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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vsp</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы современной педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Current Pediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-5527</issn><issn pub-type="epub">1682-5535</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">vsp-757</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>НАРУШЕНИЕ МИНЕРАЛИЗАЦИИ КОСТНОЙ ТКАНИ У ДЕТЕЙ С ВОСПАЛИТЕЛЬНЫМИ ЗАБОЛЕВАНИЯМИ КИШЕЧНИКА</article-title><trans-title-group xml:lang="en"><trans-title>MINERALIZATION DISORDER OF OSSEOUS TISSUE AMONG THE CHILDREN, SUFFERING FROM INFLAMMATORY BOWEL DISEASES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яблокова</surname><given-names>Е.А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yablokova</surname><given-names>E.A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горелов</surname><given-names>А.В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gorelov</surname><given-names>A.V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чумакова</surname><given-names>О.В.</given-names></name><name name-style="western" xml:lang="en"><surname>Chumakova</surname><given-names>O.V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ратникова</surname><given-names>М.А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ratnikova</surname><given-names>M.A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сичинава</surname><given-names>И.В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sichinava</surname><given-names>I.V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Московская медицинская академия им. И.М. Сеченова<country>Россия</country></aff><aff xml:lang="en">I.M. Sechenov Moscow Medical Academy<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Научный центр здоровья детей РАМН, Москва<country>Россия</country></aff><aff xml:lang="en">Scientific Center of Children's Health of Russian Academy of Medical Sciences, Moscow<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2006</year></pub-date><pub-date pub-type="epub"><day>09</day><month>09</month><year>2015</year></pub-date><volume>5</volume><issue>4</issue><issue-title>Вопросы современной педиатрии</issue-title><fpage>56</fpage><lpage>61</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Яблокова Е., Горелов А., Чумакова О., Ратникова М., Сичинава И., 2006</copyright-statement><copyright-year>2006</copyright-year><copyright-holder xml:lang="ru">Яблокова Е., Горелов А., Чумакова О., Ратникова М., Сичинава И.</copyright-holder><copyright-holder xml:lang="en">Yablokova E., Gorelov A., Chumakova O., Ratnikova M., Sichinava I.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vsp.spr-journal.ru/jour/article/view/757">https://vsp.spr-journal.ru/jour/article/view/757</self-uri><abstract><p>Рост частоты воспалительных заболеваний кишечника (ВЗК) среди детей делает актуальным вопрос о раннем выявлении этой формы патологии и её осложнений, в том числе вторичного остеопороза. Цель исследования – изучить особенности минерализации костной ткани, нарушений физического и полового развития у детей, страдающих ВЗК. Обследовано 116 детей, в том числе 33 ребенка с ВЗК, 26 – с хроническим колитом, 29 – гастродуоденитом и 28 детей без патологии ЖКТ. Поведена оценка уровня минеральной плотности костной ткани (МПКТ), биохимических показателей костного метаболизма, а также физического и полового развития. Снижение МПКТ выявлено у 48,5% детей с ВЗК, у 23% — с хроническими колитами, у 31% — с хроническими гастритами и у 18% практически здоровых детей, причем у больных ВЗК оно было более выражено. Самые низкие показатели МПКТ были у девочек. Кальциево-фосфорный метаболизм не изменялся при остеопении, за исключением кальций-креатининового коэффициента. Таким образом, снижение минеральной плотности костной ткани часто наблюдается у детей с ВЗК, особенно у девочек пубертатного возраста. Это диктует необходимость включения денситометрии в стандартный план обследования детей с ВЗК. Целесообразен также мониторинг физического и полового развития детей. </p><p>Ключевые слова: дети, воспалительные заболевания кишечника, остеопороз.(Вопросы современной педиатрии. – 2006;5(4):56-61)</p></abstract><trans-abstract xml:lang="en"><p>The growth rate of inflammatory bowel diseases among children actualizes early detection of this pathology form and its aftera effects, including secondary osteoporosis. The research purpose is to study the characteristics of osseous tissue mineralization, disorder of physical growth and sexual maturity of children, suffering from inflammatory bowel diseases. The researchers have examined 116 children, including 33 children, suffering from inflammatory bowel diseases; 26 children, suffering from persistent colitis; 29 children, suffering from gasatroduodenitis; and 28 children with no GI tract pathologies. The study deals with estimate of level of mineral osseous tissue density, biochemical rates of osseous metabolism, as well as physical growth and sexual maturity. reduction of mineral osseous tissue density was found among 48,5% of children, suffering from inflammatory bowel diseases, 23% of children, suffering from persistent colitis, 31% of children, suffering from chronic gastritis and 18% of almost healthy children, at the same time, it was more apparent among children, suffering from inflammatory bowel diseases. The lowest rates of mineral osseous tissue density were among girls. Calcium phosphoric metabolism did not change apart from calcium creatinine coefficient, if osteopenia was observed. Thus, reduction of mineral osseous tissue density is often observed among children, suffering from inflammatory bowel diseases, especially among adolescent girls. Therefore, it conditions the necessity to include densimetry into the conventional examination plan for children, suffering from inflammatory bowel diseases. Authors also find it advisable to monitor physical growth and sexual maturity of children.</p><p>Key words: children, inflammatory bowel diseases, osteoporosis.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>воспалительные заболевания кишечника</kwd><kwd>остеопороз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>inflammatory bowel diseases</kwd><kwd>osteoporosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
