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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vsp</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы современной педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Current Pediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-5527</issn><issn pub-type="epub">1682-5535</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/vsp.v11i3.291</article-id><article-id custom-type="elpub" pub-id-type="custom">vsp-480</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERATURE REVIEW</subject></subj-group></article-categories><title-group><article-title>ЭФФЕКТИВНОСТЬ ПРОФИЛАКТИКИ ПНЕВМОКОККОВЫХ ИНФЕКЦИЙ У ИММУНОКОМПРОМЕТИРОВАННЫХ БОЛЬНЫХ</article-title><trans-title-group xml:lang="en"><trans-title>EFFICACY OF PNEUMOCOCCAL INFECTIONS PROPHYLAXIS IN IMMUNOCOMPROMISED PATIENTS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галкина-Лазарева</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Galkina-Lazareva</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Галкина-Лазарева Елизавета Всеволодовна, кандидат медицинских наук, заведующая педиатрическим отделением клиники Alliance Francaise ООО «РУСАВИАМЕД»</p></bio><bio xml:lang="en"><p>Galkina-Lazareva Elizaveta Vsevolodovna, MD, Head of the Pediatric Department of Alliance Francaise Hospital LLC «RUSAVIAMED»</p></bio><email xlink:type="simple">egalkina@alliance-f.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Клиника Alliance Francaise ООО «РУСАВИАМЕД», Москва</institution></aff><aff xml:lang="en"><institution>Clinic Alliance Francaise LLC «RUSAVIAMED», Moscow</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>17</day><month>05</month><year>2012</year></pub-date><volume>11</volume><issue>3</issue><issue-title>Вопросы современной педиатрии</issue-title><fpage>12</fpage><lpage>17</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Галкина-Лазарева Е.В., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Галкина-Лазарева Е.В.</copyright-holder><copyright-holder xml:lang="en">Galkina-Lazareva E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vsp.spr-journal.ru/jour/article/view/480">https://vsp.spr-journal.ru/jour/article/view/480</self-uri><abstract><p>Среди иммунокомпрометированных пациентов заболеваемость и смертность от инфекций и их осложнений значительно превышает аналогичный показатель у иммунокомпетентного населения. Необходима разработка четких показаний к вакцинации иммунокопрометированных больных как с врожденными, так и приобретенными иммунодефицитами. Благодаря более широкому применению иммуносупрессивной терапии, внедрению биологических препаратов с антицитокиновым механизмом действия растет число вторично иммунокомпрометированных больных. В настоящем обзоре проанализирован опыт специфической профилактики пневмококковой инфекции у разных групп иммунодефицитных больных.</p></abstract><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>иммунокомпрометированные пациенты</kwd><kwd>первичные иммунодефициты</kwd><kwd>специфическая профилактика пневмококковой инфекции</kwd><kwd>пневмококковая полисахаридная вакцина</kwd></kwd-group><kwd-group xml:lang="en"><kwd>immunocompromised patients</kwd><kwd>primary immunodeficiency</kwd><kwd>specific prophylaxis of pneumococcal infection</kwd><kwd>pneumococcal polysaccharide vaccine</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Эпидемиология и вакцинопрофилактика инфекции, вызываемой Streptococcus pneumoniae. Методические рекомендации МР 3.3.1.0027-11. 2011. 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