Preview

Current Pediatrics

Advanced search

NUCLEOTIDES IN INFANT FEEDING

Abstract

The article reviews the application of nucleotides-metabolites, playing a key role in many biological processes, for the infant feeding. The researcher provides the date on the nucleotides in the women's milk according to the lactation stages. She also analyzes the foreign experience in feeding newborns with nucleotides-containing milk formulas. The article gives a comparison of nucleotides in the adapted formulas represented in the domestic market of the given products.
Key words: children, feeding, nucleotides.

About the Author

L.G. Mamonova
Scientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow
Russian Federation


References

1. Ohyanagi H., Nishimatsu S., Kanbara Y. et al. Effects of nucleosides and a nucleotide on DNA and RNA syntheses by the salvage and de novo pathway in primary monolayer cultures of hepatocytes and hepatoma cells. J. Parenter Enteral Nutr. 1989; 13 (1): 51–58.

2. Carver J.D. Dietary nucleotides and hepatic system effects. J. Nutr. 1994; 124: 144–148.

3. Carver J.D., Walker W.A. The role of nucleotides in human nutrition. S. Nutr. Biochem. 1995; 6: 58–72.

4. Cosgrove M. Perinatal and infant nutrition. Nucleotides Nutr. 1998; 14: 748–751.

5. Quan R., Uauy R. Nucleotides and gastrointestinal development. Sem. Pediatr. Gastroenterol. Nutr. 1991; 2: 3–11.

6. Uauy R., Quan R., Gil A. Role of nucleotides in intestinal development and repair: implications for infant formula. J. Nutr. 1994; 124: 1436–1441.

7. Carlson S.E. Human milk nonprotein nitrogen: occurrence and possible function. Adv. Pediatr. 1985; 32: 43–70.

8. Barness L.A. Dietary sources of nucleotides from breast milk to weaning. J. Nutr. 1994; 124: 128–130.

9. Leach J.L., Baxter J.H., Molitor B.E. et al. Total potentially available nucleosides of human milk by stage of lactation. Am. J. Clin. Nutr. 1995; 61 (6): 1224–1230.

10. Goldman A.S., Goldblum R.M. Immunologic systems in human milk: characteristics and effects. In Lebenthoul E. Textbook of Gastroenterology and Nutrition in Infancy (second edition). NY: Raven Press. 1989. P. 135–142.

11. Gil A., Sanchez-Medina F. Acid soluble nucleotides of cow's, goat's and sheep's milks, at different stages of lactation. J. Dairy Res. 1981; 48: 35–44.

12. Carver J.D., Pimentel B., Cox W.I. et al. Dietary nucleotide effects upon immune function in infants. Pediatrics. 1991; 88 (2): 359–363.

13. Iyonouchi H. Nucleotide actions on humoral immune response. J. Nutr. 1994; 124: 138–143.

14. Kulkarni A.D., Rudolph F.B., Van Buren C.T. The role of dietary sources of nucleotides in immune function: a review. J. Nutr. 1994; 124 (Suppl. 8): 1442–1446.

15. Carver J.D. Dietary nucleotides: effects on the immune and gastrointestinal systems. Acta Paediatr. Suppl. 1999; 88 (430): 83–88.

16. MartinezBAugustin O., Boza J.J., Navarro J. et al. Dietary nucleotides may influence the humoral immunity in immunocompromised children. Nutrition. 1997; 13 (5): 465–469.

17. Pickering L., Granoff D., Erickson J.R. et al. Modulation of the immune system by human milk and infant formula, containing nucleotides. Pediatrics. 1998; 101: 242–249.

18. Uauy R., Stringel G., Thomas R. et al. Effect of dietary nucleosiden on growth and maturation of the developing gut in the rat. J. Pediatr. Gastroenterol. Nutr. 1990; 10: 497–503.

19. Sanderson I.R., He Y. Nucleotide uptake and metabolism by intestinal epithelial cells. J. Nutr. 1994; 124: 131–137.

20. Brunser O., Espinoza J., Araya M. et al. Effect of dietary nucleotide supplementation on diarrhoeal disease in infants. Acta Paediatr. 1994; 83 (2): 188–191.

21. Uauy R. Nonimmune sistem responses to dietary nucleotides. J. Nutr. 1994; 124: 157–159.

22. Gil A., Pita M., Martinez A. et al. Effect of dietary nucleotides on the plasma fatty acids in at term neonates. Hum. Nutr. Clin Nutr. 1986; 40 (3): 185–195.

23. Balmer S.E., Hanvey L.S., Wharfon B.A. Diet and fecal flora in the newborn: nucleotides. Arch. Dis. Child. Fetal Neonataled. 1994; 70 (2): 137–140.

24. Chu S.W. Nucleotides: biochemistry and metabolism. Sem. Pediatr. Gast. Nutr. 1991; 2: 3–11.

25. Cosgrove M., Davies D.P., Jenkins H.R. Nucleotide supplementation and the growth of term small for gestational age infants. Arch. Dis. Child Fetal. Neonatal. Ed. 1996; 74 (2): 122–125.

26. Gil A., Corral E. Effects of the addition of nucleotides to an adapted milk formula on the microbial pattern of faces in at term newborn infants. J. Clin. Nutr. Gastroenterol. 1986; 1: 127–132.

27. DeLucchi C., Pita M.L., Faus M.J. et al. Effects of dietary nucleotides on the fatty acid composition of erythrocyte membrane lipids in term infants. J. Pediatr. Gastroenterol. Nutr. 1987; 6 (4): 568–574.

28. Коровина Н.А., Захарова И.Н., Малова Н.Е., Лыкина Е.В. Роль нуклеотидов в питании детей первого года жизни. Педиатрия. 2004; 5: 65–68.

29. Грибакин С.Г., Казакова С.Н., Андреева А.В. Значение нуклеотидов в питании детей грудного возраста. Вопросы практической педиатрии. 2005; 3 (2): 8–11.


Review

For citations:


Mamonova L. NUCLEOTIDES IN INFANT FEEDING. Current Pediatrics. 2007;6(6):113-116.

Views: 622


ISSN 1682-5527 (Print)
ISSN 1682-5535 (Online)