References

vsp

Вопросы современной педиатрии

Current Pediatrics

1682-55271682-5535

Издательство «ПедиатрЪ»

10.15690/vsp.v14i1.1260

vsp-79

Research Article

ОБЗОРЫ ЛИТЕРАТУРЫ

LITERATURE REVIEW

ПРЕБИОТИКИ В ДЕТСКИХ МОЛОЧНЫХ СМЕСЯХ

PREBIOTICS IN INFANT FORMULAS

Ванденплас

И.

Vandenplas

Yvan

профессор, UZ Brussel, Свободный университет Брюсселя Адрес: Ларбеклан 101, 1090, Брюссель, Бельгия, тел.: + 32-2-47-57-80

yvanvandenplas@uzbrussel.be

Захарова

И. Н.

Zakharova

I. N.

zakharova-rmapo@yandex.ru

Дмитриева

Ю. А.

Dmitrieva

Yu. A.

zakharova-rmapo@yandex.ru

Педиатрическая гастроэнтерология, UZ Brussel, Свободный университет Брюсселя, БельгияБельгияPaediatric Gastroenterology, UZ Brussels, Free University of Brussels, BelgiumBelgium

Российская медицинская академия последипломного образования, Москва, Российская ФедерацияРоссияRussian Medical Academy of Postgraduate Education, Moscow, Russian FederationRussian Federation

2015

14022015

141

Вопросы современной педиатрии

3137

2015

Ванденплас И., Захарова И.Н., Дмитриева Ю.А.

Vandenplas Y., Zakharova I.N., Dmitrieva Y.A.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://vsp.spr-journal.ru/jour/article/view/79

Микробиота желудочно-кишечного тракта отличается у младенцев, находящихся на грудном вскармливании и у детей, получающих стандартные молочные смеси. В то время как материнское молоко богато пребиотическими олигосахаридами, а также может содержать некоторые пробиотики, стандартная детская смесь не содержит ни того, ни другого. В рецептуре детских смесей используют различные пребиотические компоненты: галакто- и фруктоолигосахариды, полидекстрозу и их сочетания. Имеются свидетельства того, что добавление пребиотиков в детское питание позволяет приблизить микробиоту желудочно-кишечного тракта младенцев, получающих молочные смеси, к микробиоте детей, находящихся на грудном вскармливании. Пребиотики изменяют метаболическую активность микрофлоры кишечника (снижают pH стула, увеличивают содержание короткоцепочечных жирных кислот), оказывают бифидогенное воздействие и обеспечивают консистенцию стула и частоту дефекации, приближенную к этим параметрам у младенцев, находящихся на грудном вскармливании. Существуют немногочисленные свидетельства того, что такие изменения микробиоты желудочно-кишечного тракта могут оказывать определенное влияние на становление иммунной системы ребенка. Нежелательные явления при применении пребиотиков регистрируют чрезвычайно редко.

Microbiota of the gastrointestinal tract is different in breastfed infants and in children receiving standard infant formulas. While breast milk is rich in prebiotic oligosaccharides and can also contain some probiotics, standard infant formulas contain neither one thing nor the other. The formulation of an infant formula includes various prebiotic ingredients: galacto- and fructooligosaccharides, polydextrose and their combinations. There is evidence that the addition of prebiotics to baby food makes the microbiota of the gastrointestinal tract of infants receiving infant formulas more similar to the microbiota of breastfed children. Prebiotics alter the metabolic activity of the intestinal microflora (lower stool pH and increase the amount of short-chain fatty acids), have a bifidogenic effect and provide a stool consistency and bowel movement frequency that are similar to these parameters in breastfed infants. There is limited evidence that such changes in microbiota of the gastrointestinal tract may have some influence on the development of an infant's immune system. Adverse events are extremely rare in the application of prebiotics.

грудное вскармливаниемладенцыгалактоолигосахаридымолочная смесьпребиотики

breast feedinginfantsgalacto-oligosaccharidesmilk formulaprebiotics

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The authors declare that there are no conflicts of interest present.