Formula Alternatives for Nutrition Therapy of Children with Cow’s Milk Protein Allergy
https://doi.org/10.15690/vsp.v20i3/2272
Abstract
Well-recognized tactic for the management of formula-fed children with cow’s milk protein allergy (CMPA) is exclusion of whole cow milk protein and its replacement with extensively hydrolyzed or amino acid formula. One of the most topical issue is the choice of therapeutic formula for a child with CMPA. This article presents information about the clinical manifestations of CMPA and describes the principles of nutrition therapy. All the stages of preparation of adapted therapeutic formula are discussed in detail. It has been shown that the choice of therapeutic formula for a child with CMPA depends on the disease clinical manifestations, their severity, and the presence of comorbid conditions. Current requirements for extensively hydrolyzed formula are reduced to limitations in the size of peptides with immunoreactive properties and indicate the need for evidence of the clinical efficacy of such formula in double-blind placebo-controlled studies.
Supporting agencies: The article has been funded by “Nestle”
About the Authors
Gennadiy A. Novik
Saint Petersburg State Pediatric Medical University
Russian Federation
Disclosure of interest:
Russian Federation
Saint Petersburg
Disclosure of interest:
Lecturing for “GlaxoSmithKline”, “Nestle”, “Nutricia”, “Novartis”, “AstraZeneca”, “Abbott”, “Bayer”, “MSD Pharmaceuticals”
Maria V. Zhdanova
Saint Petersburg State Pediatric Medical University
Russian Federation
Disclosure of interest:
Russian Federation
Saint Petersburg
Disclosure of interest:
The other contributors confirmed the absence of a reportable conflict of interests
Yulia O. Zaitseva
Saint Petersburg State Pediatric Medical University
Russian Federation
Disclosure of interest:
Russian Federation
Saint Petersburg
Disclosure of interest:
The other contributors confirmed the absence of a reportable conflict of interests
Anastasiia S. Demidova
Saint Petersburg State Pediatric Medical University
Russian Federation
Disclosure of interest:
Russian Federation
Saint Petersburg
Disclosure of interest:
The other contributors confirmed the absence of a reportable conflict of interests.
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For citations:
Novik G.A., Zhdanova M.V., Zaitseva Yu.O., Demidova A.S. Formula Alternatives for Nutrition Therapy of Children with Cow’s Milk Protein Allergy. Current Pediatrics. 2021;20(3):223-231. (In Russ.) https://doi.org/10.15690/vsp.v20i3/2272
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