BIOCENOSIS SAVING EFFICIENCY OF NIFUROXAZIDE DURING ACUTE ENTERIC INFECTIONS AMONG CHILDREN

A.V. Gorelov; D.V. Usenko; M.D. Ardatskaya

BIOCENOSIS SAVING EFFICIENCY OF NIFUROXAZIDE DURING ACUTE ENTERIC INFECTIONS AMONG CHILDREN

A.V. Gorelov, D.V. Usenko, M.D. Ardatskaya

Abstract

The authors made a comparative efficiency evaluation of the nifuroxazide (enterofuryl) and other nalidixic acid based medications in treatment of the acute enteric infections among children. The authors determined that though they had the equal clinical efficiency (comparable terms for the couping of the disease symptoms) enterofuryl based therapy was accompanied by the activity reduction of the opportunistic pathogenic microflora (in particular, proteolytic cultures) and balance normalization of the aerobic-anaerobic microorganism populations. The application of the nalidixic acid quite on the contrary intensified the metabolic disorders among some of the patients.
Key words: acute enteric infections, children, treatment, nifuroxazide, short-chain fatty acids.

About the Authors

A.V. Gorelov

Central Research Institute of Epidemiology, Russian Federal Consumer Rights Protection and Human Health Control Service, Moscow
Russian Federation

D.V. Usenko

Central Research Institute of Epidemiology, Russian Federal Consumer Rights Protection and Human Health Control Service, Moscow
Russian Federation

M.D. Ardatskaya

Medical Center of the President's Executive Secretariat, Moscow
Russian Federation

References

1. Горелов А.В., Милютина Л.Н., Усенко Д.В. Клинические рекомендации по диагностике и лечению острых кишечных инфекций у детей. Пособие для врачей. М. 2006. 109 с.

2. Малеев В.В. Инфекционные болезни в России: проблемы и пути их решения. Инфекционные болезни. 2004; 2 (1): 7–11.

3. Чернуха М.Ю. Антибиотикорезистентность и возможное происхождение штаммов S. aureus и Klebssiella, выделенных от детей с дисбактериозом кишечника. ЖМЭИ. 2005; 5: 66–70.

4. Кондракова О.А. Комплексная оценка микроэкологических и функциональных нарушений толстого кишечника для обеспечения этиотропной терапии. Пособие для врачей. М. 2003. 54 с.

5. Феклисова Л.В. Оптимизация результатов лечения детей, больных острыми кишечными инфекциями, при использовании отечественных биологических микробных препаратов. Вестник РАМН. 2005; 12: 17–24.

Review

For citations:

Gorelov A., Usenko D., Ardatskaya M. BIOCENOSIS SAVING EFFICIENCY OF NIFUROXAZIDE DURING ACUTE ENTERIC INFECTIONS AMONG CHILDREN. Current Pediatrics. 2007;6(2):110-114.

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International.

ISSN 1682-5527 (Print)
ISSN 1682-5535 (Online)

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Current Pediatrics

BIOCENOSIS SAVING EFFICIENCY OF NIFUROXAZIDE DURING ACUTE ENTERIC INFECTIONS AMONG CHILDREN

Abstract

About the Authors

References

Review

For citations:

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