EXPERIENCE OF THE ADALIMUMAB APPLICATION FOR THE PATIENT WITH EARLY DEBUT OF JUVENILE IDIOPATHIC ARTHRITIS AND UVEITIS
https://doi.org/10.15690/vsp.v13i4.1102
Abstract
The case of early debut and heavy course of juvenile idiopathic arthritis in the patient at the age of 1 year and 8 months, associated with uveitis refractory to the therapy by methotrexate and nonsteroid antiinflammatory preparations is presented. The given clinical example shows high therapeutic efficiency of the adalimumab. To the 8th week of treatment inflammatory changes in conjunctiva were stopped, to the 12th week the stage of inactive illness was registered, i.e. the patient had no inflammatory changes in joints, uveitis activity signs, increase of laboratory indicators of illness activity. Duration of remission of articulate syndrome and uveitis made 9 months.
Supporting agencies: Roche, Pfizer, Bristol-Myers Squibb, Centocor, Novartis.
About the Authors
K. B. Isaeva
Scientific Centre of Children Health, Moscow
Russian Federation
Russian Federation
E. I. Alexeeva
Scientific Centre of Children Health, Moscow;
I.M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
Alexeeva Ekaterina Iosifovna, PhD, professor, Head of the Pediatric Faculty of I. M. Sechenov First MSMU, Head of the Rheumatologic Department of SCCH
R. V. Denisova
Scientific Centre of Children Health, Moscow
Russian Federation
Russian Federation
T. V. Sleptsova
Scientific Centre of Children Health, Moscow
Russian Federation
Russian Federation
Т. М. Bzarova
Scientific Centre of Children Health, Moscow
Russian Federation
Russian Federation
S. I. Valieva
Scientific Centre of Children Health, Moscow
Russian Federation
Russian Federation
E. V. Mitenko
Scientific Centre of Children Health, Moscow
Russian Federation
Russian Federation
E. G. Chistyakova
Scientific Centre of Children Health, Moscow;
I.M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
А. М. Chomakhidze
Scientific Centre of Children Health, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Isaeva K.B., Alexeeva E.I., Denisova R.V., Sleptsova T.V., Bzarova Т.М., Valieva S.I., Mitenko E.V., Chistyakova E.G., Chomakhidze А.М. EXPERIENCE OF THE ADALIMUMAB APPLICATION FOR THE PATIENT WITH EARLY DEBUT OF JUVENILE IDIOPATHIC ARTHRITIS AND UVEITIS. Current Pediatrics. 2014;13(4):156-161. (In Russ.) https://doi.org/10.15690/vsp.v13i4.1102
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