–18.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Zavaleta N., Kvistgaard A. S., Graverholt G. et al. Efficacy of a complementary food enriched with a milk fat globule membrane protein fraction on diarrhea, anemia and micronutrient status in infants. J. Pediatr. Gastroenterol. Nutr. 2011; 2: 231–236.</mixed-citation><mixed-citation xml:lang="en">Zavaleta N., Kvistgaard A. S., Graverholt G. et al. Efficacy of a complementary food enriched with a milk fat globule membrane protein fraction on diarrhea, anemia and micronutrient status in infants. J. Pediatr. Gastroenterol. Nutr. 2011; 2: 231–236.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Children’s health, The Nation’s wealth: assessing and improving child health. Washington, DC: Institute of Medicine. 2004. URL: http://www.nap.edu/catalog/10886.html</mixed-citation><mixed-citation xml:lang="en">Children’s health, The Nation’s wealth: assessing and improving child health. Washington, DC: Institute of Medicine. 2004. URL: http://www.nap.edu/catalog/10886.html</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">National Research Council (US); Institute of Medicine (US). Washington D. C.: National Academic Press (US). 2004.</mixed-citation><mixed-citation xml:lang="en">National Research Council (US); Institute of Medicine (US). Washington D. C.: National Academic Press (US). 2004.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Hadders-Algra M. Effect of long-chain polyunsaturated fatty acid supplementation on neurodevelopmental outcome in fullterm infants. Nutrients. 2010; 2 (8): 790–804.</mixed-citation><mixed-citation xml:lang="en">Hadders-Algra M. Effect of long-chain polyunsaturated fatty acid supplementation on neurodevelopmental outcome in fullterm infants. Nutrients. 2010; 2 (8): 790–804.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Laiho K., Lampi A. M., Hamalainen M. et al. Breast milk fatty acids, eicosanoids, and cytokines in mothers with and without allergic disease. Pediatr. Res. 2003; 53 (4): 642–647.</mixed-citation><mixed-citation xml:lang="en">Laiho K., Lampi A. M., Hamalainen M. et al. Breast milk fatty acids, eicosanoids, and cytokines in mothers with and without allergic disease. Pediatr. Res. 2003; 53 (4): 642–647.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Morale S. E., Hoffman D.R., Castaneda Y. S. et al. Duration of long-chain polyunsaturated fatty acids availability in the diet and visual activity. Early Hum. Dev. 2005; 81: 197–203.</mixed-citation><mixed-citation xml:lang="en">Morale S. E., Hoffman D.R., Castaneda Y. S. et al. Duration of long-chain polyunsaturated fatty acids availability in the diet and visual activity. Early Hum. Dev. 2005; 81: 197–203.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Forsyth J. S., Willatts P., Agostoni S. et al. Long-chain polyunsaturated fatty acids supplementation in infant formula and blood pressure in later childhood: follow up a randomized controlled trial. BMJ. 2003; 326: 953–957.</mixed-citation><mixed-citation xml:lang="en">Forsyth J. S., Willatts P., Agostoni S. et al. Long-chain polyunsaturated fatty acids supplementation in infant formula and blood pressure in later childhood: follow up a randomized controlled trial. BMJ. 2003; 326: 953–957.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Кoletzko B. et al. Word Association of Perinatal Medicine Dietary Guidelines Working Group. J. Perinat. Med. 2008; 36 (1): 5–14.</mixed-citation><mixed-citation xml:lang="en">Кoletzko B. et al. Word Association of Perinatal Medicine Dietary Guidelines Working Group. J. Perinat. Med. 2008; 36 (1): 5–14.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Yakes E. A., Arsenault J.E., Islam M. M. et al. Dietary intake of polyunsaturated fatty acids (PUFA) among breastfeeding and nonbreastfeeding 24–48 month old children in Bangladesh. J. Pediatr. Gastroenterol. Nutr. 2011; 52 (3): 351–359.</mixed-citation><mixed-citation xml:lang="en">Yakes E. A., Arsenault J.E., Islam M. M. et al. Dietary intake of polyunsaturated fatty acids (PUFA) among breastfeeding and nonbreastfeeding 24–48 month old children in Bangladesh. J. Pediatr. Gastroenterol. Nutr. 2011; 52 (3): 351–359.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Vos A.P., Rabet L. M. et al. Иммуномодулирующие свойства и возможные механизмы действия неперевариваемых углеводов. Педиатрия. 2008; 87 (3): 111–116.</mixed-citation><mixed-citation xml:lang="en">Vos A.P., Rabet L. M. et al. Иммуномодулирующие свойства и возможные механизмы действия неперевариваемых углеводов. Педиатрия. 2008; 87 (3): 111–116.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Moro G., Arslanoglu S., Stahl B. et al. A mixture of prebiotic oligosaccharides reduces the incidence of atopic dermatitis during the six months of of age. Arch. Dis. Child. 2006; 91 (10): 814–819.</mixed-citation><mixed-citation xml:lang="en">Moro G., Arslanoglu S., Stahl B. et al. A mixture of prebiotic oligosaccharides reduces the incidence of atopic dermatitis during the six months of of age. Arch. Dis. Child. 2006; 91 (10): 814–819.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Fanaro S., Marten B., Bagna R. et al. Galacto-oligosaccharides are bifidogenic and safe at weaning: A double-blind randomized multicenter study. J. Pediatric Gastroenterol. Nutr. 2008; 3: 345–352.</mixed-citation><mixed-citation xml:lang="en">Fanaro S., Marten B., Bagna R. et al. Galacto-oligosaccharides are bifidogenic and safe at weaning: A double-blind randomized multicenter study. J. Pediatric Gastroenterol. Nutr. 2008; 3: 345–352.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
