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EXPERIENCE OF FIFTEEN YEAR USE OF CYCLOSPORIN IN PAEDIATRIE RHEUMATOLOGY

Abstract

A data of fifteen year experience of use of cyclosporin in treatment of systemic type of juvenile rheumatoid arthritis is presented in this article. Ciclosporin is high effective medication in mono therapy and combined with methotrexate. Cyclosporine in dose 3,5–4,5 mg/kg of bogy mass has no significant adverse events as in mono therapy, as in combination with methotrexate in moderate and high dose. Proper data of treatment of severe systemic type of rheumatoid arthritis in more then 100 children is presented.
Key words: children, juvenile rheumatoid arthritis, cyclosporin, treatment.

About the Authors

E.I. Alexeeva
Scientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow
Russian Federation


I.E. Shakhbazyan
Scientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow
Russian Federation


S.I. Valieva
Scientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow
Russian Federation


T.M. Bzarova
Scientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow
Russian Federation


K.B. Isaeva
Scientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow
Russian Federation


A.M. Chomakhidze
Scientific Center of Children's Health, Russian Academy of Medical Sciences, Moscow
Russian Federation


E.Yu. Afonina
I.M. Sechenov Moscow Medical Academy
Russian Federation


O.S. Rozvadovskaya
I.M. Sechenov Moscow Medical Academy
Russian Federation



V.Ya. El'yashevich
I.M. Sechenov Moscow Medical Academy
Russian Federation


D.V. Apaeva
I.M. Sechenov Moscow Medical Academy
Russian Federation


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Review

For citations:


Alexeeva E., Shakhbazyan I., Valieva S., Bzarova T., Isaeva K., Chomakhidze A., Afonina E., Rozvadovskaya O., El'yashevich V., Apaeva D. EXPERIENCE OF FIFTEEN YEAR USE OF CYCLOSPORIN IN PAEDIATRIE RHEUMATOLOGY. Current Pediatrics. 2008;7(6):104-117.

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