EXPERIENCE OF OSMOTIC LAXATIVES (POLYETHYLENE GLYCOL 4000) USAGE IN TREATMENT OF CHRONIC CONSTIPATION IN CHILDREN
https://doi.org/10.15690/vsp.v12i4.747
Abstract
Aim: to assess clinical efficacy of polietilenglicol (macrogol) with molecular weight 4000 kDa in children with chronic constipation. Patients and methods: clinical efficacy was assessed in 30 children aged 2–12 years with chronic constipation. The follow-up was performed on an out-patient basis, patients and their parents kept diaries, noting stool characteristics according to the Bristol stool scale. Coprological analysis and abdominal ultrasound were carried out. The duration of the follow-up after the withdrawal of the studied drug was 6 months. Results: during the 1st week of treatment the frequency of stool increased in 23 (76,6%) children, normalization of stool frequency to the 4th week of treatment was achieved in 93,3% of patients. Stool consistency in 1 month of treatment met criteria of the 3d and 4th types according to the Bristol stool scale in 27 (90%) children. Painful defecations have been arrested by the 3d week of treatment. Conclusions: the drug was shown to be highly effective in treatment of chronic constipation in children, arresting such symptoms as «fear of the potty» and painful defecations and having a strong positive dynamics after its withdrawal.
About the Author
A. V. Eremeeva
I.M. Sechenov First Moscow State Medical University,
Russian Federation
Eremeeva Alina Vladimirovna, MD, assistant professor of the Department of Pediatrics of Pediatric Faculty
Russian Federation
Eremeeva Alina Vladimirovna, MD, assistant professor of the Department of Pediatrics of Pediatric Faculty
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Review
For citations:
Eremeeva A.V. EXPERIENCE OF OSMOTIC LAXATIVES (POLYETHYLENE GLYCOL 4000) USAGE IN TREATMENT OF CHRONIC CONSTIPATION IN CHILDREN. Current Pediatrics. 2013;12(4):172-175. (In Russ.) https://doi.org/10.15690/vsp.v12i4.747
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