Роль системного воспаления в развитии психических расстройств у детей: обзор литературы

По всему миру отмечается значительный рост распространенности психических расстройств среди детского населения. Особую обеспокоенность вызывает рост числа случаев аутизма, интеллектуальной недостаточности, гиперкинетических расстройств и шизофрении. Уточнение этиологии и патогенеза психических расстройств — ключевая задача исследователей. Роль системного воспаления в развитии психических нарушений на сегодняшний день остается наименее изученной. Однако уже сейчас можно утверждать, что важным фактором, ассоциированным с развитием психических расстройств как у взрослых, так и у детей является генерализация периферического воспаления. В обзоре представлены актуальные данные, а также авторская оценка роли системного воспаления в развитии наиболее распространенных психических расстройств у детей. Проведен сравнительный анализ признаков острого и хронического системного воспаления. Выделены основные патогенетические механизмы «системного повреждения» при психических расстройствах.

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