<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vsp</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы современной педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Current Pediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-5527</issn><issn pub-type="epub">1682-5535</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">vsp-897</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБМЕН ОПЫТОМ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXCHANGE OF EXPERIENCE</subject></subj-group></article-categories><title-group><article-title>ЭФФЕКТИВНОСТЬ ПРИМЕНЕНИЯ СМЕСИ НА ОСНОВЕ ГИДРОЛИЗАТА КАЗЕИНА В ДИЕТОТЕРАПИИ ДЕТЕЙ С АЛЛЕРГИЕЙ К БЕЛКАМ КОРОВЬЕГО МОЛОКА</article-title><trans-title-group xml:lang="en"><trans-title>EFFECTIVENESS OF FORMULA BASED ON CASEIN HYDROLYSATE IN CHILDREN WITH ALLERGY TO PROTEINS OF COW’S MILK</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макарова</surname><given-names>И.В.</given-names></name><name name-style="western" xml:lang="en"><surname>Makarova</surname><given-names>I.V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тихонова</surname><given-names>В.С.</given-names></name><name name-style="western" xml:lang="en"><surname>Tikhonova</surname><given-names>V.S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>О.В. Жиглинская</surname><given-names>О.В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhiglinskaya</surname><given-names>O.V.</given-names></name></name-alternatives><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Медведева</surname><given-names>Е.А.</given-names></name><name name-style="western" xml:lang="en"><surname>Medvedeva</surname><given-names>E.A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аракелян</surname><given-names>Р.Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Arakelyan</surname><given-names>R.N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вовк</surname><given-names>Е.Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Vovk</surname><given-names>E.Yu.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Санкт-Петербургская государственная педиатрическая медицинская академия</institution><country>Россия</country></aff><aff xml:lang="en"><institution>St.-Petersburg State Pediatric Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Детская поликлиника №41, Санкт-Петербург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Children’s Out-patient Clinic № 41, St.-Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Детская поликлиника №46, Санкт-Петербург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Children’s Out-patient Clinic № 46, St.-Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ООО «Аника-Санкт-Петербург»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Public Corporation «Anika-Sankt-Petersburg»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>15</day><month>09</month><year>2015</year></pub-date><volume>9</volume><issue>3</issue><issue-title>Вопросы современной педиатрии</issue-title><fpage>97</fpage><lpage>101</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Макарова И., Тихонова В., О.В. Жиглинская О., Медведева Е., Аракелян Р., Вовк Е., 2010</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="ru">Макарова И., Тихонова В., О.В. Жиглинская О., Медведева Е., Аракелян Р., Вовк Е.</copyright-holder><copyright-holder xml:lang="en">Makarova I., Tikhonova V., Zhiglinskaya O., Medvedeva E., Arakelyan R., Vovk E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vsp.spr-journal.ru/jour/article/view/897">https://vsp.spr-journal.ru/jour/article/view/897</self-uri><abstract><p>Диетотерапия, наряду с лекарственным и наружным лечением, – один из компонентов комплексной терапии атопического дерматита (АтД) у детей. При тяжелых формах пищевой аллергии у детей первых лет жизни применяются специальные смеси на основе гидролизата казеина. Изучена клиническая эффективность такой смеси у 20 пациентов в возрасте 2–7 мес с непереносимостью белков коровьего и козьего молока. У всех детей с тяжелым течением болезни, включая кожные проявления АтД и гастроинтестинальные нарушения, удалось достичь ремиссии, уменьшить объем наружной терапии и отменить фармакотерапию. </p><p>Ключевые слова: дети, атопический дерматит, диетотерапия, гидролизат казеина, индекс SCORAD.(Вопросы современной педиатрии. – 2010;9(3):97-101)</p></abstract><trans-abstract xml:lang="en"><p>Dietotherapy along with medicinal and external treatment is one of components of complex treatment of atopic dermatitis (AD) in children. Severe forms of alimentary allergy are treated with special formulas based on casein hydrolisates. Clinical effectiveness of such formula was studied in 20 patients 2–7 months old intolerant to proteins of cow’s and goat’s milk. Treatment resulted in remission achievement, lessening of external therapy and cancellation of medicinal one in all children including those with cutaneous and gastrointestinal symptoms of AD.</p><p>Key words: children, atopic dermatitis, dietotherapy, casein hydrolysate, SCORAD.(Voprosy sovremennoi pediatrii — Current Pediatrics. – 2010;9(3):97-101)</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Атопический дерматит и инфекции кожи у детей: диагностика, лечение и профилактика. Научно-практическая программа. М. 2004. 36 с.</mixed-citation><mixed-citation xml:lang="en">Атопический дерматит и инфекции кожи у детей: диагностика, лечение и профилактика. Научно-практическая программа. М. 2004. 36 с.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Vandenplas Y., Brueton M., Dupont Ch. et al. Guidelines for the diagnosis and management of cows milk protein allergy in infants. Arch. Dis. Child. 2007; 92: 902–908.</mixed-citation><mixed-citation xml:lang="en">Vandenplas Y., Brueton M., Dupont Ch. et al. Guidelines for the diagnosis and management of cows milk protein allergy in infants. Arch. Dis. Child. 2007; 92: 902–908.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Jackson W. Food allergy. ILSI Europe. 2006. 136 p.</mixed-citation><mixed-citation xml:lang="en">Jackson W. Food allergy. ILSI Europe. 2006. 136 p.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Воронцов И.М., Маталыгина О.А. Болезни, связанные с пищевой сенсибилизацией у детей. М.: Медицина. 1986. 248 с.</mixed-citation><mixed-citation xml:lang="en">Воронцов И.М., Маталыгина О.А. Болезни, связанные с пищевой сенсибилизацией у детей. М.: Медицина. 1986. 248 с.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Host A., Kolezko B., Dreborg S. et al. Joint Statement of the European Society for Pediatric Allergology and Clinical Immunology (ESPACI) Committee on Hypoallergenic Formulas and the European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) Committee on Nutrition. Dietary products used in infants for treatment and prevention of food allergy. Arch. Dis. Child. 1999; 81: 80–84.</mixed-citation><mixed-citation xml:lang="en">Host A., Kolezko B., Dreborg S. et al. Joint Statement of the European Society for Pediatric Allergology and Clinical Immunology (ESPACI) Committee on Hypoallergenic Formulas and the European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) Committee on Nutrition. Dietary products used in infants for treatment and prevention of food allergy. Arch. Dis. Child. 1999; 81: 80–84.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">American Academy of Pediatrics/AAP. Committee on Nutrition. Hypoallergenic infant formulas. J. Pediatr. 2000; 196: 346–349.</mixed-citation><mixed-citation xml:lang="en">American Academy of Pediatrics/AAP. Committee on Nutrition. Hypoallergenic infant formulas. J. Pediatr. 2000; 196: 346–349.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Hannifin M., Rajka G. Diagnostic features of atopic dermatitis. Acta Dermatol. Venerol. (Stockholm). 1980; 114: 146–148.</mixed-citation><mixed-citation xml:lang="en">Hannifin M., Rajka G. Diagnostic features of atopic dermatitis. Acta Dermatol. Venerol. (Stockholm). 1980; 114: 146–148.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Коростовцев Д.С., Макарова И.В., Ревякина В.А., Горланов И.А. Индекс SCORAD – объективный и стандартизированный метод оценки поражения кожи при атопическом дерматите. Аллергология. 2000; 3: 39–43.</mixed-citation><mixed-citation xml:lang="en">Коростовцев Д.С., Макарова И.В., Ревякина В.А., Горланов И.А. Индекс SCORAD – объективный и стандартизированный метод оценки поражения кожи при атопическом дерматите. Аллергология. 2000; 3: 39–43.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Чебуркин А.А., Страхова М.С. Использование гидролизатов белка в питании детей с аллергическими реакциями на коровье молоко. Детский доктор. 2001; 3: 33–38.</mixed-citation><mixed-citation xml:lang="en">Чебуркин А.А., Страхова М.С. Использование гидролизатов белка в питании детей с аллергическими реакциями на коровье молоко. Детский доктор. 2001; 3: 33–38.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
