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EXPERIENCE OF TREATMENT OF JUVENILE POLYARTHRITIS WITH EYES LESION WITH ADALIMUMAB

Abstract

A case report of early debut and severe course of juvenile poly arthritis with eyes lesion refractory to classic immuno suppressive agents is presented in this article. Successful application of biological agent adalimumab is described: acute inflammatory alterations in affected joints were stopped by 49 the week. Range of motions in affected joints was recovered. The remission of veitis, normalization of indicators of disease activity (ESR, concentration of creactive protein in blood plasma) was registered by 89 th week.
Key words: children, juvenile rheumatoid arthritis, rheumatoid uveitis, adalimumab.

About the Authors

A.O. Lisitsin
Scientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow
Russian Federation


E.I. Alexeeva
Scientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow
Russian Federation


T.M. Bzarova
Scientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow
Russian Federation


S.I. Valieva
Scientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow
Russian Federation


A.M. Chomakhidze
Scientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow
Russian Federation


K.B. Isaeva
Scientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow
Russian Federation


E.G. Chistyakova
Scientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow
Russian Federation


R.V. Denisova
Scientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow
Russian Federation


E.Yu. Gudkova
Scientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow
Russian Federation


N.A. Karagulyan
Scientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow
Russian Federation


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Review

For citations:


Lisitsin A., Alexeeva E., Bzarova T., Valieva S., Chomakhidze A., Isaeva K., Chistyakova E., Denisova R., Gudkova E., Karagulyan N. EXPERIENCE OF TREATMENT OF JUVENILE POLYARTHRITIS WITH EYES LESION WITH ADALIMUMAB. Current Pediatrics. 2008;7(5):115-120.

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ISSN 1682-5527 (Print)
ISSN 1682-5535 (Online)