ADALIMUMAB IN TREATMENT OF SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS
https://doi.org/10.15690/vsp.v12i6.887
Abstract
A history case of systemic juvenile idiopathic arthritis with early onset and severe clinical case, resistant to treatment with standard immunosuppressive agents is represented in the article. This case demonstrates high clinical efficacy of adalimumab in a patient with severe course of systemic juvenile idiopathic arthritis, prolonged remission of extra-articular involvement and persistent polyarthritis. By the 4th week of the treatment inflammatory changes in the joints had arrested, range of motions had widened, laboratory markers of activity had normalized and non-active stage of the disease had been established. The duration of the remission of articular syndrome was 2 years, no relapses were observed during the follow-up period.
About the Authors
R. V. Denisova
Scientific Centre of Children Health of RAMS, Moscow
Russian Federation
Russian Federation
E. I. Alexeeva
Scientific Centre of Children Health of RAMS, Moscow;
I.M. Sechenov First Moscow State Medical University,
Russian Federation
Russian Federation
K. B. Isaeva
Scientific Centre of Children Health of RAMS, Moscow
Russian Federation
Russian Federation
T. V. Sleptsova
Scientific Centre of Children Health of RAMS, Moscow
Russian Federation
Russian Federation
T. M. Bzarova
Scientific Centre of Children Health of RAMS, Moscow
Russian Federation
Russian Federation
S. I. Valieva
Scientific Centre of Children Health of RAMS, Moscow,
Russian Federation
Russian Federation
E. V. Mitenko
Scientific Centre of Children Health of RAMS, Moscow
Russian Federation
Russian Federation
E. G. Chistyakova
Scientific Centre of Children Health of RAMS, Moscow;
I.M. Sechenov First Moscow State Medical University
Russian Federation
Russian Federation
A. M. Chomakhidze
Scientific Centre of Children Health of RAMS, Moscow
Russian Federation
Russian Federation
A. N. Fetisova
Scientific Centre of Children Health of RAMS, Moscow
Russian Federation
Russian Federation
O. L. Lomakina
Scientific Centre of Children Health of RAMS, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Denisova R.V., Alexeeva E.I., Isaeva K.B., Sleptsova T.V., Bzarova T.M., Valieva S.I., Mitenko E.V., Chistyakova E.G., Chomakhidze A.M., Fetisova A.N., Lomakina O.L. ADALIMUMAB IN TREATMENT OF SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS. Current Pediatrics. 2013;12(6):123-129. (In Russ.) https://doi.org/10.15690/vsp.v12i6.887
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