RISK FACTORS FOR THE EARLY NEONATAL MORTALITY IN NEWBORNS WITH VERY LOW AND EXTREMELY LOW BIRTH WEIGHT
https://doi.org/10.15690/vsp.v13i6.1199
Abstract
Objective: Our aim was to assess the association of perinatal factors with the early neonatal mortality in newborns with very low (VLBW) and extremely low birth weight (ELBW).Methods: The statistical data was carried out, that is analysis of 17 perinatal factors of 28 newborns with an ELBW with gestation of 23–27 weeks and 18 newborns with a VLBW with gestation of 28–32 weeks, who died in the first 7 days of life. The comparison group consisted of 25 newborns with an ELBW and 56 children with a VLBW with gestation of 25–27 and 28–32 weeks, respectively, who survived the early neonatal period. The association of risk factors with the early neonatal mortality was assessed by means of a multiple-factor logistic regression analysis. A critical p error level was set equal to 0.05. Results: In newborns with a VLBW the increased risk of the early neonatal mortality depended on a gestation term (OR 4.40, 95% CI 1.56–11.71; р = 0.002) and emergency Caesarean section (OR 7.48, 95% CI 1.28–43.74; р = 0.008). A vaginal birth increased the survival chance (OR 0.12, 95% CI 0.01–0.86; р = 0.032). Newborns with an ELBW had the following factors of the increased risk of the early neonatal mortality: gestational age (OR 2.86, 95% CI 1.06–7.73; р = 0.038), Apgar score at the 5th minute (OR 1.91, 95% CI 0.99–3.69; р = 0.050) and presence of chorioamnionitis (OR 5.45, 95% CI 1.0–29.53; p = 0.048). An elective Caesarean section increased the survival chance (OR 0.02, 95% CI 0.001–0.44; p = 0.048). Conclusion: Summarizing the obtained data, we can conclude that besides a gestational age the risk of early neonatal mortality in newborns with a VLBW may be increased due to the emergency Caesarean section, with an ELBW — due to a low Apgar score at the 5th minute and the presence of mother's chorioamnionitis. A vaginal birth in newborns with a VLBW and an elective Caesarean section in children with an ELBW increase survival chances.
About the Authors
О. V. Lebedeva
Astrakhan State Medical Academy
Russian Federation
Russian Federation
Т. А. Chikina
Clinical Maternity Hospital, Astrakhan
Russian Federation
Russian Federation
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Review
For citations:
Lebedeva О.V., Chikina Т.А. RISK FACTORS FOR THE EARLY NEONATAL MORTALITY IN NEWBORNS WITH VERY LOW AND EXTREMELY LOW BIRTH WEIGHT. Current Pediatrics. 2014;13(6):35-39. (In Russ.) https://doi.org/10.15690/vsp.v13i6.1199
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