Состав микробиома кожи и ключевые аспекты его барьерной функции

Кожа является крупнейшим органом организма человека, который образует защитный барьер между внутренней и внешней средой. Повреждение кожного барьера несет потенциальный риск развития дисбаланса гомеостаза кожного покрова, воспаления и бактериальной инфекции. Микробиом играет решающую роль в поддержании нормального функционирования кожи: контроль патогенного разнообразия микроорганизмов, стимуляция иммунных клеток и модулирование развития хронических дерматозов. Существуют различные механизмы восстановления барьерной функции кожи, которые связаны с активностью микроорганизмов, что является важнейшей задачей, входящей в общую концепцию лечения атопического дерматита. Одним из таких механизмов является колонизация поверхности кожи комменсалами, где существенную роль отводят новым средствам дерматологической косметики. Нормализация микробиома пораженных участков кожи с помощью косметических средств ухода может значимо влиять на результат восстановления кожного барьера.

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