vspВопросы современной педиатрииCurrent Pediatrics1682-55271682-5535Издательство «ПедиатрЪ»10.15690/vsp.v14i2.1298vsp-70Research ArticleОБМЕН ОПЫТОМEXCHANGE OF EXPERIENCEБРОНХООБСТРУКТИВНЫЙ СИНДРОМ У ДЕТЕЙ: НОВОЕ РЕШЕНИЕ СТАРОЙ ПРОБЛЕМЫBRONCHIAL OBSTRUCTION IN CHILDREN: A NEW SOLUTION TO AN OLD PROBLEMСимоноваО. И.SimonovaO. I.

доктор медицинских наук, профессор, заведующая отделением пульмонологии и аллергологии Научного центра здоровья детей Адрес: 119991, Москва, Ломоносовский проспект, д. 2, стр. 1, тел.: +7 (499) 134-93-31

oisimonova@mail.ruГориноваЮ. В.GorinovaYu. V.oisimonova@mail.ruАлексееваА. А.AlekseevaA. A.oisimonova@mail.ruТомиловаА. А.TomilovaA. A.oisimonova@mail.ruНаучный центр здоровья детей, Москва, Российская Федерация Первый Московский государственный медицинский университет им. И.М. Сеченова, Российская ФедерацияРоссияScientific Centre of Children’s Health, Moscow, Russian Federation I.M. Sechenov First Moscow State Medical University, Russian FederationRussian FederationНаучный центр здоровья детей, Москва, Российская ФедерацияРоссияScientific Centre of Children’s Health, Moscow, Russian FederationRussian Federation201517042015142Вопросы современной педиатрии276280Copyright © Симонова О.И., Горинова Ю.В., Алексеева А.А., Томилова А.А., 20152015Симонова О.И., Горинова Ю.В., Алексеева А.А., Томилова А.А.Simonova O.I., Gorinova Y.V., Alekseeva A.A., Tomilova A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vsp.spr-journal.ru/jour/article/view/70

Бронхообструктивный синдром — широко распространенное у детей патологическое состояние. К развитию этого синдрома при бронхиальной астме приводит аллергическое воспаление слизистой оболочки дыхательных путей с участием лейкотриенов. Установлено, что блокирование лейкотриеновых рецепторов с помощью препаратов монтелукаста оказывает терапевтическое воздействие, в т. ч. и у детей с возраста 2 лет. Препараты хорошо ими переносятся, способны предупреждать постнагрузочный бронхоспазм и в некоторых клинических ситуациях могут использоваться в качестве альтернативы глюкокортикоидам.

 

Bronchial obstruction is a widespread pathological condition in children. The development of this syndrome in bronchial asthma is caused by an allergic inflammation of the mucous membranes of the respiratory tract with the participation of leukotrienes. It is found that the blocking of leukotriene receptors using the montelukast drugs has a therapeutic effect, including in children at the age of 2 and above. The drugs are well tolerated by children, can prevent a post-exertional bronchospasm and in some clinical situations can be used as an alternative to glucocorticoids.

 

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The authors declare that there are no conflicts of interest present.