Preview

Current Pediatrics

Advanced search

CLINICAL EFFECTIVENESS OF NONSTEROID ANTI-INFLAMMATORY MEDICATIONS IN TREATMENT OF ENT-DISEASES IN CHILDREN

Abstract

This trial included 97 children with acute tonsillopharyngitis (angina), acute pharyngitis, laryngitis, otitis media. Ibubrofen suspension (Nurofen for Children) was administrated in standard dose. Good and excellent analgetic and antipyretic result was registered in 75% of patients after 1 day, and satisfactory – in 25% of children. 44 children with different diseases of throat were treated with flurbiprofen as symptomatic anesthetic medication combined with other ones. Pain in throat and deglutitive problems were lessened after 2-3 hours after 1 administration of medication, and further reduction of symptoms was registered every 3 hours. Pain in throat was stopped in 38 children after 3 days of treatment. Thus, ibuprofen suspension and resorption tablets with flurbiprofen provide significant anesthetic effect in children, and they can be used in practice of children’s ENT specialist.
Key words: children, ENT diseases, nonsteroid anti-inflammatory medications.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(1):81-84)

About the Authors

M.M. Sergeev
Kuban’ State Medical University, Krasnodar
Russian Federation


S.L. Kovalenko
Kuban’ State Medical University, Krasnodar
Russian Federation


References

1. Rabinowitz H.K. Upper respiratory tract infections. Prim. Care. 1990; 17: 793–809

2. Burke P. Sore throat. Practitioner. 1993; 237: 854–856.

3. Muhrer J.C. Diagnostic considerations in the evaluation and treatment of sore throat. Nurse Practitioner. 1991; 16: 33–45.

4. Карпов О.И., Зайцев А.А. Нестероидные противовоспалительные препараты аспекты безопасности длительного применения. Новые Санкт-Петербургские врачебные новости. 2001; 4: 79–82.

5. Arcimovicz M., Samolinski B., Gotlib T. et al. Nimesulide – the selective COX-2 inhibitor in the treatment of ENT diseases. Otolaryngol. P. 2002; 56: 501–507.

6. Fang J.Y., Hwang T.L., Fang L. et al. In vitro and in vivo evaluations of the efficacy and safety of skin permeation enhancers using flurbiprofen as a model drug. Int. J. Pharm. 2003; 255 (1-2): 153–166.

7. Battist N. The evaluation of the analgesic and anti-inflammatory effects of flurbiprofen mouth wash and 100 mg tablets in oral medicine. Miner. Stomatol. 1994; 43 (4): 141–144.


Review

For citations:


Sergeev M., Kovalenko S. CLINICAL EFFECTIVENESS OF NONSTEROID ANTI-INFLAMMATORY MEDICATIONS IN TREATMENT OF ENT-DISEASES IN CHILDREN. Current Pediatrics. 2009;8(1):81-84.

Views: 828


ISSN 1682-5527 (Print)
ISSN 1682-5535 (Online)