EARLY CHILDHOOD CARIES: CAN YOU PREVENT IT?
https://doi.org/10.15690/vsp.v13i5.1153
Abstract
The probability of the caries development largely depends on the oral microflora imbalance. This imbalance can be corrected with probiotics. The article analyzes the results of studies on the use of adapted milk formulas with probiotics to prevent caries in early childhood. It shows that the use of adapted formulas with probiotics is accompanied by a decrease in the frequency of releasing cariogenic streptococci and actinomycetes with a simultaneous increase in the frequency of detecting bacterial antagonists of the cariogenic flora, normalization of sIgA concentration in saliva, and decrease in the severity of the caries process. The survey results will contribute to the development of effective approaches to prevention of dental caries in children.
About the Authors
K. B. Miloserdova
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation
Russian Federation
О. V. Zaytseva
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
L. P. Kisel’nikova
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation
Russian Federation
V. N. Tsarev
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation
Russian Federation
References
1. Кисельникова Л. П., Вагеманс Н. В. Современные возможности профилактики кариеса зубов у детей раннего возраста. Педиатрия. 2010; 89 (5): 130–136.
2. Леонтьев В. К., Кисельникова Л. П. Детская терапевтическая сто ма тология. Национальное руководство. М.: ГЭОТАР-Медиа, 2010, 890 с.
3. Lundell A. G., Anderson K., Josefsson E. Soluble CD14 and CD83 from human neonatal antigen-presenting cells are inducible by commensal bacteria and suppress human neonatal Th2 differentiation. Infect. & Immunity. 2007; 75: 4097–4104.
4. Saavedra Use of Probiotics in Pediatrics: Rationale, Mechanisms of Action, and Practical application. Saavedra. Nutr. Clin. Pract. 2007; 22: 351–365.
5. Guemonde M., Laitinen K., Salminen S. Breast milk: a source of bifidobacteria for infant gut development and maturation? Neonatology. 2007; 92: 64–66.
6. Yli-Knuuttila, Snall J., Kari K. Colonization of Lactobacillus rhamnosus GG in the oral cavity. Oral Microbiol. Immunol. 2006; 21: 129–131.
7. Guideline on perinatal oral health care. NGC: 007120. Am. Acad. Pediatr. Dentistry. Pediatr Dent. 2008–2009; 30 (Suppl. 7): 163–169.
8. Hinds K., Gregory J. National Diet and Nutrition Survey: children aged 1.5–4.5 years. Vol. 2. Report of the dental survey. London: Her Majesty’s Stationery Office. 1995.
9. Бондаренко В. М. Молекулярно-клеточные механизмы терапевтического действия пробиотических препаратов. Фарматека. 2010; 2: 26–32.
10. Leeber S., Vanderleydes G., De Keersmaecker S. C. Genes and molecules of lactobacillus supporting probiotic action. Microbiol. Mol. Biol Rev. 2008; 72: 728–764.
11. Нетребенко О. К. Обзор новых статей и материалов по механизмам действия и роли пробиотиков у детей (2007–2008). Педиатрия и детская хирургия. 2009; 3 (57): 68–72.
12. Guidelines for Evalution of Probiotics in Food. Report of a Joint FAO/WHO working group on guideliness for the evaluation of probiotics in food. London — Ontario. 2002. 11 p.
13. Парфенов А. И., Бондаренко В. М. Что нам дал вековой опыт познания симбионтной кишечной микрофлоры. Архив патологии. 2012; 2: 21–25.
14. Терехова Т. Н., Шаковец Н. В., Ковальчук Н. В. Применение пробиотического напитка с целью профилактики кариеса зубов у дошкольников. Клиническая стоматология. 2013; 3: 4–8.
15. Mancini J., Garbonara O. O., Heremans J. F. Immunochemical diagnostitation of antigens by single radial immunodiffusion. J. Immunochemistry. 1965; 2 (3): 235–239.
Review
For citations:
Miloserdova K.B., Zaytseva О.V., Kisel’nikova L.P., Tsarev V.N. EARLY CHILDHOOD CARIES: CAN YOU PREVENT IT? Current Pediatrics. 2014;13(5):76-79. (In Russ.) https://doi.org/10.15690/vsp.v13i5.1153
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