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INNATE IMMUNITY: MECHANISMS OF REALIZATION AND PATHOLOGICAL SYNDROMES. PART II

Abstract

The role and mechanisms of realization of biomechanical, physical, chemical and biological factors of system of non-specific defense of organism are discussed in this article. Authors characterize the main cell and humoral factors of this system; analyze etiology, pathogenesis and main signs of syndromes of insufficiency of immunosurveillance of organism, developing as a result of disorders of inborn immunity mechanisms.
Key words: biomechanical and physical, chemical factors of defense, natural killers, cytolysis mechanisms, syndrome of inborn immunity insufficiency.
(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(2):59-67)

About the Authors

P.F. Litvitsky
I.M. Sechenov Moscow Medical Academy
Russian Federation


T.G. Sinel’nikova
I.M. Sechenov Moscow Medical Academy
Russian Federation


References

1. Кокряков В.Н. Очерки о врожденном иммунитете. СПб.: Наука. 2006. 261 с.

2. Литвицкий П.Ф. Патофизиология. М.: ГЭОТАР–Медиа. 2007. Т. 1. С. 212–237.

3. Gould B. Pathophysiology for the Health Profession. 3 ed. Elsevier. 2006. Р. 46–53.

4. Vivier E., Colonna M. Immunology of Natural Killer Cell Receptors. Springer. 2006. 350 р.


Review

For citations:


Litvitsky P., Sinel’nikova T. INNATE IMMUNITY: MECHANISMS OF REALIZATION AND PATHOLOGICAL SYNDROMES. PART II. Current Pediatrics. 2009;8(2):59-67.

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ISSN 1682-5527 (Print)
ISSN 1682-5535 (Online)