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SPONTANEOUS CARPAL TARSAL OSTEOLYSIS IN CHILDREN'S RHEUMATOLOGIST PRACTICE

Abstract

The case report of spontaneous carpalbtarsal osteolysis in 11byearbold boy is presented in this article. The attention draw to the rarity of this disease, the literature data of spontaneous osteolysis was given. The features of clinical presentation were described, and need of differential diagnosis with juvenile rheumatoid arthritis was proved.
Key words: spontaneous carpal tarsal osteolysis, differential diagnosis.

About the Authors

E.S. Zholobova
I.M. Sechenov Moscow Medical Academy
Russian Federation


V.N. Bobyleva
I.M. Sechenov Moscow Medical Academy
Russian Federation


G.V. Mikhaleva
I.M. Sechenov Moscow Medical Academy
Russian Federation


References

1. Eisenstein D.M., Poznanski A.K.,Pachman L.M. Torg osteolysis syndrom. Am. J. Med. Genet. 1998; 16 (80): 207–212.

2. Al Aqeel A., Al Sewairi W., Edress B. et al. Inherited multicentric osteolysis with arthritis: a variant resembling Torg syndrome in a Saudi family. Am. J. Med. Genet. 2000; 3 (93): 11–18.

3. Zankl A., Pachman L., Poznanski A. et al. Torg syndrome is caused by inactivating mutations in MMP2 and is allelic to NAO and Winchester syndrome. J. Bone Miner Res. 2007; 22 (2): 329–333.

4. Rouzier C., Vanatka R., Bannwarth S. et al. A novel homozygous MMP2 mutation in a family with Winchester syndrome. Clin. Genet. 2006; 69 (3): 271–276.

5. Singh J.A., Williams C.B., McAlister W.H. Talo–patella scaphoid osteolysis, synovitis, and short fourth metacarpals in sisters: a new syndrome? Am. J. Med. Genet. A. 2003; 30 (121): 118-125.

6. Faber M.R., Verlaak R., Fiselier T.J. et. al. Inherited multicentric osteolysis with carpal-tarsal localization, mimicking juvenile idiopathic arthritis. Eur. J. Pediatr. 2004; 163 (10): 612-618.


Review

For citations:


Zholobova E., Bobyleva V., Mikhaleva G. SPONTANEOUS CARPAL TARSAL OSTEOLYSIS IN CHILDREN'S RHEUMATOLOGIST PRACTICE. Current Pediatrics. 2008;7(3):113-116.

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ISSN 1682-5527 (Print)
ISSN 1682-5535 (Online)