Peculiarities of the Course and Prevention of Diaper Dermatitis in Newborns and Infants
https://doi.org/10.15690/vsp.v14i6.1481
Abstract
The article presents current data on the peculiarities of the etiology and pathogenesis of diaper dermatitis in newborns and infants. The role of enzymes in the gastrointestinal tract, of bacterial and fungal agents in its development is showed. The data on peculiarities of the differential diagnosis of skin diseases involving the anogenital area is given. The peculiarities of psoriasis manifestation with typical inversion of skin pathological process in infancy are noted. The results of clinical studies on the efficacy and safety of dexpanthenol in the treatment of diaper dermatitis are highlighted, the basic principles of its prevention are announced.
About the Authors
N. N. Murashkin
Scientific Center of Children’s Health, Moscow, Russian Federation
Russian Federation
Russian Federation
A. I. Materikin
Scientific Center of Children’s Health, Moscow, Russian Federation
Russian Federation
Russian Federation
R. V. Yepishev
Scientific Center of Children’s Health, Moscow, Russian Federation
Russian Federation
Russian Federation
E. T. Ambarchyan
Scientific Center of Children’s Health, Moscow, Russian Federation
Russian Federation
Russian Federation
References
1. Berg RW. Etiologie and pathophysiology of nappy dermatitis. Adv Dermatol. 1998;3:75–98.
2. Emdadi M, Bazmamoun H. The Frequency of Diaper Dermatitis in 0–2 years old children at nursing homes in Hamadan on 2000– 2001. Sci J Hamadan Univ Med Sci. 2004:44–45.
3. Philipp R, Hughes A, Golding J. Getting to the bottom of nappy rash. ALSPAC Survey Team. Avon Longitudinal Study of Pregnancy and Childhood. Br J Gen Pract. 1997;47(421):493–497.
4. Sryzdy S, Janghorbani M, Ghadi Pasha N. Diaper dermatitis prevalence and risk factors in children under 2 years of kindergarten in 1373 Kerman. Iran J Dermatol. 1997;1:24–28.
5. Wananukul S, Limpongsanuruk W, Singalavanija S, Wisuthsarewong W. Comparison of dexpanthenol and zinc oxide ointment with ointment base in the treatment of irritant diaper dermatitis from diarrhea: a multicenter study. J Med Assoc Thai. 2006;89(10):1654–1658.
6. Teillac-Hammel D. La peau de l`enfant estelle differente? Nouv Dermatol. 1994;13:398–402.
7. Maes DH. Main finished products: Moisturizing and cleansing creams. Textbook of Neonatal Dermatology. New York. 2001. Р. 19–32.
8. Fox C, Nelson D, Wareham J. The Timing of Skin Acdification in very low Birth Weight Infants. J Perinatol. 1998;18(4):272–275.
9. Manchini A. Structure and Function of Newborn Skin. Textbook of Neonatal Dermatology. New York. 2001. Р. 18–32.
10. Wolf R, Wolf D, Tuzun B, Tuzun Y. Diaper dermatitis. Clin Dermatol. 2000;18:657–660.
11. Paige DG, Gennery AR, Cant AJ. The Neonate. In: Rook’s Textbook of Dermatology. Eds. Burns T, Breathnach S, Cox N, Griffiths. 8th Ed. Oxford: Blackwell Publ. Ltd. 2010. 30 р.
12. Zimmerer RE, Lawson KD, Calvert CJ. The effects of wearing diapers on skin. Pediatr Dermatol. 1986;3:95–101.
13. Белоусов НА, Горелов АВ. Применение мази Д-пантенол в лечение пеленочного дерматита у новорожденных детей. Вопросы современной педиатрии. 2002;1(4):96.
14. Onder M, Adisen E, Velagic Z. Diaper dermatit. Turkish Pediatr J. 2007;50:129–135.
15. Klunk C, Domingues E, Wiss K. An update on diaper dermatitis. Clin Dermatol. 2014;32(4):477–487.
16. Tuzun Y, Dolar N. Cocuk Bezi Dermatiti. In: Pediyatrik Dermatoloji. Eds. Tuzun Y, Kotogyan A, Serdaroglu S, Cokugras H, Tuzun B, Mat C. Istanbul: Nobel Publishing Ltd. 2005. Р. 113–120.
17. Dixon PN, Warin RP, Mary P. English. Role of candida albicans infection in napkin rashes. Br Med J. 1969;2(5648):23–27.
18. Honig PJ, Gribetz B, Leyden JL, McGinley KJ, Burke LA. Amoxicillin and diaper dermatitis. J Am Acad Dermatol. 1988;19:275–279.
19. Serdaroglu S, Ustunbas TK. Diaper Dermatitis (Napkin Der matitis, Nappy Rash). J Turk Acad Dermatol. 2010;4(4):04401r.
20. Klunk C, Domingues E, Wiss K. An update on diaper dermatitis. Clin Dermatol. 2014;32(4):477–487.
21. Громова ОА. Витамин В5 (Пантотеновая кислота). Школа по витаминам. Практика педиатра. 2005.
22. Putet G, Guy B, Andres P, Sirvent A, de Bony R, Girard F. Effect of Bepanten Ointment in the prevention and treatment of diaper rash on premature and full term babies. Realites Pediatriques. 2001;63:33–38.
23. Тютюнник ВЛ. Трещины сосков у кормящих мам, методы их лечения и профилактики. Русский медицинский журнал. 2004;5:1–3.
24. Ревякина ВА. Современные технологии ухода за кожей у детей с атопическим дерматитом. Лечащий врач. 2004;3:6–7.
25. Яцык ГВ, Акоев ЮС. Клиническая эффективность различных средств по уходу за кожей новорожденных на основе Д-пантенола. Педиатрия. Consilium medicum. 2004;2:14–17.
26. URL: http://www.rlsnet.ru/tn_index_id_446.htm (Available: 11.12.2015).
27. Gehring W, Gloor M. Effect of topically applied dexpanthenol on epidermal barrier function and stratum corneum hydration. Results of a human in vivo study. Arzneimittelforschung. 2000;50:659–663.
28. Иванова НА, Костракина ЛН. Опыт применения бепантена и бепантена плюс в лечении атопического дерматита у детей. Consilium Medicum. 2005;7(1):31–33.
29. Ebner F, Heller A, Rippke F, Tausch I. Am J Clin Dermatol. 2002; 3(6):427–433.
30. Огородова ЛМ, Нагаева А, Ходкевич ЛВ. Эффективность декспантенола в комплексном лечении атопического дерматита у детей. Педиатрическая фармакология. 2003;1(3):54–56
31. Горланов ИА, Леина ЛМ, Милявская ИР. Кожа новорожденных: дифференциальная диагностика патологических состояний, особенности ухода. Медицинский совет. 2013;2:41–50.
32. Делягин ВМ. Пеленочный дерматит. Медицинский совет. 2013;1:12–15.
33. Boiko S. Diapers and diaper rashes. Dermatol Nurs. 1997; 9(1):33–39.
34. Регистр лекарственных средств России. РЛС-2013.21 (Электронная энциклопедия лекарств). М.: РЛС-Патент. 2013.
Review
For citations:
Murashkin N.N., Materikin A.I., Yepishev R.V., Ambarchyan E.T. Peculiarities of the Course and Prevention of Diaper Dermatitis in Newborns and Infants. Current Pediatrics. 2015;14(6):710-713. (In Russ.) https://doi.org/10.15690/vsp.v14i6.1481
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