<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vsp</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы современной педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Current Pediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-5527</issn><issn pub-type="epub">1682-5535</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/vsp.v11i1.146</article-id><article-id custom-type="elpub" pub-id-type="custom">vsp-524</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В ПОМОЩЬ  ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>A DOCTOR’S AID</subject></subj-group></article-categories><title-group><article-title>СОВРЕМЕННЫЙ ВЗГЛЯД НА ИММУНОМОДУЛИРУЮЩУЮ ТЕРАПИЮ</article-title><trans-title-group xml:lang="en"><trans-title>MODERN APPROACH TOWARDS IMMUNOMODULATION THERAPY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Намазова-Баранова</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Namazova-Baranova</surname><given-names>L. S.</given-names></name></name-alternatives><email xlink:type="simple">namazova@nczd.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вишнева</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vishneva</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>Elena Aleksandrovna Vishneva, MD, senior research scientist of the Department of Hospital-replacing technologies, allergologist and immunologist of the Department of Remedial treatment  of Children with hypersensitivity diseases and diseases of the respiratory system of RI of Preventive Pediatrics and Remedial treatment   of SCCH of RAMS</p></bio><email xlink:type="simple">vishneva@nczd.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Научный центр здоровья детей РАМН, Москва;&#13;
Первый Московский государственный медицинский университет им. И.М. Сеченова<country>Россия</country></aff><aff xml:lang="en">Scientific Centre of Children’s Health RAMS, Moscow;&#13;
Sechenov First Moscow Medical University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Научный центр здоровья детей РАМН, Москва<country>Россия</country></aff><aff xml:lang="en">Scientific Centre of Children’s Health RAMS, Moscow<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>15</day><month>01</month><year>2012</year></pub-date><volume>11</volume><issue>1</issue><issue-title>Вопросы современной педиатрии</issue-title><fpage>143</fpage><lpage>146</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Намазова-Баранова Л.С., Вишнева Е.А., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Намазова-Баранова Л.С., Вишнева Е.А.</copyright-holder><copyright-holder xml:lang="en">Namazova-Baranova L.S., Vishneva E.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vsp.spr-journal.ru/jour/article/view/524">https://vsp.spr-journal.ru/jour/article/view/524</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>дендритные клетки</kwd><kwd>иммуномодуляторы</kwd><kwd>пидотимод</kwd></kwd-group><kwd-group xml:lang="en"><kwd>dendritic cells</kwd><kwd>immunostimulants</kwd><kwd>pidotimod</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Steinman R. M., Banchereau J. Taking Dendritic Cells into Medicine // Nature. — 2007; 449: 419–426.</mixed-citation><mixed-citation xml:lang="en">Steinman R. M., Banchereau J. Taking Dendritic Cells into Medicine // Nature. — 2007; 449: 419–426.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Харит С. М., Начарова Е. П., Намазова-Баранова Л. С. и соавт. Эффективность пидотимода для профилактики респира- торных заболеваний у детей // Детские инфекции. — 2010; 4: 32–36.</mixed-citation><mixed-citation xml:lang="en">Харит С. М., Начарова Е. П., Намазова-Баранова Л. С. и соавт. Эффективность пидотимода для профилактики респира- торных заболеваний у детей // Детские инфекции. — 2010; 4: 32–36.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Sheng К. С., Pietersz G. A., Wright M. D. et al. Dendritic cells: activation and maturation applications for cancer immunotherapy // Curr. Med. Chem. — 2005; 12: 1783–1800.</mixed-citation><mixed-citation xml:lang="en">Sheng К. С., Pietersz G. A., Wright M. D. et al. Dendritic cells: activation and maturation applications for cancer immunotherapy // Curr. Med. Chem. — 2005; 12: 1783–1800.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Аллергия у детей: от теории к практике / под ред. Л. С. Намазовой-Барановой. — М.: Союз педиатров России, 2010–2011. — 668 с.</mixed-citation><mixed-citation xml:lang="en">Аллергия у детей: от теории к практике / под ред. Л. С. Намазовой-Барановой. — М.: Союз педиатров России, 2010–2011. — 668 с.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Donnini A., Argentari K., Mancini R. et al. Phenotype, antigenpresenting capacity, and migration of antigen-presenting cells in young and old age // Exp. Gerontol. — 2002; 37: 1097–1112.</mixed-citation><mixed-citation xml:lang="en">Donnini A., Argentari K., Mancini R. et al. Phenotype, antigenpresenting capacity, and migration of antigen-presenting cells in young and old age // Exp. Gerontol. — 2002; 37: 1097–1112.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Rharbaoui F., Drabner B., Borsutzky S. et al. The mycoplasmaderived lipopeptide MALP-2 is a potent mucosal adjuvant // Eur. J. Immunol. — 2002; 32: 2857–2865.</mixed-citation><mixed-citation xml:lang="en">Rharbaoui F., Drabner B., Borsutzky S. et al. The mycoplasmaderived lipopeptide MALP-2 is a potent mucosal adjuvant // Eur. J. Immunol. — 2002; 32: 2857–2865.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Fiorentini S., Becker P. D., Marini E. et al. HIV-1 matrix protein pl7 modulates in vivo preactivated murine T-cell response and enhances the induction of systemic and mucosal immunity against intranasally co-administered antigens // Viral. Immunol. — 2006; 19: 77–88.</mixed-citation><mixed-citation xml:lang="en">Fiorentini S., Becker P. D., Marini E. et al. HIV-1 matrix protein pl7 modulates in vivo preactivated murine T-cell response and enhances the induction of systemic and mucosal immunity against intranasally co-administered antigens // Viral. Immunol. — 2006; 19: 77–88.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Riboldi P., Gerosa M., Meroni P. L. Pidotimod: a reappraisal // Int. J. Immunopathol. Pharmacol. — 2009; 22 (2): 255–262.</mixed-citation><mixed-citation xml:lang="en">Riboldi P., Gerosa M., Meroni P. L. Pidotimod: a reappraisal // Int. J. Immunopathol. Pharmacol. — 2009; 22 (2): 255–262.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Marelli P., Lupetti A., Senesi S. et al. Potenziamento della resistenza alle infezioni virali e batteriche dopo somministrazione di Pidotimod nel topo // Drugs. Exp. Clin. Res. — 1993; 19: 15–21.</mixed-citation><mixed-citation xml:lang="en">Marelli P., Lupetti A., Senesi S. et al. Potenziamento della resistenza alle infezioni virali e batteriche dopo somministrazione di Pidotimod nel topo // Drugs. Exp. Clin. Res. — 1993; 19: 15–21.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Careddu P., Biolchini A., Alfano S., Zavattini G. Pidotimod in the prophylaxis of recurrent acute tonsillitis in childhood // Adv. Otorhinolaryngol. — 1992; 47: 328–331.</mixed-citation><mixed-citation xml:lang="en">Careddu P., Biolchini A., Alfano S., Zavattini G. Pidotimod in the prophylaxis of recurrent acute tonsillitis in childhood // Adv. Otorhinolaryngol. — 1992; 47: 328–331.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Careddu P. Role of immunoactivation with pidotimod in recurrent respiratory infections in childhood // Drug. Res. — 1994; 44: 1506–1511.</mixed-citation><mixed-citation xml:lang="en">Careddu P. Role of immunoactivation with pidotimod in recurrent respiratory infections in childhood // Drug. Res. — 1994; 44: 1506–1511.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Aivazis V., Hatzimichail A., Papachristou A. et al. Clinical evaluation and changes of the respiratory epithelium function after administration of pidotimod in Greek children with recurrent respiratory tract infections // Minerva Pediatr. — 2002; 54: 315–319.</mixed-citation><mixed-citation xml:lang="en">Aivazis V., Hatzimichail A., Papachristou A. et al. Clinical evaluation and changes of the respiratory epithelium function after administration of pidotimod in Greek children with recurrent respiratory tract infections // Minerva Pediatr. — 2002; 54: 315–319.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Giagulli C., Noerder M., Avolio M. et al. Pidotimod promotes functional maturation of dendritic cells and displays adjuvant properties at the nasal mucosa level // Int. Immunopharmacol. — 2009; 9 (12): 1366–1373.</mixed-citation><mixed-citation xml:lang="en">Giagulli C., Noerder M., Avolio M. et al. Pidotimod promotes functional maturation of dendritic cells and displays adjuvant properties at the nasal mucosa level // Int. Immunopharmacol. — 2009; 9 (12): 1366–1373.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
