Breast Milk Protective Factors Modelling: Nutritional Programming of Child’s Health
https://doi.org/10.15690/vsp.v20i6.2355
Abstract
This review covers modern possibilities of modeling breast milk unique properties to produce infant milk formulas. The main approach of such modelling is to advance the protein composition in the formula to the spectrum of breast milk proteins, primarily α-lactalbumin. This protein has multi-directional protective properties; the organism synthesizes the antibacterial and immunomodulating peptide complex HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells, complex of α-lactalbumin and oleic acid) on its basis. The amino acid composition of α-lactalbumin provides mild neuroprotective effect due to sufficient level of tryptophan. Non-protein components of the produced formulas (carbohydrate and fat included) enhance their protective qualities and ensure the prevention of delayed health disorders. This review provides information about the innovative baby food product containing ?-lactalbumin and other bioactive components like those in breast milk.
Supporting agencies: The article was funded by Biofoodnutrition.
About the Authors
Irina A. Belyaeva
Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”;
Pirogov Russian National Research Medical University;
Morozovskaya Children’s City Hospital
Russian Federation
Disclosure of interest:
Russian Federation
Moscow
Disclosure of interest:
lecturing for pharmaceutical companies “Progress”, “Medela”, “Akrikhin”, Nestle, HiPP Russ LLC
Elena P. Bombardirova
Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”
Russian Federation
Disclosure of interest:
Russian Federation
Moscow
Disclosure of interest:
The other contributors confirmed the absence of a reportable conflict of interests
Tatiana V. Turti
Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”;
Pirogov Russian National Research Medical University;
Research Institute for Healthcare Organization and Medical Management
Russian Federation
Disclosure of interest:
Russian Federation
Moscow
Disclosure of interest:
lecturing for pharmaceutical companies “Progress”, “Akrikhin”.
Evgeniia A. Prikhodko
Morozovskaya Children’s City Hospital
Russian Federation
Disclosure of interest:
Russian Federation
Moscow
Disclosure of interest:
The other contributors confirmed the absence of a reportable conflict of interests
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For citations:
Belyaeva I.A., Bombardirova E.P., Turti T.V., Prikhodko E.A. Breast Milk Protective Factors Modelling: Nutritional Programming of Child’s Health. Current Pediatrics. 2021;20(6):492-498. (In Russ.) https://doi.org/10.15690/vsp.v20i6.2355
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