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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vsp</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы современной педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Current Pediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-5527</issn><issn pub-type="epub">1682-5535</issn><publisher><publisher-name>Издательство «ПедиатрЪ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15690/vsp.v13i6.1195</article-id><article-id custom-type="elpub" pub-id-type="custom">vsp-95</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERATURE REVIEW</subject></subj-group></article-categories><title-group><article-title>КАНАКИНУМАБ В ЛЕЧЕНИИ РЕВМАТИЧЕСКИХ БОЛЕЗНЕЙ У ДЕТЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>CANAKINUMAB IN THE TREATMENT OF RHEUMATIC DISEASES IN CHILDREN</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеева</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseeva</surname><given-names>Ye. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексеева Екатерина Иосифовна, доктор медицинских наук, профессор, заведующая ревматологическим отделением Научного центра здоровья детей, декан педиатрического факультета Первого МГМУ им. И.М. Сеченова</p></bio><email xlink:type="simple">alekatya@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Денисова</surname><given-names>Р. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Denisova</surname><given-names>R. V.</given-names></name></name-alternatives><email xlink:type="simple">neonatepearl@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научный центр здоровья детей, Москва;, &#13;
Первый Московский государственный медицинский университет им. И.М. Сеченова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Centre of Children Health, Moscow;&#13;
Sechenov First Moscow State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научный центр здоровья детей, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Centre of Children Health, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>10</day><month>12</month><year>2014</year></pub-date><volume>13</volume><issue>6</issue><issue-title>Вопросы современной педиатрии</issue-title><fpage>9</fpage><lpage>14</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Алексеева Е.И., Денисова Р.В., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Алексеева Е.И., Денисова Р.В.</copyright-holder><copyright-holder xml:lang="en">Alekseeva Y.I., Denisova R.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vsp.spr-journal.ru/jour/article/view/95">https://vsp.spr-journal.ru/jour/article/view/95</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>канакинумаб</kwd><kwd>системный ювенильный идиопатический артрит</kwd><kwd>криопиринассоциированные периодические синдромы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>kanakinumab</kwd><kwd>juvenile idiopathic arthritis</kwd><kwd>cryopyrin-associated periodic syndromes</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">(Вопросы современной педиатрии. 2014; 13 (6): 9–14)</mixed-citation><mixed-citation xml:lang="en">(Вопросы современной педиатрии. 2014; 13 (6): 9–14)</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Dinarello C. 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